SE7508191L - INSTALL INSULINE EXTRACTION. - Google Patents

INSTALL INSULINE EXTRACTION.

Info

Publication number
SE7508191L
SE7508191L SE7508191A SE7508191A SE7508191L SE 7508191 L SE7508191 L SE 7508191L SE 7508191 A SE7508191 A SE 7508191A SE 7508191 A SE7508191 A SE 7508191A SE 7508191 L SE7508191 L SE 7508191L
Authority
SE
Sweden
Prior art keywords
extract
fat
degree
insulin
extraction
Prior art date
Application number
SE7508191A
Other languages
Swedish (sv)
Inventor
W H Jensen
G R Cebrian
J A Aguas
Original Assignee
Leo Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Sa Lab filed Critical Leo Sa Lab
Publication of SE7508191L publication Critical patent/SE7508191L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

of the disclosure: A method in the recovery of insulin, particularly a method for the removal of fatty matter from an insulin and fatty matter containing pancreas extract. The extract, which may be the raw extract as separated from the residue of the comminuted pancreas glands after extraction, or an extract from which certain proteins different from insulin have been removed by precipitation by adjustment of the pH of the extract to about 8 and filtration, or any other extract containing insulin and fat, is cooled to a temperature at which all the fat freezes and separates out, whereupon the fat is separated from the extract, e.g. by filtration, under continued cooling. The extract can e.g. be cooled down to -30.degree.C to -35.degree.C. The crystallization of the fat can advantageously be carried out at a pH-value of about 3 under cautious agitation, the cooling time, until the final temperature of e.g. -30.degree.C to -35.degree.C is reached, being at least 2-3 hours.
SE7508191A 1974-07-19 1975-07-17 INSTALL INSULINE EXTRACTION. SE7508191L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3204874A GB1503919A (en) 1974-07-19 1974-07-19 Recovery of insulin

Publications (1)

Publication Number Publication Date
SE7508191L true SE7508191L (en) 1976-01-20

Family

ID=10332352

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7508191A SE7508191L (en) 1974-07-19 1975-07-17 INSTALL INSULINE EXTRACTION.

Country Status (8)

Country Link
CA (1) CA1041902A (en)
DE (1) DE2531804A1 (en)
DK (1) DK142313B (en)
ES (1) ES439569A1 (en)
FR (1) FR2278678A1 (en)
GB (1) GB1503919A (en)
NL (1) NL7508461A (en)
SE (1) SE7508191L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1581824A (en) * 1976-01-16 1980-12-31 Leo Sa Lab Preparation of insulin

Also Published As

Publication number Publication date
GB1503919A (en) 1978-03-15
DE2531804A1 (en) 1976-02-05
CA1041902A (en) 1978-11-07
FR2278678B1 (en) 1977-12-16
ES439569A1 (en) 1977-02-16
DK309175A (en) 1976-01-20
NL7508461A (en) 1976-01-21
FR2278678A1 (en) 1976-02-13
DK142313C (en) 1981-03-09
DK142313B (en) 1980-10-13

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