SE8006870L - DISUBSTITUTED BENZOYL-ALFA-PHENOXIAL CANOYL ESTERS - Google Patents
DISUBSTITUTED BENZOYL-ALFA-PHENOXIAL CANOYL ESTERSInfo
- Publication number
- SE8006870L SE8006870L SE8006870A SE8006870A SE8006870L SE 8006870 L SE8006870 L SE 8006870L SE 8006870 A SE8006870 A SE 8006870A SE 8006870 A SE8006870 A SE 8006870A SE 8006870 L SE8006870 L SE 8006870L
- Authority
- SE
- Sweden
- Prior art keywords
- loweralkyl
- hydrogen
- image
- carbon atoms
- phenoxial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Described are compounds of the formula <IMAGE> wherein R1 is <IMAGE> wherein R5 and R6 are hydrogen, loweralkyl or alkylene of 4 or 5 carbon atoms, R2 is hydrogen, halo, haloloweralkyl, loweralkyl, loweralkoxy, loweralkylthio or <IMAGE> wherein R5 and R6 are as previously defined, R3 is hydroxy, alkoxy, branched alkoxy, adamantyloxy, morpholino, amino or amino substituted by loweralkyl or alkylene of 4 or 5 carbon atoms, R4 is hydrogen or loweralkyl, and X1 and X2 are hydrogen, loweralkyl, halo or when substituted on adjacent carbon atoms of the benzene ring form a 1,3-butadienylene linkage, with the proviso that X1 and X2 are not both hydrogen, and pharmaceutically acceptable salts thereof, the compounds are effective as diuretic agents in increasing urinary excretion.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8300879A | 1979-10-09 | 1979-10-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE8006870L true SE8006870L (en) | 1981-04-10 |
Family
ID=22175236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8006870A SE8006870L (en) | 1979-10-09 | 1980-10-01 | DISUBSTITUTED BENZOYL-ALFA-PHENOXIAL CANOYL ESTERS |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS56115746A (en) |
AR (1) | AR228139A1 (en) |
AU (1) | AU538125B2 (en) |
BE (1) | BE885586A (en) |
CA (1) | CA1149803A (en) |
CH (1) | CH646135A5 (en) |
DE (1) | DE3038011A1 (en) |
ES (1) | ES495751A0 (en) |
FR (1) | FR2467193A1 (en) |
GB (1) | GB2060628B (en) |
GR (1) | GR70775B (en) |
IT (1) | IT1132929B (en) |
NL (1) | NL8005566A (en) |
PH (1) | PH16254A (en) |
SE (1) | SE8006870L (en) |
ZA (1) | ZA805738B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4435422A (en) * | 1982-09-15 | 1984-03-06 | Abbott Laboratories | 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions |
GB2216515A (en) * | 1988-03-04 | 1989-10-11 | Nippon Shinyaku Co Ltd | Acylphenol derivatives |
US5883294A (en) * | 1997-06-18 | 1999-03-16 | The Regeants Of The University Of California | Selective thyroid hormone analogs |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5195049A (en) * | 1975-02-12 | 1976-08-20 | * **********so*****no***tsu*****************************************ni*no | |
US4058559A (en) | 1975-09-24 | 1977-11-15 | Abbott Laboratories | 4-Aroyl-substituted phenoxy acetic acids |
-
1980
- 1980-09-16 CA CA000360297A patent/CA1149803A/en not_active Expired
- 1980-09-17 ZA ZA00805738A patent/ZA805738B/en unknown
- 1980-09-18 GB GB8030259A patent/GB2060628B/en not_active Expired
- 1980-09-18 PH PH24598A patent/PH16254A/en unknown
- 1980-09-23 AU AU62626/80A patent/AU538125B2/en not_active Ceased
- 1980-10-01 SE SE8006870A patent/SE8006870L/en not_active Application Discontinuation
- 1980-10-06 GR GR63059A patent/GR70775B/el unknown
- 1980-10-07 AR AR282803A patent/AR228139A1/en active
- 1980-10-08 DE DE19803038011 patent/DE3038011A1/en not_active Withdrawn
- 1980-10-08 NL NL8005566A patent/NL8005566A/en not_active Application Discontinuation
- 1980-10-08 FR FR8021501A patent/FR2467193A1/en active Granted
- 1980-10-08 CH CH752680A patent/CH646135A5/en not_active IP Right Cessation
- 1980-10-08 BE BE0/202374A patent/BE885586A/en not_active IP Right Cessation
- 1980-10-08 IT IT25204/80A patent/IT1132929B/en active
- 1980-10-08 ES ES495751A patent/ES495751A0/en active Granted
- 1980-10-09 JP JP14064780A patent/JPS56115746A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU6262680A (en) | 1981-04-16 |
FR2467193A1 (en) | 1981-04-17 |
GB2060628A (en) | 1981-05-07 |
ZA805738B (en) | 1981-09-30 |
AU538125B2 (en) | 1984-08-02 |
GR70775B (en) | 1983-03-22 |
CA1149803A (en) | 1983-07-12 |
IT8025204A0 (en) | 1980-10-08 |
ES8201119A1 (en) | 1981-12-01 |
NL8005566A (en) | 1981-04-13 |
ES495751A0 (en) | 1981-12-01 |
GB2060628B (en) | 1984-01-11 |
AR228139A1 (en) | 1983-01-31 |
IT1132929B (en) | 1986-07-09 |
FR2467193B1 (en) | 1983-06-10 |
DE3038011A1 (en) | 1981-04-23 |
BE885586A (en) | 1981-04-08 |
CH646135A5 (en) | 1984-11-15 |
JPS56115746A (en) | 1981-09-11 |
PH16254A (en) | 1983-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 8006870-3 Effective date: 19861226 Format of ref document f/p: F |