SE7408323L - - Google Patents
Info
- Publication number
- SE7408323L SE7408323L SE7408323A SE7408323A SE7408323L SE 7408323 L SE7408323 L SE 7408323L SE 7408323 A SE7408323 A SE 7408323A SE 7408323 A SE7408323 A SE 7408323A SE 7408323 L SE7408323 L SE 7408323L
- Authority
- SE
- Sweden
- Prior art keywords
- carbon atoms
- formula
- denotes
- compounds
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Preparation of novel 2-carbalkoxyamino-5(6)-benzimidazole phenyl ethers of the formula I <IMAGE> in which R1 denotes alkyl having 1 to 4 carbon atoms, phenyl or p-nitrophenyl; R2 and R3, in each case independently of one another, denote hydrogen, hydroxyl, alkoxy having 1 to 4 carbon atoms, halogen, trifluoromethyl, alkyl having 1 to 4 carbon atoms or carbalkoxy having 1 to 4 carbon atoms in the alkoxy radical; R4 denotes hydrogen or chlorine; and X denotes oxygen or sulphur. The compounds of the formula I are useful chemotherapeutics and are suitable for the control of parasitic disorders in humans and animals. They are particularly active against a large number of helminths, their activity being particularly pronounced against gastrointestinal strongylidae. The compounds of the formula I are prepared by reacting appropriately substituted 2-aminobenzimidazoles with carbonic acid esters.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2332487A DE2332487A1 (en) | 1973-06-26 | 1973-06-26 | 2-CARBALCOXY-AMINO-BENZIMIDAZOL-5 (6) PHENYL ETHER, THEIR PRODUCTION AND USE IN AGENTS AGAINST HELMETS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7408323L true SE7408323L (en) | 1974-12-27 |
Family
ID=5885126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7408323A SE7408323L (en) | 1973-06-26 | 1974-06-25 |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5753792B2 (en) |
| AT (1) | AT342044B (en) |
| CH (1) | CH608005A5 (en) |
| DE (1) | DE2332487A1 (en) |
| DK (1) | DK341774A (en) |
| ES (1) | ES427457A1 (en) |
| HU (1) | HU168403B (en) |
| IT (1) | IT1056738B (en) |
| NL (1) | NL7408393A (en) |
| SE (1) | SE7408323L (en) |
| YU (1) | YU37149B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9900752D0 (en) * | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
-
1973
- 1973-06-26 DE DE2332487A patent/DE2332487A1/en active Pending
-
1974
- 1974-06-20 ES ES427457A patent/ES427457A1/en not_active Expired
- 1974-06-21 NL NL7408393A patent/NL7408393A/xx not_active Application Discontinuation
- 1974-06-24 IT IT24357/74A patent/IT1056738B/en active
- 1974-06-25 HU HUHO1684A patent/HU168403B/hu unknown
- 1974-06-25 SE SE7408323A patent/SE7408323L/xx not_active Application Discontinuation
- 1974-06-25 YU YU1782/74A patent/YU37149B/en unknown
- 1974-06-25 AT AT525574A patent/AT342044B/en not_active IP Right Cessation
- 1974-06-25 CH CH871674A patent/CH608005A5/en not_active IP Right Cessation
- 1974-06-25 DK DK341774A patent/DK341774A/da not_active Application Discontinuation
- 1974-06-26 JP JP49073156A patent/JPS5753792B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK341774A (en) | 1975-03-17 |
| IT1056738B (en) | 1982-02-20 |
| YU178274A (en) | 1982-06-18 |
| AT342044B (en) | 1978-03-10 |
| NL7408393A (en) | 1974-12-30 |
| CH608005A5 (en) | 1978-12-15 |
| JPS5753792B2 (en) | 1982-11-15 |
| ATA525574A (en) | 1977-07-15 |
| DE2332487A1 (en) | 1975-01-16 |
| YU37149B (en) | 1984-08-31 |
| ES427457A1 (en) | 1976-07-16 |
| JPS5040566A (en) | 1975-04-14 |
| HU168403B (en) | 1976-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7408323-9 |