SE8402561L - PHARMACEUTICAL COMPOSITION - Google Patents

PHARMACEUTICAL COMPOSITION

Info

Publication number
SE8402561L
SE8402561L SE8402561A SE8402561A SE8402561L SE 8402561 L SE8402561 L SE 8402561L SE 8402561 A SE8402561 A SE 8402561A SE 8402561 A SE8402561 A SE 8402561A SE 8402561 L SE8402561 L SE 8402561L
Authority
SE
Sweden
Prior art keywords
alkyl
pharmaceutical composition
ester
pyrrolidone
aliphatic
Prior art date
Application number
SE8402561A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8402561D0 (en
Inventor
J Heller
W A Skinner
K Saito
S Satoh
Y Takakura
Y Itoh
Original Assignee
Nitto Electric Ind Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Electric Ind Co filed Critical Nitto Electric Ind Co
Publication of SE8402561D0 publication Critical patent/SE8402561D0/en
Publication of SE8402561L publication Critical patent/SE8402561L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pharmaceutical composition for administration to the skin comprises a pharmaceutical agent, e.g. benzodiazepine, and a percutaneous carrier liquid comprising: A) a 5-24C aliphatic or cycloaliphatic hydrocarbon which may be halo-substituted, an ester of an alcohol and a 7-18C aliphatic carboxylic acid, a C10-18 mono- or di-ether, and/or a C11-15 ketone; and B) a thiogylercol, lactic acid or ester, cyclic urea, alkyl or acyl urea, alkyl amide and/or pyrrolidone or N-alkyl pyrrolidone.
SE8402561A 1983-05-20 1984-05-11 PHARMACEUTICAL COMPOSITION SE8402561L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49673283A 1983-05-20 1983-05-20

Publications (2)

Publication Number Publication Date
SE8402561D0 SE8402561D0 (en) 1984-05-11
SE8402561L true SE8402561L (en) 1984-11-21

Family

ID=23973888

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8402561A SE8402561L (en) 1983-05-20 1984-05-11 PHARMACEUTICAL COMPOSITION

Country Status (8)

Country Link
CA (1) CA1225594A (en)
CH (1) CH657531A5 (en)
DE (1) DE3418565C2 (en)
DK (1) DK239984A (en)
FR (1) FR2547503B1 (en)
GB (1) GB2141025B (en)
NL (1) NL8401422A (en)
SE (1) SE8402561L (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4637930A (en) * 1984-02-08 1987-01-20 Yamanouchi Pharmaceutical Co, Ltd. Transdermal formulation of nicardipine hydrochloride
JPS61280426A (en) * 1985-06-04 1986-12-11 Ikeda Mohandou:Kk Anti-inflammatory and analgesic application agent
US4826686A (en) * 1985-12-14 1989-05-02 Boehringer Ingelheim Kg Therapeutic system
CH666621A5 (en) * 1986-06-27 1988-08-15 Ciba Geigy Ag TOPICALLY APPLICABLE PHARMACEUTICAL COMPOSITIONS WITH SYSTEMIC EFFECT.
US4861764A (en) * 1986-11-17 1989-08-29 Macro Chem. Corp. Percutaneous absorption enhancers, compositions containing same and method of use
GB8718886D0 (en) * 1987-08-10 1987-09-16 Ici America Inc Composition
CA1334646C (en) * 1988-04-08 1995-03-07 James Vanolden Peck Transdermal penetration enhancers
US5246949A (en) * 1989-12-06 1993-09-21 Sansho Co., Ltd. Preparation for endermism containing dopamine derivatives
JPH03236317A (en) * 1989-12-06 1991-10-22 Sansei Seiyaku Kk Dopamine derivative-containing percutaneous
WO1994021262A1 (en) * 1993-03-17 1994-09-29 Alza Corporation Device for the transdermal administration of alprazolam
DE4432429A1 (en) * 1994-09-12 1996-03-14 Heinz Prahm Pharmaceutical concentrates contg. lactic acid
US5693335A (en) * 1995-06-07 1997-12-02 Cygnus, Inc. Skin permeation enhancer composition for use with sex steroids
DE19949202A1 (en) * 1999-10-13 2001-05-03 Lohmann Therapie Syst Lts Transdermal therapeutic system for the delivery of acetylsalicylic acid and / or salicylic acid
KR20080080087A (en) * 2005-09-30 2008-09-02 티티아이 엘뷰 가부시키가이샤 Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles
US7848801B2 (en) 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1158283A (en) * 1965-10-21 1969-07-16 Foster Milburn Company Composition to be Applied to Skin and Process for Preparing Same.
FR2001768A1 (en) * 1968-02-12 1969-10-03 Gillette Co N-Alkyl-2-pyrrolidone to improve cutaneous absorption - methyl, ethyl and n-butyl pyrrolidone(s), opt. with water and/or ethanol give improved skin penetration
SE325667B (en) * 1968-03-06 1970-07-06 Medisan Ab
US3472931A (en) * 1969-01-17 1969-10-14 Foster Milburn Co Percutaneous absorption with lower alkyl amides
GB1404583A (en) * 1971-10-08 1975-09-03 Vymatt Sa Urea compositions and methods of preparation thereof
GB1504302A (en) * 1974-08-23 1978-03-15 Fisons Ltd Sedative method and composition
US3957994A (en) * 1974-12-19 1976-05-18 Nelson Research & Development Company Topical anti-inflammatory composition and method of use
US3932653A (en) * 1974-12-19 1976-01-13 Nelson Research & Development Co. Composition and method for topical administration of griseofulvin
US4017641A (en) * 1975-01-31 1977-04-12 The Procter & Gamble Company Skin moisturizing compositions containing 2-pyrrolidinone
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4038417A (en) * 1975-06-19 1977-07-26 Nelson Research & Development Company Method for treatment of psoriasis
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
CA1165240A (en) * 1980-07-09 1984-04-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
FR2502951B1 (en) * 1981-04-06 1985-12-06 Sandoz Sa TOPICAL PHARMACEUTICAL COMPOSITIONS IN THE FORM OF A MICRO-EMULSION

Also Published As

Publication number Publication date
SE8402561D0 (en) 1984-05-11
DE3418565A1 (en) 1984-11-22
CA1225594A (en) 1987-08-18
GB2141025A (en) 1984-12-12
DK239984D0 (en) 1984-05-15
DE3418565C2 (en) 1992-05-27
GB2141025B (en) 1986-09-17
GB8412569D0 (en) 1984-06-20
NL8401422A (en) 1984-12-17
DK239984A (en) 1984-11-21
FR2547503B1 (en) 1987-11-20
CH657531A5 (en) 1986-09-15
FR2547503A1 (en) 1984-12-21

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Ref document number: 8402561-8

Effective date: 19880917