SE7410757L - - Google Patents

Info

Publication number
SE7410757L
SE7410757L SE7410757A SE7410757A SE7410757L SE 7410757 L SE7410757 L SE 7410757L SE 7410757 A SE7410757 A SE 7410757A SE 7410757 A SE7410757 A SE 7410757A SE 7410757 L SE7410757 L SE 7410757L
Authority
SE
Sweden
Prior art keywords
derivatives
trienal
trienol
nona
cyclohex
Prior art date
Application number
SE7410757A
Other languages
English (en)
Other versions
SE422788B (sv
Inventor
B A Pawson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE7410757L publication Critical patent/SE7410757L/xx
Publication of SE422788B publication Critical patent/SE422788B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C07C403/16—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms not being part of —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7410757A 1973-08-24 1974-08-23 Forfarande for framstellning av vissa angivna 3,7-dimetyl-9-(trimetylcyklohexenyl)-nona-2,6,8-triensyralagalkylestrar SE422788B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1219673A CH585709A5 (fi) 1973-08-24 1973-08-24
US05/495,367 US3931257A (en) 1973-08-24 1974-08-07 Polyene compounds

Publications (2)

Publication Number Publication Date
SE7410757L true SE7410757L (fi) 1975-02-25
SE422788B SE422788B (sv) 1982-03-29

Family

ID=25709815

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7410757A SE422788B (sv) 1973-08-24 1974-08-23 Forfarande for framstellning av vissa angivna 3,7-dimetyl-9-(trimetylcyklohexenyl)-nona-2,6,8-triensyralagalkylestrar

Country Status (12)

Country Link
US (1) US3931257A (fi)
JP (1) JPS5049243A (fi)
BE (1) BE819116A (fi)
CA (1) CA1030154A (fi)
CH (1) CH585709A5 (fi)
DE (1) DE2440606A1 (fi)
DK (1) DK451874A (fi)
FR (1) FR2241297B1 (fi)
GB (1) GB1442107A (fi)
NL (1) NL7411016A (fi)
SE (1) SE422788B (fi)
ZA (1) ZA744964B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187247A (en) * 1974-09-26 1980-02-05 Hoffmann-La Roche Inc. 9-Substituted phenyl-3,7-dimethyl-nona 2,4,6,8-tetraene compounds
US4054589A (en) * 1974-09-26 1977-10-18 Hoffmann-La Roche Inc. Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraene esters
US4107190A (en) * 1974-09-26 1978-08-15 Hoffmann-La Roche Inc. Novel compounds of 9-phenyl-3,7-dimethyl-2,4,6,8-nonatetraenamide
JPS51125234A (en) * 1974-09-26 1976-11-01 Hoffmann La Roche Preparation of polyene compounds
US4190594A (en) * 1975-11-03 1980-02-26 Johnson & Johnson Retinoic acid derivatives
US4108880A (en) * 1975-11-03 1978-08-22 Johnson & Johnson Esters of retinoic acid
CA1111441A (en) * 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
LU77254A1 (fi) * 1977-05-04 1979-01-18
US4199587A (en) * 1977-08-10 1980-04-22 Eisai Co., Ltd. Method of treating hypertension with polyprenyl alcohol ester
US4533554A (en) * 1979-05-18 1985-08-06 Takeda Chemical Industries, Ltd. Quinone derivatives and use
JPS5640651A (en) * 1979-09-12 1981-04-16 Takeda Chem Ind Ltd Quinone compound and its preparation
US4439614A (en) * 1982-09-22 1984-03-27 Sri International 5,6-Methano-5,6-dihydroretinoids
US4642318A (en) * 1982-11-17 1987-02-10 Klaus Wolff Method for decreasing radiation load in PUVA therapy
US4722939A (en) * 1983-07-29 1988-02-02 Usv Pharmaceutical Corporation Derivatives of alpha-alkyl polyolefinic carboxylic acid useful in the treatment of psoriasis
US4523042A (en) * 1983-07-29 1985-06-11 Usv Pharmaceutical Derivatives of alpha-alkyl polyolefinic carboxylic acid useful in the treatment of psoriasis
US4648996A (en) * 1984-07-27 1987-03-10 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4894480A (en) * 1984-07-27 1990-01-16 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4843096A (en) * 1985-06-26 1989-06-27 Stiefel Laboratories, Inc. Treatment of acne
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
US5070108A (en) * 1990-10-12 1991-12-03 Trustees Of The University Of Pennsylvania Methods of treating osteoporosis, increasing bone mineral content and preventing the occurrence of compression fractures in a mammal
US6150421A (en) * 1995-01-11 2000-11-21 Cornell Research Foundation, Inc. Treatment of estrogen-receptor positive breast cancer and estrogen-receptor negative breast cancer with retinoid with CH2 OH at the side chain terminal position
US5786391A (en) * 1995-01-11 1998-07-28 Cornell Research Foundation, Inc. Regulating gene expression using retinoids with Ch2 OH or related groups at the side chain terminal position

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2529498A (en) * 1946-04-12 1950-11-14 Hoffmann La Roche Process for the manufacture of pentaenes
DE1149353B (de) * 1960-08-03 1963-05-30 Bayer Ag Verfahren zur Herstellung von 6-[2', 6', 6'-Trimethylcyclohexen-(1')-yl]-4-methylhexadien-(3, 5)-in-(1) (íÀC-KohlenwasserstoffíÂ)
US3876673A (en) * 1970-08-05 1975-04-08 Rhone Poulenc Sa Intermediates useful in the synthesis of vitamin a
CA939369A (en) * 1970-10-13 1974-01-01 John A. Findlay Process for preparing hydrocarbon acid esters
FR2122694A5 (fi) * 1971-01-20 1972-09-01 Rhone Poulenc Sa

Also Published As

Publication number Publication date
DK451874A (fi) 1975-04-28
GB1442107A (fi) 1976-07-07
SE422788B (sv) 1982-03-29
NL7411016A (nl) 1975-02-26
CH585709A5 (fi) 1977-03-15
US3931257A (en) 1976-01-06
JPS5049243A (fi) 1975-05-01
FR2241297A1 (fi) 1975-03-21
AU7214674A (en) 1976-02-12
ZA744964B (en) 1975-08-27
BE819116A (fr) 1975-02-24
FR2241297B1 (fi) 1978-11-10
CA1030154A (en) 1978-04-25
DE2440606A1 (de) 1975-03-06

Similar Documents

Publication Publication Date Title
SE7410757L (fi)
CA1032946A (en) Esters of 2,2,6,6-tetramethylpiperidinols and hydroxybenzylmalonic acids
BE783562A (fr) Acides et esters 1,4-dihydro-4-oxo-3-quinoleinecarboxyliques etleur preparation
NL7515129A (nl) Werkwijze voor het bereiden van benzoezuren en derivaten daarvan.
NL182279C (nl) Absorberend voortbrengsel, alsmede samenstel ten gebruike bij het vervaardigen van zo'n voortbrengsel.
EG12339A (en) Benzyl-phenoxyalkanecarboxylic acids and the derivatives and their use as herbicides
NL7604129A (nl) Werkwijze voor de bereiding van hydroxycarbon- zuren en derivaten ervan.
TR17051A (tr) Imidazolidinon-(2)tuervleri,bunlarin imaline mahsus usul ve bunlarin herbisidler olarak kullanilmalari
NL7612200A (nl) Retinezuurderivaat alsmede farmaceutisch preparaat voor de behandeling van acne.
IT1055580B (it) Ossimetelen 2 6 morfo lino 4 3a benzimidazoli loroprocedimento di preparazione e loro applicazione in terapeutica
FR2282903A1 (fr) Esters triacyles en positions 9,3'',4'' de l'antibiotique sf-837 m1 et procede de preparation y associe
BE766765A (fr) Alkylphenols disulfones lineaires convenant comme detergents enl'absence de phosphates
AU471819B2 (en) Process forthe manufacture of phosporus-containing condensation products the products and their use as flameproofing agents
PL198768A1 (pl) Sposob wytwarzania 1,1-dwutlenku kwasu 3,4-dwuhydro-2-metylo-4-keto-2h-1,2-benzotiazynokarboksylowego-3 i jego zastosowanie jako produktu posredniego
TR18049A (tr) Triasetonamin'in imaline mahsus usul
TR18053A (tr) O-etil-s, n-propil-o-/piridaz- (3)-on-6-il/tiono-fiolfosforik asid esterler, bunlarin en hazirlanmasina mahsus usul ve bunlarin en sektisidler ve akarisidler olarak kullanilmalari
CH548363A (fr) Procede de preparation d'acides fluorene-2-acetiques et de leurs derives.
SE7508857L (sv) Forfarande for framstellning av 19,20-bis-norprostansyror.
NL7606060A (nl) Werkwijze voor de bereiding van gesubstitueerde thiofeencarbonzuren en derivaten daarvan.
ATA935574A (de) Ausziehfuhrung fur schubladen u.dgl.
SU494891A1 (ru) Способ хирургической декомпрессии лабиринта в эксперименте
BE770405A (fr) Procede de preparation de 14 beta-hydroxy-deltaexp.16- steroides et de 7 alpha-hydroxy-deltaexp.4-steroides
IT998182B (it) Fosforil 1,2,4 triazoli da impiegare come disinfestanti e procedimento per la loro preparazione
IT1059819B (it) Ossazino,5,6,e,indoli sostituiti,loro procedimento di preparazione e loro applicazione in terapia
AU449474B2 (en) THE USE OF p-AMINO-p-UREIDODIPHENYL SULFONE IN TREATING MAREKS DISEASE

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7410757-4

Effective date: 19940410

Format of ref document f/p: F