SE8500339L - PERSONAL HISTAMIN, ITS PREPARATION AND USE - Google Patents

PERSONAL HISTAMIN, ITS PREPARATION AND USE

Info

Publication number
SE8500339L
SE8500339L SE8500339A SE8500339A SE8500339L SE 8500339 L SE8500339 L SE 8500339L SE 8500339 A SE8500339 A SE 8500339A SE 8500339 A SE8500339 A SE 8500339A SE 8500339 L SE8500339 L SE 8500339L
Authority
SE
Sweden
Prior art keywords
histamine
carrier
hydrogen
derivative
bound
Prior art date
Application number
SE8500339A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8500339D0 (en
Inventor
E Akerblom
A Norrman
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE8500339A priority Critical patent/SE8500339L/en
Publication of SE8500339D0 publication Critical patent/SE8500339D0/en
Priority to AU53963/86A priority patent/AU5396386A/en
Priority to ES551220A priority patent/ES8702369A1/en
Priority to JP61500909A priority patent/JPS62501560A/en
Priority to PCT/SE1986/000027 priority patent/WO1986004331A1/en
Priority to EP86901155A priority patent/EP0208776A1/en
Publication of SE8500339L publication Critical patent/SE8500339L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Carrier-bound histamine comprising histamine in the form of an aliphatically bound 4-(2-aminoethyl)-imidazolyl group. Process for binding histamine covalently to a carrier containing at least one functional group Y, in that a histamine derivative of formula (I) in which R1NH is a group which is chemically inert to X and Y, with R1 being hydrogen or a protective group capable of being split off; n is an integer of less than 10; m is an integer of 0 or 1; B is an inert organic bridge; and X and Y are functional groups such that X and Y can be reacted chemically with each other to form a covalent structure binding together said histamine derivative and said carrier; is contacted with said carrier so that X and Y are reacted with each other to covalently bind said derivative and carrier together, whereupon, if R1 is other than hydrogen, R1 is converted chemically to hydrogen. The carrier-bound histamine can be used for chromatography and in immunological assay methods.
SE8500339A 1985-01-24 1985-01-24 PERSONAL HISTAMIN, ITS PREPARATION AND USE SE8500339L (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE8500339A SE8500339L (en) 1985-01-24 1985-01-24 PERSONAL HISTAMIN, ITS PREPARATION AND USE
AU53963/86A AU5396386A (en) 1985-01-24 1986-01-24 Carrier-bound histamine, its manufacture and its use
ES551220A ES8702369A1 (en) 1985-01-24 1986-01-24 Carrier-bound histamine, its manufacture and its use.
JP61500909A JPS62501560A (en) 1985-01-24 1986-01-24 Carrier-bound histamine, its preparation and use
PCT/SE1986/000027 WO1986004331A1 (en) 1985-01-24 1986-01-24 Carrier-bound histamine, its manufacture and its use
EP86901155A EP0208776A1 (en) 1985-01-24 1986-01-24 Carrier-bound histamine, its manufacture and its use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8500339A SE8500339L (en) 1985-01-24 1985-01-24 PERSONAL HISTAMIN, ITS PREPARATION AND USE

Publications (2)

Publication Number Publication Date
SE8500339D0 SE8500339D0 (en) 1985-01-24
SE8500339L true SE8500339L (en) 1986-07-25

Family

ID=20358885

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8500339A SE8500339L (en) 1985-01-24 1985-01-24 PERSONAL HISTAMIN, ITS PREPARATION AND USE

Country Status (6)

Country Link
EP (1) EP0208776A1 (en)
JP (1) JPS62501560A (en)
AU (1) AU5396386A (en)
ES (1) ES8702369A1 (en)
SE (1) SE8500339L (en)
WO (1) WO1986004331A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1302919C (en) * 1985-07-03 1992-06-09 Robert T. Buckler Histamine derivatives, immunogen conjugates and antibodies raised thereto
DE4025726A1 (en) * 1990-08-14 1992-02-20 Boehringer Mannheim Gmbh DETERMINATION OF BIOGENIC AMINES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2301532A (en) * 1938-08-18 1942-11-10 Parke Davis & Co Biological product and process of obtaining same
US2372066A (en) * 1940-12-23 1945-03-20 Parke Davis & Co Biological product and process of obtaining same
GB1341375A (en) * 1969-11-19 1973-12-19 Smith Kline French Lab Aminoalkylimidazoles and process for their production
GB1316990A (en) * 1970-09-17 1973-05-16 Roche Products Ltd Imidazolyl derivatives
US3873697A (en) * 1972-11-11 1975-03-25 Mack Chem Pharm Histamine antigen
US4016146A (en) * 1974-12-10 1977-04-05 Biological Developments, Inc. Phenethylamine antigenic conjugates, their preparation, antibodies, and use
DE3322117A1 (en) * 1983-06-20 1984-12-20 Diamalt AG, 8000 München METHOD FOR PRODUCING N (ARROW UP) (TAU) (ARROW UP) SUBSTITUTED HISTIDE INDIATIVATIVES, N (ARROW UP) (TAU) (ARROW UP) SUBSTITUTED HISTIDE INDIATIVES AND THEIR USE

Also Published As

Publication number Publication date
AU5396386A (en) 1986-08-13
WO1986004331A1 (en) 1986-07-31
ES8702369A1 (en) 1986-12-16
EP0208776A1 (en) 1987-01-21
SE8500339D0 (en) 1985-01-24
JPS62501560A (en) 1987-06-25
ES551220A0 (en) 1986-12-16

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Effective date: 19880328