SE8102776L - SEPARATIONSFORFARANDE - Google Patents

SEPARATIONSFORFARANDE

Info

Publication number
SE8102776L
SE8102776L SE8102776A SE8102776A SE8102776L SE 8102776 L SE8102776 L SE 8102776L SE 8102776 A SE8102776 A SE 8102776A SE 8102776 A SE8102776 A SE 8102776A SE 8102776 L SE8102776 L SE 8102776L
Authority
SE
Sweden
Prior art keywords
blood sample
chamber
platelets
saline
separation
Prior art date
Application number
SE8102776A
Other languages
Swedish (sv)
Inventor
M D Persidsky
N-S Ling
Original Assignee
Inst Of Medical Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/146,461 external-priority patent/US4269718A/en
Priority claimed from US06/146,462 external-priority patent/US4268393A/en
Application filed by Inst Of Medical Sciences filed Critical Inst Of Medical Sciences
Publication of SE8102776L publication Critical patent/SE8102776L/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D43/00—Separating particles from liquids, or liquids from solids, otherwise than by sedimentation or filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber

Abstract

This invention relates to a method and apparatus for the separation of finely divided solid particles dissimilar in size and/or density in a liquid, such as platelets and other blood cells in a blood sample. The separation of, for instance, platelets is accomplished by subjecting the blood sample to centrifugal force in a rotatable chamber while displacing the platelets from the blood sample by injecting a relatively small volume of saline into the centrifugally outer end of the chamber. In a preferred apparatus, the saline is injected via a port (15) into the blood sample by driving a chamber (14) of supporting the blood sample into a saline filled cavity under the influence of centrifugal force. The chamber (14) is formed in a piston (12) slidable in a cylinder (13) which in use is placed in the swinging bucket of a centrifuge. <IMAGE>
SE8102776A 1980-05-05 1981-05-04 SEPARATIONSFORFARANDE SE8102776L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/146,461 US4269718A (en) 1980-05-05 1980-05-05 Process and device for centrifugal separation of platelets
US06/146,462 US4268393A (en) 1980-05-05 1980-05-05 Apparatus for centrifugal separation of platelet-rich plasma

Publications (1)

Publication Number Publication Date
SE8102776L true SE8102776L (en) 1981-11-06

Family

ID=26843938

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8102776A SE8102776L (en) 1980-05-05 1981-05-04 SEPARATIONSFORFARANDE

Country Status (5)

Country Link
CA (1) CA1185218A (en)
DE (1) DE3117710A1 (en)
FR (1) FR2481614A1 (en)
GB (1) GB2075376B (en)
SE (1) SE8102776L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1311989B1 (en) 1999-03-30 2002-03-22 Giammaria Sitar PROCEDURE FOR ISOLATING FETAL CELLS PRESENT IN THE PERIPHERAL BLOOD.
IT201800009295A1 (en) 2018-10-09 2020-04-09 Sacmi Cooperativa Mecc Imola Societa' Cooperativa APPARATUS AND METHOD FOR WORKING CUPS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3800947A (en) * 1971-07-16 1974-04-02 P Smith Reagent tube and centrifugally operated solid-liquid separating device
US4057499A (en) * 1973-03-09 1977-11-08 Buono Frank S Apparatus and method for separation of blood
US3960727A (en) * 1974-08-09 1976-06-01 Hochstrasser Harry T Apparatus and method for isolating soluble blood components
US3986506A (en) * 1974-09-03 1976-10-19 Baxter Travenol Laboratories, Inc. Apparatus for separation of cryoprecipitate from blood plasma and method
US4007871A (en) * 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container

Also Published As

Publication number Publication date
DE3117710A1 (en) 1982-04-08
CA1185218A (en) 1985-04-09
FR2481614A1 (en) 1981-11-06
GB2075376A (en) 1981-11-18
FR2481614B1 (en) 1985-03-29
GB2075376B (en) 1983-09-21

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