SE7713779L - NEW PHENYL DERIVATIVES - Google Patents
NEW PHENYL DERIVATIVESInfo
- Publication number
- SE7713779L SE7713779L SE7713779A SE7713779A SE7713779L SE 7713779 L SE7713779 L SE 7713779L SE 7713779 A SE7713779 A SE 7713779A SE 7713779 A SE7713779 A SE 7713779A SE 7713779 L SE7713779 L SE 7713779L
- Authority
- SE
- Sweden
- Prior art keywords
- lower alkyl
- phenyl derivatives
- integer
- hydrogen
- new phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
There are described levo-rotary 3-phenoxy morphinan derivatives of the general formula wherein R is halogen, nitro, lower alkyl, lower alkoxy, hydroxy or hydrogen; R1 is hydrogen, lower alkyl, lower alkenyl, -CH2(CH2)pR2 or -?-(CH2)p-R2; R2 is heteroaromatic, axomatic or cyclo-lower alkyl; p is an integer from 0 to 3; and n is an integer from 1 to 5 and pharmaceutically acceptable acid addition salts which are useful as analgesic and/or narcotic antagonists.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74802276A | 1976-12-06 | 1976-12-06 | |
| US05/811,233 US4113729A (en) | 1976-12-06 | 1977-06-29 | 3-Phenoxymorphinans and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7713779L true SE7713779L (en) | 1978-06-07 |
Family
ID=27114858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7713779A SE7713779L (en) | 1976-12-06 | 1977-12-05 | NEW PHENYL DERIVATIVES |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5392776A (en) |
| AR (1) | AR219510A1 (en) |
| AT (1) | AT364826B (en) |
| AU (1) | AU514827B2 (en) |
| CA (1) | CA1088935A (en) |
| DE (1) | DE2754062A1 (en) |
| DK (1) | DK540977A (en) |
| ES (3) | ES464751A1 (en) |
| FI (1) | FI773636A (en) |
| FR (1) | FR2372808A1 (en) |
| GB (1) | GB1589792A (en) |
| HU (1) | HU177640B (en) |
| IE (1) | IE46003B1 (en) |
| IL (1) | IL53532A (en) |
| IT (1) | IT1143727B (en) |
| LU (1) | LU78638A1 (en) |
| MC (1) | MC1172A1 (en) |
| NL (1) | NL7713432A (en) |
| NO (1) | NO774155L (en) |
| NZ (1) | NZ185860A (en) |
| PT (1) | PT67363B (en) |
| SE (1) | SE7713779L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4247697A (en) * | 1979-09-10 | 1981-01-27 | Hoffmann-La Roche Inc. | 3-Phenoxy morphinans and their derivatives |
| TW264473B (en) * | 1993-01-06 | 1995-12-01 | Hoffmann La Roche |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH560194A5 (en) * | 1967-08-25 | 1975-03-27 | Hoffmann La Roche | |
| JPS493961B1 (en) * | 1969-06-24 | 1974-01-29 |
-
1977
- 1977-11-30 FI FI773636A patent/FI773636A/en not_active Application Discontinuation
- 1977-12-05 LU LU7778638A patent/LU78638A1/xx unknown
- 1977-12-05 PT PT67363A patent/PT67363B/en unknown
- 1977-12-05 CA CA292,433A patent/CA1088935A/en not_active Expired
- 1977-12-05 MC MC771272A patent/MC1172A1/en unknown
- 1977-12-05 AT AT0869277A patent/AT364826B/en not_active IP Right Cessation
- 1977-12-05 SE SE7713779A patent/SE7713779L/en not_active Application Discontinuation
- 1977-12-05 IL IL53532A patent/IL53532A/en unknown
- 1977-12-05 NL NL7713432A patent/NL7713432A/en not_active Application Discontinuation
- 1977-12-05 ES ES464751A patent/ES464751A1/en not_active Expired
- 1977-12-05 IE IE2468/77A patent/IE46003B1/en unknown
- 1977-12-05 GB GB50495/77A patent/GB1589792A/en not_active Expired
- 1977-12-05 DK DK540977A patent/DK540977A/en unknown
- 1977-12-05 NO NO774155A patent/NO774155L/en unknown
- 1977-12-05 DE DE19772754062 patent/DE2754062A1/en not_active Withdrawn
- 1977-12-05 HU HU77HO2029A patent/HU177640B/en unknown
- 1977-12-05 JP JP14520377A patent/JPS5392776A/en active Pending
- 1977-12-05 NZ NZ185860A patent/NZ185860A/en unknown
- 1977-12-06 IT IT30510/77A patent/IT1143727B/en active
- 1977-12-06 AU AU31264/77A patent/AU514827B2/en not_active Expired
- 1977-12-06 AR AR270265A patent/AR219510A1/en active
- 1977-12-06 FR FR7736745A patent/FR2372808A1/en active Granted
-
1978
- 1978-08-16 ES ES472573A patent/ES472573A1/en not_active Expired
- 1978-08-16 ES ES472572A patent/ES472572A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI773636A (en) | 1978-06-07 |
| NO774155L (en) | 1978-06-07 |
| AU514827B2 (en) | 1981-02-26 |
| FR2372808B1 (en) | 1981-07-10 |
| IL53532A (en) | 1981-09-13 |
| AT364826B (en) | 1981-11-25 |
| MC1172A1 (en) | 1978-09-25 |
| IT1143727B (en) | 1986-10-22 |
| AU3126477A (en) | 1979-06-14 |
| HU177640B (en) | 1981-11-28 |
| ES472572A1 (en) | 1979-02-16 |
| NL7713432A (en) | 1978-06-08 |
| NZ185860A (en) | 1980-10-24 |
| PT67363B (en) | 1979-12-17 |
| ES464751A1 (en) | 1978-12-16 |
| JPS5392776A (en) | 1978-08-15 |
| FR2372808A1 (en) | 1978-06-30 |
| AR219510A1 (en) | 1980-08-29 |
| IL53532A0 (en) | 1978-03-10 |
| ATA869277A (en) | 1981-04-15 |
| GB1589792A (en) | 1981-05-20 |
| DK540977A (en) | 1978-06-07 |
| ES472573A1 (en) | 1979-02-16 |
| LU78638A1 (en) | 1979-02-02 |
| IE46003B1 (en) | 1983-01-26 |
| DE2754062A1 (en) | 1978-06-08 |
| PT67363A (en) | 1978-01-01 |
| IE46003L (en) | 1978-06-06 |
| CA1088935A (en) | 1980-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7713779-2 |