SE8000467L - PROCEDURE FOR THERMAL STABILIZATION - Google Patents

PROCEDURE FOR THERMAL STABILIZATION

Info

Publication number
SE8000467L
SE8000467L SE8000467A SE8000467A SE8000467L SE 8000467 L SE8000467 L SE 8000467L SE 8000467 A SE8000467 A SE 8000467A SE 8000467 A SE8000467 A SE 8000467A SE 8000467 L SE8000467 L SE 8000467L
Authority
SE
Sweden
Prior art keywords
coating
capsules
soluble
active agent
film
Prior art date
Application number
SE8000467A
Other languages
Unknown language ( )
Swedish (sv)
Inventor
P Schmidt
J Prochazka
I Bohrer
Original Assignee
Heumann Ludwig & Co Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig & Co Gmbh filed Critical Heumann Ludwig & Co Gmbh
Publication of SE8000467L publication Critical patent/SE8000467L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Abstract

The thermal and dimensional stability of soft gelatin capsules containing a pharmaceutically active agent incorporated in the gelatin is improved by coating the capsules with a film coating of a film-forming polymer which is soluble or swellable in water and soluble in organic solvents, e.g. cellulose esters, cellulose ethers, polyvinyl pyrrolidone, acrylate/methacrylate co-polymers, polyethylene glycols, and zein. The capsules have a small air bubble as the core, and are usually for chewing or sucking to provide a prolonged local oral release of the active agent. The film coating may be applied by spraying on a solution of the polymer in organic solvent, and then drying the coating.
SE8000467A 1979-02-01 1980-01-21 PROCEDURE FOR THERMAL STABILIZATION SE8000467L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2903778A DE2903778C2 (en) 1979-02-01 1979-02-01 Use of hydroxypropylmethylcellulose for coating soft gelatine buccal capsules containing the pharmaceutical active substance in the shell

Publications (1)

Publication Number Publication Date
SE8000467L true SE8000467L (en) 1980-08-02

Family

ID=6061893

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8000467A SE8000467L (en) 1979-02-01 1980-01-21 PROCEDURE FOR THERMAL STABILIZATION

Country Status (20)

Country Link
JP (1) JPS55104212A (en)
AR (1) AR223202A1 (en)
AT (1) AT372607B (en)
AU (1) AU5488780A (en)
BE (1) BE881462A (en)
CA (1) CA1142084A (en)
CS (1) CS222299B2 (en)
DD (1) DD148584A5 (en)
DE (1) DE2903778C2 (en)
DK (1) DK42880A (en)
FR (1) FR2447720A1 (en)
GB (1) GB2043442A (en)
GR (1) GR70084B (en)
HU (1) HU183053B (en)
IL (1) IL59137A (en)
IT (1) IT8067057A0 (en)
NL (1) NL8000634A (en)
PT (1) PT70706A (en)
SE (1) SE8000467L (en)
ZA (1) ZA80382B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5953410A (en) * 1982-09-20 1984-03-28 Fujisawa Pharmaceut Co Ltd Novel soft capsule agent
CH666405A5 (en) * 1985-06-24 1988-07-29 Ciba Geigy Ag SOLID, DURABLE PHARMACEUTICAL FORMS WITH ELASTIC FILM COVER.
US5068110A (en) * 1987-09-29 1991-11-26 Warner-Lambert Company Stabilization of enteric coated dosage form
JPH02205A (en) * 1987-11-09 1990-01-05 Taisho Pharmaceut Co Ltd Perfume-containing coating agent for soft capsule
FR2698560B1 (en) * 1992-11-30 1995-02-03 Virbac Laboratoires Stabilized powdery active ingredients, compositions containing them, process for obtaining them and their applications.
US6030641A (en) * 1997-06-03 2000-02-29 Uni Colloid Kabushiki Kaisha Sustained release capsule and method for preparing the same
US20070053972A1 (en) * 2005-09-08 2007-03-08 Cadbury Adams Usa Llc. Gelatin capsules containing actives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE695234C (en) * 1937-10-30 1940-08-20 Schering Ag Process for the protection of solid, crystalline fragments
CH476499A (en) * 1964-12-31 1969-08-15 Ciba Geigy Mixture for coating rectal capsules
DE1617671C3 (en) * 1967-03-07 1980-07-03 A. Nattermann & Cie Gmbh, 5000 Koeln Soft gelatine capsules with increased thermal stability
DE1767425B2 (en) * 1968-05-09 1973-05-17 R P Scherer GmbH, 6930 Eberbach PROCESS FOR THE MANUFACTURING OF GELATIN CAPSULES RESISTANT TO MAGIC JUICE
BE757715A (en) * 1969-10-21 1971-04-20 Ciba Geigy COATING FOR GELATIN CAPSULES AND PROCESS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
DE2903778A1 (en) 1980-08-07
AR223202A1 (en) 1981-07-31
BE881462A (en) 1980-05-16
DD148584A5 (en) 1981-06-03
GB2043442A (en) 1980-10-08
ZA80382B (en) 1981-01-28
GR70084B (en) 1982-07-30
JPS55104212A (en) 1980-08-09
HU183053B (en) 1984-04-28
AU5488780A (en) 1980-08-07
CA1142084A (en) 1983-03-01
CS222299B2 (en) 1983-06-24
FR2447720A1 (en) 1980-08-29
IT8067057A0 (en) 1980-01-16
DE2903778C2 (en) 1982-06-03
DK42880A (en) 1980-08-02
PT70706A (en) 1980-02-01
AT372607B (en) 1983-10-25
ATA19280A (en) 1983-03-15
IL59137A (en) 1983-10-31
NL8000634A (en) 1980-08-05

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