SE8003761L - PROCEDURE FOR PREPARING A MODIFIED CRYSTAL FORM OF FLUNISOLIDE - Google Patents

PROCEDURE FOR PREPARING A MODIFIED CRYSTAL FORM OF FLUNISOLIDE

Info

Publication number
SE8003761L
SE8003761L SE8003761A SE8003761A SE8003761L SE 8003761 L SE8003761 L SE 8003761L SE 8003761 A SE8003761 A SE 8003761A SE 8003761 A SE8003761 A SE 8003761A SE 8003761 L SE8003761 L SE 8003761L
Authority
SE
Sweden
Prior art keywords
flunisolide
preparing
procedure
crystal form
modified crystal
Prior art date
Application number
SE8003761A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE431549B (en
Inventor
R E Jones
J A Smithers
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Corp filed Critical Syntex Corp
Publication of SE8003761L publication Critical patent/SE8003761L/en
Publication of SE431549B publication Critical patent/SE431549B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A unique crystalline form of flunisolide is prepared by crystallizing flunisolide from a solution thereof in an alkanol of three or four carbon atoms, e.g. n-butanol, containing 0.2 to 5%, preferably 1.0 to 4.0% by volume water.
SE8003761A 1979-05-21 1980-05-20 PROCEDURE FOR PREPARING A CRYSTAL INFORMATION OF FLUNISOLIDE (6ALFA-FLUOR-11BETA, 21-DIHYDROXY-16ALFA, 17ALFA-ISOPROPYLIDENIDIOXIPREGNA-1,4-DIENE-3,20-DION) SE431549B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4083079A 1979-05-21 1979-05-21

Publications (2)

Publication Number Publication Date
SE8003761L true SE8003761L (en) 1980-11-22
SE431549B SE431549B (en) 1984-02-13

Family

ID=21913206

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8003761A SE431549B (en) 1979-05-21 1980-05-20 PROCEDURE FOR PREPARING A CRYSTAL INFORMATION OF FLUNISOLIDE (6ALFA-FLUOR-11BETA, 21-DIHYDROXY-16ALFA, 17ALFA-ISOPROPYLIDENIDIOXIPREGNA-1,4-DIENE-3,20-DION)

Country Status (17)

Country Link
JP (1) JPS55154997A (en)
AU (1) AU532084B2 (en)
BE (1) BE883381A (en)
CA (1) CA1153761A (en)
CH (1) CH643567A5 (en)
DE (1) DE3019250C2 (en)
DK (1) DK162530C (en)
FR (1) FR2457303A1 (en)
GB (1) GB2052506B (en)
HK (1) HK40784A (en)
IL (1) IL60128A (en)
IT (1) IT1133092B (en)
MY (1) MY8500694A (en)
NL (1) NL189201C (en)
NZ (1) NZ193778A (en)
SE (1) SE431549B (en)
SG (1) SG37585G (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1121513B (en) * 1979-05-28 1986-04-02 Chiesi Farma Spa PROCESS FOR THE CONVERSION OF ANTI-INFLAMMATORY STEROID UMO IN A SUSCEPTIBLE FORM OF BEING ADMINISTERED AS AN AEROSOL

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX3864E (en) * 1975-05-27 1981-08-26 Syntex Corp A PROCESS TO PREPARE THE CRYSTALLINE COMPOUND 6-FLUIRO-11B 21-DIHIROXI-16 17-ISOPROPILIDENDIOXIPREGNA-1 4-DIEN-3 20-DIONA

Also Published As

Publication number Publication date
JPS6258360B2 (en) 1987-12-05
NZ193778A (en) 1982-03-16
IT1133092B (en) 1986-07-09
MY8500694A (en) 1985-12-31
JPS55154997A (en) 1980-12-02
DK219280A (en) 1980-11-22
AU532084B2 (en) 1983-09-15
HK40784A (en) 1984-05-18
GB2052506B (en) 1983-01-19
NL8002902A (en) 1980-11-25
FR2457303A1 (en) 1980-12-19
FR2457303B1 (en) 1983-05-13
CH643567A5 (en) 1984-06-15
SG37585G (en) 1986-01-17
CA1153761A (en) 1983-09-13
AU5856680A (en) 1980-11-27
IL60128A (en) 1984-01-31
GB2052506A (en) 1981-01-28
SE431549B (en) 1984-02-13
IL60128A0 (en) 1980-07-31
DK162530C (en) 1992-03-30
DK162530B (en) 1991-11-11
IT8067791A0 (en) 1980-05-20
DE3019250C2 (en) 1982-11-11
NL189201B (en) 1992-09-01
NL189201C (en) 1993-02-01
DE3019250A1 (en) 1980-12-04
BE883381A (en) 1980-11-20

Similar Documents

Publication Publication Date Title
RO77525A (en) PROCESS FOR THE PREPARATION OF ADDITION SALTS OF S-ADENOZYL-L-METHIONINE
FR2325651A1 (en) PROCESS FOR THE PREPARATION OF ORGANOSILICIC COMPOUNDS CONTAINING SULFUR
NO144636C (en) PROCEDURE FOR THE PREPARATION OF METANOL ENCELLE PROTEIN BY CULTIVATING MICRO-ORGANISMS IN A FOAM CULTURE
HK51782A (en) Fluorphenyl-trans-cyclohexanes process for their preparation liquid crystalline dielectrics containing them and displaying means
RO78632A (en) PROCESS FOR THE PREPARATION OF INDANILE DERIVATIVES
DE2860102D1 (en) Process for the preparation of 2-butene-1-ol compounds by isomerization of the corresponding 3-butene-1-ol compounds
NO791477L (en) PROCEDURE FOR PREPARING NEW LACTAM-N-ACTIC ACIDS AND THEIR AMIDES
PT69185B (en) PROCESS FOR PREPARING OF SUBSTITUTED PYRIDAZONE WITH HERBICIDAL EFFECT
MY8000062A (en) Improvements relating to the growing of seedlings
ES8400752A1 (en) Derivatives of cyclophosphamide, process for their preparation and their use.
SE8003761L (en) PROCEDURE FOR PREPARING A MODIFIED CRYSTAL FORM OF FLUNISOLIDE
JPS567799A (en) Novel pseudotrisaccharide* its manufacture and use as medicine
HUT47091A (en) Process for producing tetrahydrobenzthiazols
SE8803765D0 (en) NEW ISOPOLYPEPTIDES AND PROCEDURES FOR THE PREPARATION OF THE SAME
IT1112051B (en) PROCEDURE FOR ISOLATION OF PURE L-CISTINE
JPS54114482A (en) Preparing single crystal of 3 to 4 group compounds
FR2275441A1 (en) PROCESS FOR THE PREPARATION OF ACETOXYBUTANAL
ES430420A1 (en) Phenylpropanolamines
FR2282707A1 (en) PROCESS FOR PREPARING THE CASE OF AN ELECTROLYTIC CONDENSER
RO71949A (en) PROCESS FOR CULTIVATION OF BAZIDIOMICETES
JPS5683489A (en) New antibiotic pa-39504-x1 and it preparation
DE3060552D1 (en) Process for the preparation of asymmetrical thioindigo compounds as well as thionaphthenones as such
FR2290947A1 (en) PROCESS FOR THE PREPARATION OF GALLIUM ARSENIDE SINGLE CRYSTALS
FR2360639A1 (en) PREPARATION OF AN AZOMETHINIC PIGMENT
NO137069C (en) PROCEDURES FOR DETERMINATION OF SEEDABILITY OR GROWTH OF SEEDS PRIOR TO GROWING

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8003761-7

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8003761-7

Format of ref document f/p: F