SE8302126L - PROCEDURE FOR MANUFACTURING ANTRA-CYCLINE ANTIBIOTICS WITH ANTICANCER EFFECT, AND NEW MICRO-ORGANISM - Google Patents

PROCEDURE FOR MANUFACTURING ANTRA-CYCLINE ANTIBIOTICS WITH ANTICANCER EFFECT, AND NEW MICRO-ORGANISM

Info

Publication number
SE8302126L
SE8302126L SE8302126A SE8302126A SE8302126L SE 8302126 L SE8302126 L SE 8302126L SE 8302126 A SE8302126 A SE 8302126A SE 8302126 A SE8302126 A SE 8302126A SE 8302126 L SE8302126 L SE 8302126L
Authority
SE
Sweden
Prior art keywords
antra
organism
procedure
manufacturing
anticancer effect
Prior art date
Application number
SE8302126A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE455705B (en
SE8302126D0 (en
Inventor
L P Ivanitskaya
L V Egorov
S E Esipov
S I Veselova
V S Soifer
E M Singal
M M Taig
L N Ostanina
S M Navashin
E I Krjuchkova
A I Chernyshev
T G Terentieva
I P Fomina
N A Kljuev
Original Assignee
Vnii Antibiotikov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vnii Antibiotikov filed Critical Vnii Antibiotikov
Publication of SE8302126D0 publication Critical patent/SE8302126D0/en
Publication of SE8302126L publication Critical patent/SE8302126L/en
Publication of SE455705B publication Critical patent/SE455705B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 30 DEG C and at a pH of 6 - 8.5 for 48 - 96 h.
SE8302126A 1982-06-29 1983-04-15 PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC SUBSTANCES AKLACINOMYCIN A AND B BY CULTIVATION OF STREPTOMYCES LAVENDOFOLIAE CBS 26183 AND STREPTOMYCES LAVENDOFOLIAE CBS 26183 SE455705B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU823459347A SU1069433A1 (en) 1982-06-29 1982-06-29 Strain streptonuces lavendofolial 12/3a producer of alkacynomycins a and b

Publications (3)

Publication Number Publication Date
SE8302126D0 SE8302126D0 (en) 1983-04-15
SE8302126L true SE8302126L (en) 1983-12-30
SE455705B SE455705B (en) 1988-08-01

Family

ID=21018792

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8302126A SE455705B (en) 1982-06-29 1983-04-15 PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC SUBSTANCES AKLACINOMYCIN A AND B BY CULTIVATION OF STREPTOMYCES LAVENDOFOLIAE CBS 26183 AND STREPTOMYCES LAVENDOFOLIAE CBS 26183

Country Status (8)

Country Link
AT (1) AT379828B (en)
CH (1) CH657375A5 (en)
DK (1) DK293483A (en)
FI (1) FI72534C (en)
IT (1) IT1194291B (en)
NO (1) NO157825C (en)
SE (1) SE455705B (en)
SU (1) SU1069433A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970000591B1 (en) * 1993-09-03 1997-01-14 동국제약 주식회사 New strain of streptomyces lavendofoliae dkrs and preparation of aclacinomycin a,b and y and glycon using the same

Also Published As

Publication number Publication date
IT1194291B (en) 1988-09-14
IT8321847A1 (en) 1984-12-29
NO831808L (en) 1983-12-30
SE455705B (en) 1988-08-01
FI831383A0 (en) 1983-04-22
DK293483A (en) 1983-12-30
FI72534B (en) 1987-02-27
FI831383L (en) 1983-12-30
SU1069433A1 (en) 1984-11-23
DK293483D0 (en) 1983-06-24
CH657375A5 (en) 1986-08-29
ATA199983A (en) 1985-07-15
NO157825B (en) 1988-02-15
IT8321847A0 (en) 1983-06-29
FI72534C (en) 1987-06-08
AT379828B (en) 1986-03-10
SE8302126D0 (en) 1983-04-15
NO157825C (en) 1988-05-25

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