SE7713016L - PROCEDURE FOR PREPARING NEW DERIVATIVES BETA-1,3-GLUCANE - Google Patents
PROCEDURE FOR PREPARING NEW DERIVATIVES BETA-1,3-GLUCANEInfo
- Publication number
- SE7713016L SE7713016L SE7713016A SE7713016A SE7713016L SE 7713016 L SE7713016 L SE 7713016L SE 7713016 A SE7713016 A SE 7713016A SE 7713016 A SE7713016 A SE 7713016A SE 7713016 L SE7713016 L SE 7713016L
- Authority
- SE
- Sweden
- Prior art keywords
- glucan
- tumors
- glucane
- procedure
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Abstract
It has been found that water-insoluble, thermogelable beta -1,3-glucan produced by microorganisms, lower polymers obtainable upon partial hydrolysis of the glucan or, carboxymethylated derivatives of said glucan or of said lower polymers are useful for inhibiting growth of tumors in a warm-blooded animal. The inhibitory activity against various tumors of these polysaccharides is very strong and significant whenever administered to warm-blooded animals from the early to very late stage of tumor progression or even when administered prior to plantation of tumors. The carboxymethylated derivatives above-mentioned are novel water-soluble compounds which can be produced by carboxymethylation of said glucan and partial hydrolyzate thereof.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13914376A JPS5366442A (en) | 1976-11-18 | 1976-11-18 | Antitumors |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7713016L true SE7713016L (en) | 1978-05-19 |
SE432939B SE432939B (en) | 1984-04-30 |
Family
ID=15238550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7713016A SE432939B (en) | 1976-11-18 | 1977-11-17 | PROCEDURE FOR PREPARING NEW DERIVATIVES OF BETA-1,3-GLUCAN WITH PHARMACOLOGICAL EFFECT |
Country Status (12)
Country | Link |
---|---|
US (1) | US4454315A (en) |
JP (1) | JPS5366442A (en) |
BE (1) | BE860885A (en) |
CA (1) | CA1100951A (en) |
CH (1) | CH634855A5 (en) |
DE (1) | DE2751570A1 (en) |
DK (1) | DK510177A (en) |
FR (2) | FR2421617A1 (en) |
GB (1) | GB1595596A (en) |
NL (1) | NL7712764A (en) |
SE (1) | SE432939B (en) |
SU (1) | SU1024011A3 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8404299D0 (en) * | 1984-02-18 | 1984-03-21 | Milner Research Ireland Ltd | Peritoneal dialysis |
US4774093A (en) * | 1985-06-25 | 1988-09-27 | Fmc Corporation | Polysaccharide compositions, preparation and uses |
JPH0653764B2 (en) * | 1985-07-31 | 1994-07-20 | 三井東圧化学株式会社 | Method for producing monosialoganglioside |
JPH0692441B2 (en) * | 1986-03-03 | 1994-11-16 | 株式会社林原生物化学研究所 | β-D-glucan, production method and use thereof |
JPH02124902A (en) * | 1988-07-21 | 1990-05-14 | Takeda Chem Ind Ltd | Blood coagulation inhibitor |
KR0141685B1 (en) * | 1988-09-01 | 1998-07-01 | 야마따니 와따루 | Limulus amoebocyte lysate g-factor activation |
CA1328074C (en) * | 1988-09-01 | 1994-03-29 | Shigenori Tanaka | Horseshoe crab amebocyte lysate factor g inhibitor |
DE3929355A1 (en) * | 1989-09-04 | 1991-03-07 | Boehringer Mannheim Gmbh | PROCESS FOR SPECIFIC DETERMINATION OF PANCREAS (ALPHA) AMYLASE |
US5227372A (en) * | 1990-03-07 | 1993-07-13 | Children's Medical Center Corporation | Method for retaining ophthalmological agents in ocular tissues |
JP3122454B2 (en) * | 1990-09-27 | 2001-01-09 | 生化学工業株式会社 | Preparation of horseshoe crab, amebosite lysate |
ES2117664T3 (en) * | 1991-02-21 | 1998-08-16 | Drug Delivery System Inst Ltd | CARBOXIMETILMANOGLUCANOS AND DERIVATIVES THEREOF. |
US5519009A (en) * | 1993-10-01 | 1996-05-21 | Donzis; Byron A. | Solubilized yeast glucan |
US5760213A (en) * | 1995-06-05 | 1998-06-02 | Tayca Corporation | Immunoactivating agent |
EP0775491A4 (en) * | 1995-06-22 | 1998-05-20 | Tayca Corp | Immunopotentiator |
EP1197216B1 (en) * | 1996-07-19 | 2004-06-23 | Mibelle AG Cosmetics | Pharmaceutical or cosmetic composition containing polyglucan ether derivatives |
ATE322903T1 (en) * | 1999-07-09 | 2006-04-15 | Sun Farm Corp | DIETARY SUPPLEMENT FOR TREATING MALIGNANTS AND VIRUS INFECTIONS AND IMPROVING IMMUNE FUNCTION |
AU2001279796A1 (en) * | 2000-08-03 | 2002-02-18 | Abac R & D Gmbh | Isolation of glucan particles and uses thereof |
WO2004087121A2 (en) * | 2003-03-28 | 2004-10-14 | Azaya Therapeutics, Inc. | Water soluble formulations of digitalis glycosides for treating cell-proliferative and other diseases |
US20050022258A1 (en) * | 2003-04-25 | 2005-01-27 | Zheng Cui | Genetically determined mouse model of resistance to transplantable cancers |
CN101184780B (en) | 2005-05-05 | 2012-10-03 | 森馨香料公司 | Production of beta-glucans and mannans |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3301848A (en) * | 1962-10-30 | 1967-01-31 | Pillsbury Co | Polysaccharides and methods for production thereof |
US3396082A (en) * | 1965-06-09 | 1968-08-06 | Agriculture Usa | Glucan production by fermentation of fleshy fungi |
US3856775A (en) * | 1969-07-14 | 1974-12-24 | Ajinomoto Kk | {62 -(1{43 3)-glucans |
US3754925A (en) * | 1970-03-24 | 1973-08-28 | Takeda Chemical Industries Ltd | New thermo gelable polysaccharide containing foodstuffs |
US3987166A (en) * | 1970-05-13 | 1976-10-19 | Kaken Kagaku Kabushiki Kaisha | Treatment of tumors with glucan compositions in mice and rats |
JPS4837590B1 (en) * | 1970-10-19 | 1973-11-12 |
-
1976
- 1976-11-18 JP JP13914376A patent/JPS5366442A/en active Granted
-
1977
- 1977-11-02 CH CH1333477A patent/CH634855A5/en not_active IP Right Cessation
- 1977-11-03 GB GB45783/77A patent/GB1595596A/en not_active Expired
- 1977-11-16 BE BE6046229A patent/BE860885A/en not_active IP Right Cessation
- 1977-11-16 FR FR7734450A patent/FR2421617A1/en active Granted
- 1977-11-17 DK DK510177A patent/DK510177A/en not_active Application Discontinuation
- 1977-11-17 SE SE7713016A patent/SE432939B/en not_active Application Discontinuation
- 1977-11-17 SU SU772543704A patent/SU1024011A3/en active
- 1977-11-18 DE DE19772751570 patent/DE2751570A1/en not_active Withdrawn
- 1977-11-18 CA CA291,230A patent/CA1100951A/en not_active Expired
- 1977-11-18 NL NL7712764A patent/NL7712764A/en not_active Application Discontinuation
-
1979
- 1979-12-24 FR FR7931574A patent/FR2438056A1/en active Granted
-
1981
- 1981-01-14 US US06/224,890 patent/US4454315A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA1100951A (en) | 1981-05-12 |
FR2421617A1 (en) | 1979-11-02 |
DE2751570A1 (en) | 1978-05-24 |
BE860885A (en) | 1978-05-16 |
FR2438056B1 (en) | 1983-10-21 |
FR2421617B1 (en) | 1983-12-23 |
US4454315A (en) | 1984-06-12 |
SE432939B (en) | 1984-04-30 |
JPS5366442A (en) | 1978-06-13 |
DK510177A (en) | 1978-05-19 |
JPS6152125B2 (en) | 1986-11-12 |
GB1595596A (en) | 1981-08-12 |
SU1024011A3 (en) | 1983-06-15 |
FR2438056A1 (en) | 1980-04-30 |
NL7712764A (en) | 1978-05-22 |
CH634855A5 (en) | 1983-02-28 |
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Legal Events
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NAV | Patent application has lapsed |
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