SE8302758L - Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening - Google Patents

Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening

Info

Publication number
SE8302758L
SE8302758L SE8302758A SE8302758A SE8302758L SE 8302758 L SE8302758 L SE 8302758L SE 8302758 A SE8302758 A SE 8302758A SE 8302758 A SE8302758 A SE 8302758A SE 8302758 L SE8302758 L SE 8302758L
Authority
SE
Sweden
Prior art keywords
compound
splitting
organic
bond
carbon atom
Prior art date
Application number
SE8302758A
Other languages
English (en)
Swedish (sv)
Other versions
SE8302758D0 (sv
Inventor
R E A V Axen
J P E Carlsson
H N Y Drevin
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE8302758A priority Critical patent/SE8302758L/xx
Publication of SE8302758D0 publication Critical patent/SE8302758D0/xx
Priority to US06/700,819 priority patent/US4647655A/en
Priority to AT84850153T priority patent/ATE30314T1/de
Priority to EP84850153A priority patent/EP0128885B1/de
Priority to DE8484850153T priority patent/DE3466874D1/de
Priority to JP59502191A priority patent/JPS60501310A/ja
Priority to PCT/SE1984/000186 priority patent/WO1984004525A1/en
Publication of SE8302758L publication Critical patent/SE8302758L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/122—Hydrolysis with acids different from HF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B45/00—Formation or introduction of functional groups containing sulfur
    • C07B45/06—Formation or introduction of functional groups containing sulfur of mercapto or sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/809—Drug, bio-affecting and body treating compositions involving immunoglobulin or antibody fragment, e.g. fab', fv, fc, heavy chain or light chain
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/862—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgE or IgD
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
SE8302758A 1983-05-17 1983-05-17 Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening SE8302758L (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE8302758A SE8302758L (sv) 1983-05-17 1983-05-17 Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening
US06/700,819 US4647655A (en) 1983-05-17 1984-05-16 Method for splitting di-sulphide bonds and a compound obtained thereby
AT84850153T ATE30314T1 (de) 1983-05-17 1984-05-16 Verfahren zum spalten von disulfid-bindungen.
EP84850153A EP0128885B1 (de) 1983-05-17 1984-05-16 Verfahren zum Spalten von Disulfid-Bindungen
DE8484850153T DE3466874D1 (en) 1983-05-17 1984-05-16 A method for splitting di-sulphide bonds
JP59502191A JPS60501310A (ja) 1983-05-17 1984-05-16 ジスルフイツド結合の解裂法
PCT/SE1984/000186 WO1984004525A1 (en) 1983-05-17 1984-05-16 A method for splitting di-sulphide bonds and a compound obtained thereby

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8302758A SE8302758L (sv) 1983-05-17 1983-05-17 Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening

Publications (2)

Publication Number Publication Date
SE8302758D0 SE8302758D0 (sv) 1983-05-17
SE8302758L true SE8302758L (sv) 1984-11-18

Family

ID=20351202

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8302758A SE8302758L (sv) 1983-05-17 1983-05-17 Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening

Country Status (7)

Country Link
US (1) US4647655A (de)
EP (1) EP0128885B1 (de)
JP (1) JPS60501310A (de)
AT (1) ATE30314T1 (de)
DE (1) DE3466874D1 (de)
SE (1) SE8302758L (de)
WO (1) WO1984004525A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879249A (en) * 1983-02-25 1989-11-07 Baldwin Thomas O Linker compounds, linker-compound-ligands and linker-compound-receptors
DE3440988A1 (de) * 1984-11-09 1986-07-10 Hoechst Ag, 6230 Frankfurt Verfahren zur spaltung von peptiden und proteinen an der methionyl-bindung
US4698420A (en) * 1985-02-25 1987-10-06 Xoma Corporation Antibody hybrid molecules and process for their preparation
US5283323A (en) * 1985-08-07 1994-02-01 The United States Of America As Represented By The Department Of Health And Human Services Method of producing immune response
US4877868A (en) * 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
US5395924A (en) * 1986-03-20 1995-03-07 Dana-Farber Cancer Institute, Inc. Blocked lectins; methods and affinity support for making the same using affinity ligands; and method of killing selected cell populations having reduced non-selective cytotoxicity
US5239062A (en) * 1986-03-20 1993-08-24 Dana-Farber Cancer Institute, Inc. Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity
US4794082A (en) * 1987-02-17 1988-12-27 Hoechst Celanese Corporation Biotinylating agents
DE3809986A1 (de) * 1988-03-24 1989-10-05 Boehringer Mannheim Gmbh Verbindungen zur einfuehrung einer sh-gruppe in tyrosin
US5612016A (en) * 1988-04-01 1997-03-18 Immunomedics, Inc. Conjugates of antibodies and bifunctional ligands
US5137877B1 (en) * 1990-05-14 1996-01-30 Bristol Myers Squibb Co Bifunctional linking compounds conjugates and methods for their production
US5378813A (en) * 1992-05-29 1995-01-03 President And Fellows Of Harvard College Meso-2,5-dimercapto-N,N,N'N'-tetramethyladipamide
FR2710340B1 (fr) * 1993-09-22 1995-12-15 D Hinterland Lucien Dussourd Dérivés peptidiques de l'alpha-MSH et leur application .
SE9700769D0 (sv) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
WO2003002908A1 (en) * 2000-06-26 2003-01-09 Reveo, Inc. Backlight for a liquid crystal display having high light-recycling efficiency
US7094351B2 (en) * 2000-10-12 2006-08-22 Corcoran Robert C Purification of substances by reaction affinity chromatography

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE430062B (sv) * 1977-03-04 1983-10-17 Pharmacia Fine Chemicals Ab Kopplings- eller tioleringsreagens
SE427505B (sv) * 1977-03-04 1983-04-11 Pharmacia Diagnostics Ab Reagens till anvendning vid immunkemiska bestemningsmetoder
SE431758B (sv) * 1977-03-04 1984-02-27 Pharmacia Fine Chemicals Ab Som tioleringsreagens eller berarmatris for enzymer anvendbart derivat av en sh-grupphaltig polymer
DE2917001A1 (de) * 1978-04-28 1979-11-08 Toyo Jozo Kk Neue disulfidverbindungen
US4258193A (en) * 1978-07-13 1981-03-24 Toyo Jozo Kabushiki Kaisha Disulfide derivatives having S--S exchange reactivity
SE8102193L (sv) * 1981-04-06 1982-10-07 Pharmacia Ab Terapeutiskt aktiv organisk forening och dess anvendning
SE8102194L (sv) * 1981-04-06 1982-10-07 Pharmacia Ab Terapeutiskt aktiv organisk forening och farmaceutisk beredning innehallande denna
US4511501A (en) * 1982-09-13 1985-04-16 Board Of Regents, The University Of Texas System Bis-amide disulfide cleavable cross-linking reagents

Also Published As

Publication number Publication date
JPH0561279B2 (de) 1993-09-06
DE3466874D1 (en) 1987-11-26
WO1984004525A1 (en) 1984-11-22
JPS60501310A (ja) 1985-08-15
ATE30314T1 (de) 1987-11-15
EP0128885A1 (de) 1984-12-19
SE8302758D0 (sv) 1983-05-17
US4647655A (en) 1987-03-03
EP0128885B1 (de) 1987-10-21

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