SE7504719L - Forfarande for framstellning av 1,3-bis(2-kloretyl)-1-nitrosokarbamid - Google Patents

Forfarande for framstellning av 1,3-bis(2-kloretyl)-1-nitrosokarbamid

Info

Publication number
SE7504719L
SE7504719L SE7504719A SE7504719A SE7504719L SE 7504719 L SE7504719 L SE 7504719L SE 7504719 A SE7504719 A SE 7504719A SE 7504719 A SE7504719 A SE 7504719A SE 7504719 L SE7504719 L SE 7504719L
Authority
SE
Sweden
Prior art keywords
compounds
bis
solvents
nitrosourea
chloroethyl
Prior art date
Application number
SE7504719A
Other languages
English (en)
Swedish (sv)
Inventor
W H Yanko
D E Sharp
Original Assignee
Department Of Health Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Department Of Health Education filed Critical Department Of Health Education
Publication of SE7504719L publication Critical patent/SE7504719L/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/66Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
    • C07C275/68N-nitroso ureas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7504719A 1974-11-13 1975-04-23 Forfarande for framstellning av 1,3-bis(2-kloretyl)-1-nitrosokarbamid SE7504719L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/523,334 US4028410A (en) 1974-11-13 1974-11-13 Process of preparing 1,3-bis(2-chloroethyl)-1-nitrosourea

Publications (1)

Publication Number Publication Date
SE7504719L true SE7504719L (sv) 1976-05-14

Family

ID=24084603

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7504719A SE7504719L (sv) 1974-11-13 1975-04-23 Forfarande for framstellning av 1,3-bis(2-kloretyl)-1-nitrosokarbamid

Country Status (8)

Country Link
US (1) US4028410A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5156414A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1082223A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH598204A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2528365A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2291187A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1469381A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE7504719L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56120662A (en) * 1980-02-28 1981-09-22 Kowa Co Novel nitrosourea derivative and its preparation
JPS57116043A (en) * 1981-01-12 1982-07-19 Tetsuo Suami New nitrosourea derivative and its preparation
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
GB9719426D0 (en) * 1997-09-13 1997-11-12 Johnson Matthey Plc Novel process
WO2007085026A2 (en) * 2006-01-20 2007-07-26 The Board Of Regents Of The University Of Texas System Compositions and methods for the direct therapy of tumors
JP6325139B2 (ja) 2016-03-02 2018-05-16 ネルファルマ・エッセ・エッルレ・エッレ カルムスチンの安全で効率的な製造方法
WO2017154019A1 (en) * 2016-03-11 2017-09-14 Msn Laboratories Private Limited An improved process for the preparation of 1,3-bis(2-chloroethyl)-1-nitrosourea
WO2017178910A1 (en) 2016-04-16 2017-10-19 Intas Pharmaceuticals Ltd. Process for preparation of carmustine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3465025A (en) * 1966-11-17 1969-09-02 Allied Chem Process for the preparation of isocyanates

Also Published As

Publication number Publication date
DE2528365A1 (de) 1976-05-20
JPS5156414A (en) 1976-05-18
GB1469381A (en) 1977-04-06
CA1082223A (en) 1980-07-22
AU8007675A (en) 1976-10-14
FR2291187A1 (fr) 1976-06-11
US4028410A (en) 1977-06-07
CH598204A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-04-28
FR2291187B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-04-04

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