SE8103678L - PROCEDURE FOR INHIBITING GROWTH OF PROTOCOS - Google Patents

PROCEDURE FOR INHIBITING GROWTH OF PROTOCOS

Info

Publication number
SE8103678L
SE8103678L SE8103678A SE8103678A SE8103678L SE 8103678 L SE8103678 L SE 8103678L SE 8103678 A SE8103678 A SE 8103678A SE 8103678 A SE8103678 A SE 8103678A SE 8103678 L SE8103678 L SE 8103678L
Authority
SE
Sweden
Prior art keywords
protocos
procedure
inhibiting growth
carboxy
hydrogen
Prior art date
Application number
SE8103678A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE460517B (en
Inventor
A Sjoerdsma
P P Mccann
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of SE8103678L publication Critical patent/SE8103678L/en
Publication of SE460517B publication Critical patent/SE460517B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/132Heterocyclic compounds containing only one nitrogen as hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)

Abstract

Compounds of the formula <IMAGE> wherein R1 is hydrogen or carboxy; Y is -CH2F, -CHF2, -CF3 or -C IDENTICAL CH; and Z is -(CH2)3-NH2, -CH(CH)3- (CH2)2-NH2 or -CH=CH-CH2- NH2; with the proviso that, when R1 is hydrogen, Z is -CH(CH3)-(CH2)2- NH2 and Y is not -CF3; or a lactam thereof when R1 is carboxy; and their salts, are useful in inhibiting the growth of protozoa. They may be administered to animals, e.g. in their drinking water, and, if desired, together with an antiprotozoal agent.
SE8103678A 1980-06-16 1981-06-11 USE OF A COMPOSITION FOR THE PREPARATION OF A MEDICINE FOR THE TREATMENT OF INFECTIONS CAUSED BY TRYPANOSOMA BRUCEI SE460517B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15997380A 1980-06-16 1980-06-16

Publications (2)

Publication Number Publication Date
SE8103678L true SE8103678L (en) 1981-12-17
SE460517B SE460517B (en) 1989-10-23

Family

ID=22574910

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8103678A SE460517B (en) 1980-06-16 1981-06-11 USE OF A COMPOSITION FOR THE PREPARATION OF A MEDICINE FOR THE TREATMENT OF INFECTIONS CAUSED BY TRYPANOSOMA BRUCEI

Country Status (17)

Country Link
JP (1) JPS5731613A (en)
AT (1) AT377180B (en)
AU (1) AU544990B2 (en)
BE (1) BE889230A (en)
CA (1) CA1174603A (en)
CH (1) CH651206A5 (en)
DE (2) DE3123295A1 (en)
FR (1) FR2484255A1 (en)
GB (1) GB2078735B (en)
IE (1) IE51300B1 (en)
IL (1) IL63087A (en)
IT (1) IT1171380B (en)
NL (1) NL194153C (en)
NZ (1) NZ197394A (en)
PH (1) PH16634A (en)
SE (1) SE460517B (en)
ZA (1) ZA813953B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58123555U (en) * 1982-02-17 1983-08-23 三菱電機株式会社 In-line electron gun assembly equipment
NL8400927A (en) * 1984-03-23 1985-10-16 Philips Nv DEVICE AND METHOD FOR MOUNTING AN INTEGRATED ELECTRON CANNON SYSTEM.
DE3421384A1 (en) * 1984-06-08 1985-12-12 Standard Elektrik Lorenz Ag, 7000 Stuttgart DEVICE FOR ASSEMBLING ELECTRONIC RADIATOR GENERATORS
JPS62148462A (en) * 1985-12-19 1987-07-02 メレルダウフア−マス−テイカルズ インコ−ポレ−テツド Novel method of controlling growth of protozoa
ATE77367T1 (en) * 1988-02-05 1992-07-15 Merrell Dow Pharma 5-SUBSTITUTED ORNITHINE DERIVATIVES.
US5455234A (en) * 1994-03-16 1995-10-03 Ahluwalia; Gurpreet S. Inhibition of hair growth

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ187377A (en) * 1977-06-01 1981-05-15 Merck & Co Inc A-amino-a-substituted alkyl-a-fluoromethylacetic acids
US4139563A (en) * 1977-07-01 1979-02-13 Merrell Toraude Et Compagnie α-ACETYLENIC DERIVATIVES OF AMINES
US4182891A (en) * 1977-07-01 1980-01-08 Merrell Toraude Et Compagnie α-Acetylenic derivatives of α-amino acids
US4088667A (en) * 1977-07-01 1978-05-09 Merrell Toraude Et Compagnie Lower alkyl 2-tri-(lower)alkylsilylacetylene-N-carbethoxyglycinates and process for using same
CA1121375A (en) * 1977-07-01 1982-04-06 Brian W. Metcalf Derivatives of amines and amino acids
CA1091661A (en) 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4134918A (en) * 1977-09-06 1979-01-16 Merrell Toraude Et Compagnie Alpha-halomethyl derivatives of amines

Also Published As

Publication number Publication date
PH16634A (en) 1983-12-05
IL63087A (en) 1984-10-31
JPS5731613A (en) 1982-02-20
GB2078735A (en) 1982-01-13
CA1174603A (en) 1984-09-18
FR2484255B1 (en) 1984-12-14
IT1171380B (en) 1987-06-10
IT8148684A0 (en) 1981-06-15
FR2484255A1 (en) 1981-12-18
CH651206A5 (en) 1985-09-13
GB2078735B (en) 1985-05-15
BE889230A (en) 1981-12-15
DE3123295A1 (en) 1982-04-29
DE3123295C2 (en) 1990-07-12
IE51300B1 (en) 1986-11-26
ZA813953B (en) 1982-06-30
NL194153B (en) 2001-04-02
AT377180B (en) 1985-02-25
AU544990B2 (en) 1985-06-27
AU7165481A (en) 1981-12-24
NZ197394A (en) 1984-09-28
NL8102863A (en) 1982-01-18
NL194153C (en) 2001-08-03
JPH0432052B2 (en) 1992-05-28
DE3153623C2 (en) 1991-06-27
SE460517B (en) 1989-10-23
IE811308L (en) 1981-12-16
ATA266581A (en) 1984-07-15

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