SE8403376L - SPIROSUCCINIMIDES, THEIR PREPARATION AND USE - Google Patents

SPIROSUCCINIMIDES, THEIR PREPARATION AND USE

Info

Publication number
SE8403376L
SE8403376L SE8403376A SE8403376A SE8403376L SE 8403376 L SE8403376 L SE 8403376L SE 8403376 A SE8403376 A SE 8403376A SE 8403376 A SE8403376 A SE 8403376A SE 8403376 L SE8403376 L SE 8403376L
Authority
SE
Sweden
Prior art keywords
spirosuccinimides
preparation
compounds
formula
production
Prior art date
Application number
SE8403376A
Other languages
Swedish (sv)
Other versions
SE8403376D0 (en
Inventor
G Bolliger
E Schenker
R Spiegel
H Weidmann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8403376D0 publication Critical patent/SE8403376D0/en
Publication of SE8403376L publication Critical patent/SE8403376L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Compounds having the formula (I) wherein A, R2, R3, R4, R5, X1, X2, m and n have the meaning given in claim 1, production thereof and drugs containing said compounds.
SE8403376A 1983-06-27 1984-06-25 SPIROSUCCINIMIDES, THEIR PREPARATION AND USE SE8403376L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH350383 1983-06-27
CH350583 1983-06-27
CH350483 1983-06-27

Publications (2)

Publication Number Publication Date
SE8403376D0 SE8403376D0 (en) 1984-06-25
SE8403376L true SE8403376L (en) 1984-12-28

Family

ID=27174377

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8403376A SE8403376L (en) 1983-06-27 1984-06-25 SPIROSUCCINIMIDES, THEIR PREPARATION AND USE

Country Status (16)

Country Link
AU (1) AU2983384A (en)
DE (1) DE3422411A1 (en)
DK (1) DK310184A (en)
ES (1) ES8601202A1 (en)
FI (1) FI842547A (en)
FR (1) FR2549061A1 (en)
GB (1) GB2142332A (en)
GR (1) GR82274B (en)
HU (1) HUT36793A (en)
IL (1) IL72218A0 (en)
IT (1) IT1199148B (en)
LU (1) LU85434A1 (en)
NL (1) NL8401907A (en)
PT (1) PT78787B (en)
SE (1) SE8403376L (en)
WO (1) WO1985000171A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431195A1 (en) * 1984-08-24 1986-03-06 Troponwerke GmbH & Co KG, 5000 Köln NEW BENZODIAZEPINES, PROCESS FOR THEIR PRODUCTION AND THEIR USE
EP0273659A1 (en) * 1986-12-27 1988-07-06 Takeda Chemical Industries, Ltd. Azaspiro compounds, their production and use
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
JP2800953B2 (en) * 1990-07-06 1998-09-21 住友製薬株式会社 New imide derivatives
BE1007765A5 (en) 1994-06-27 1995-10-17 Blagden Ind Plc Total metal was open.
AU2206699A (en) * 1997-12-23 1999-07-12 Alcon Laboratories, Inc. Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions
AU2003245753B2 (en) 2002-07-05 2009-12-24 Targacept, Inc. N-aryl diazaspiracyclic compounds and methods of preparation and use thereof
WO2005023809A1 (en) * 2003-09-10 2005-03-17 Virochem Pharma Inc. Spiro compounds and methods for the modulation of chemokine receptor activity
US9017724B2 (en) 2004-02-24 2015-04-28 The General Hospital Corporation Catalytic radiofluorination
US8257680B1 (en) 2004-02-24 2012-09-04 The General Hospital Corporation Catalytic radiofluorination
JO2676B1 (en) 2004-04-06 2012-06-17 جانسين فارماسوتيكا ان. في Substituted diaza-spiro-(4,5)-Decane derivatives and their use as neurokinin antagonists
EP1858896B1 (en) 2005-03-08 2010-08-18 Janssen Pharmaceutica NV Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists
US8450466B2 (en) * 2008-03-21 2013-05-28 The General Hosptial Corporation Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB936477A (en) * 1959-03-25 1963-09-11 Sandoz Ltd Improvements in or relating to substituted succinimides
DE1211646B (en) * 1959-03-25 1966-03-03 Sandoz Ag Process for the preparation of spirosuccinimides and their salts
US3198800A (en) * 1964-05-07 1965-08-03 Sandoz Ltd 2, 8-(para-f-4-oxo-butyl)-diazaspiro[4, 5]-decane-1, 3-diones
BE897058A (en) * 1982-06-25 1983-12-16 Sandoz Sa USE OF A SPIRO-SUCCINIMIDE DERIVATIVE IN THE TREATMENT OF ALZHEIMER-TYPE DEMENTIA

Also Published As

Publication number Publication date
GB8416172D0 (en) 1984-08-01
DK310184D0 (en) 1984-06-25
DK310184A (en) 1984-12-28
NL8401907A (en) 1985-01-16
PT78787B (en) 1986-06-05
FI842547A (en) 1984-12-28
IL72218A0 (en) 1984-10-31
SE8403376D0 (en) 1984-06-25
FR2549061A1 (en) 1985-01-18
PT78787A (en) 1984-07-01
AU2983384A (en) 1985-01-03
ES533735A0 (en) 1985-10-16
IT8448458A0 (en) 1984-06-26
GB2142332A (en) 1985-01-16
ES8601202A1 (en) 1985-10-16
FI842547A0 (en) 1984-06-25
DE3422411A1 (en) 1985-01-03
LU85434A1 (en) 1985-03-26
HUT36793A (en) 1985-10-28
WO1985000171A1 (en) 1985-01-17
IT1199148B (en) 1988-12-30
GR82274B (en) 1984-12-13

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