SE8402649L - PREPARATION OF 1,8-DIHYDROXY-10-ACYL-9 ANTHONES - Google Patents

PREPARATION OF 1,8-DIHYDROXY-10-ACYL-9 ANTHONES

Info

Publication number
SE8402649L
SE8402649L SE8402649A SE8402649A SE8402649L SE 8402649 L SE8402649 L SE 8402649L SE 8402649 A SE8402649 A SE 8402649A SE 8402649 A SE8402649 A SE 8402649A SE 8402649 L SE8402649 L SE 8402649L
Authority
SE
Sweden
Prior art keywords
dihydroxy
acyl
preparation
anthones
replaced
Prior art date
Application number
SE8402649A
Other languages
Swedish (sv)
Other versions
SE8402649D0 (en
SE453827B (en
Inventor
P J Kairisalo
A K Pippuri
E J Honkanen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of SE8402649D0 publication Critical patent/SE8402649D0/en
Publication of SE8402649L publication Critical patent/SE8402649L/en
Publication of SE453827B publication Critical patent/SE453827B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C07C49/737—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having three rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to a method for the preparation of 1,8-dihydroxy-10-acyl-9-anthrones, especially for use in the treatment of psoriasis, having the formula: <IMAGE> where R is an alkyl group having 2-4 carbon atoms, by using as the initial material, 1,8-dihydroxy-9-anthrone and an acid chloride having the formula RCOC2, where R represents the same as above. In accordance with the invention, harmful benzene is replaced with, for example toluene; this replacing is possible because pyridine is replaced with 2,6-dimethyl pyridine.
SE8402649A 1983-05-18 1984-05-16 PROCEDURE FOR THE PREPARATION OF 1,8-DIHYDROXY-10-ACYL-9 ANTRONES SE453827B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI831739A FI66585C (en) 1983-05-18 1983-05-18 FOERFARANDE FOER FRAMSTAELLNING AV SAERSKILT VID BEHANDLING AVSORIASIS ANVAENDBARA 1,8-DIHYDROXI-10-ACYL-9-ANTRONER

Publications (3)

Publication Number Publication Date
SE8402649D0 SE8402649D0 (en) 1984-05-16
SE8402649L true SE8402649L (en) 1984-11-19
SE453827B SE453827B (en) 1988-03-07

Family

ID=8517222

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8402649A SE453827B (en) 1983-05-18 1984-05-16 PROCEDURE FOR THE PREPARATION OF 1,8-DIHYDROXY-10-ACYL-9 ANTRONES

Country Status (31)

Country Link
JP (1) JPS59212443A (en)
KR (1) KR840009059A (en)
AU (1) AU560079B2 (en)
BE (1) BE899334A (en)
CA (1) CA1212943A (en)
CH (1) CH659464A5 (en)
CS (1) CS256379B2 (en)
DD (1) DD223702A5 (en)
DE (1) DE3418382A1 (en)
DK (1) DK154207C (en)
ES (1) ES531760A0 (en)
FI (1) FI66585C (en)
FR (1) FR2546162B1 (en)
GB (1) GB2140007B (en)
GR (1) GR79971B (en)
HU (1) HUT36076A (en)
IL (1) IL71446A (en)
IN (1) IN156115B (en)
IS (1) IS2902A7 (en)
IT (1) IT1173473B (en)
LU (1) LU85292A1 (en)
NL (1) NL8401074A (en)
NO (1) NO157099C (en)
NZ (1) NZ207592A (en)
PH (1) PH20038A (en)
PL (1) PL141866B1 (en)
PT (1) PT78603B (en)
SE (1) SE453827B (en)
SU (1) SU1240351A3 (en)
YU (1) YU81784A (en)
ZA (1) ZA842223B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492372A1 (en) * 1980-10-21 1982-04-23 Cird 1,8-DIHYDROXY-9-ANTHRONES SUBSTITUTED IN POSITION 10 AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS
US4843097A (en) * 1984-06-13 1989-06-27 Groupement D'interet Economique Dit: Centre International De Recherches Dermatologiques C.I.R.D. 10-aryl-1,8-dihydroxy-9-anthrones and their esters, process for preparing same, and use of same in human and veterinary medicine and in cosmetics
FR2591222B1 (en) * 1985-12-11 1988-07-22 Cird MONO, DI AND TRI-ESTERS OF 1,8-DIHYDROXY PHENYL-10 ANTHRONE-9 OR ANTHRANOL-9, THEIR PREPARATION PROCESS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS
FR2566772B1 (en) * 1984-06-29 1986-11-14 Cird DIACYLOXY-1,8 ACYL-10 ANTHRONES, THEIR PREPARATION PROCESS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS
FR2580631B1 (en) * 1985-04-17 1987-05-29 Cird HYDROXY-1 ACYLOXY-8 ACYL-10 ANTHRONES, THEIR PREPARATION PROCESS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS
EP0535952B1 (en) * 1991-10-04 1997-12-29 FISHER &amp; PAYKEL LIMITED Humidifier
DE4231636A1 (en) * 1992-09-22 1994-03-24 Beiersdorf Ag New anthrone and anthracene derivatives substituted in the 10-position, processes for their preparation, pharmaceutical or cosmetic compositions containing these compounds and their use
US5426197A (en) * 1993-07-19 1995-06-20 Teva Pharmaceutical Industries, Ltd. 10-substituted 1,8-dihydroxy-9(10H) anthracenone pharmaceuticals

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI57743C (en) * 1979-03-29 1980-10-10 Orion Yhtymae Oy FREQUENCY REQUIREMENT FOR NYA 1,8-DIHYDROXI-10-ACYL-9-ANTRONER MOT PSORIASIS

Also Published As

Publication number Publication date
IN156115B (en) 1985-05-18
SE8402649D0 (en) 1984-05-16
IL71446A0 (en) 1984-07-31
GR79971B (en) 1984-10-31
PT78603B (en) 1986-06-26
CA1212943A (en) 1986-10-21
SE453827B (en) 1988-03-07
NO841965L (en) 1984-11-19
FI831739A0 (en) 1983-05-18
BE899334A (en) 1984-07-31
YU81784A (en) 1986-10-31
NL8401074A (en) 1984-12-17
GB8408666D0 (en) 1984-05-16
AU560079B2 (en) 1987-03-26
IT8420213A0 (en) 1984-03-23
JPS59212443A (en) 1984-12-01
LU85292A1 (en) 1984-10-26
KR840009059A (en) 1984-12-24
NO157099C (en) 1988-01-20
DK154207B (en) 1988-10-24
FR2546162A1 (en) 1984-11-23
FI66585C (en) 1984-11-12
DK173584D0 (en) 1984-03-30
ES8505167A1 (en) 1985-05-16
HUT36076A (en) 1985-08-28
IL71446A (en) 1987-01-30
SU1240351A3 (en) 1986-06-23
DK154207C (en) 1989-03-13
DE3418382A1 (en) 1984-11-22
PT78603A (en) 1984-06-01
CS291184A2 (en) 1987-08-13
PH20038A (en) 1986-09-04
FI66585B (en) 1984-07-31
ES531760A0 (en) 1985-05-16
NO157099B (en) 1987-10-12
CS256379B2 (en) 1988-04-15
FR2546162B1 (en) 1987-01-30
NZ207592A (en) 1986-11-12
DK173584A (en) 1984-11-19
GB2140007A (en) 1984-11-21
PL141866B1 (en) 1987-09-30
GB2140007B (en) 1986-04-09
PL247724A1 (en) 1985-06-18
ZA842223B (en) 1984-11-28
DD223702A5 (en) 1985-06-19
IT1173473B (en) 1987-06-24
IS2902A7 (en) 1984-06-07
CH659464A5 (en) 1987-01-30
AU2599884A (en) 1984-11-22

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