SE505335C2 - Device for detecting components in exhaled air - Google Patents
Device for detecting components in exhaled airInfo
- Publication number
- SE505335C2 SE505335C2 SE9501351A SE9501351A SE505335C2 SE 505335 C2 SE505335 C2 SE 505335C2 SE 9501351 A SE9501351 A SE 9501351A SE 9501351 A SE9501351 A SE 9501351A SE 505335 C2 SE505335 C2 SE 505335C2
- Authority
- SE
- Sweden
- Prior art keywords
- plate
- exhaled air
- carbon dioxide
- components
- component
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
- A61B5/0836—Measuring rate of CO2 production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Physiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Emergency Medicine (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
10 15 20 25 30 2 505 335 ning som består av ett rörforrnigt stycke, vilket kan vara styvt eller mjukt som en plastpå- se och genom vilken luften ledes. I den ena änden är röret format till ett munstycke. I motsatta änden är en platta anbringad, varvid plattan antingen kan vara en lufttät platta eller ett poröst membran. Plattan är fäst på så vis att den med lätthet kan isärtagas från det övriga rörstycket. Detta kan ske antingen medels skruv- eller snäppanordning eller genom tejpteknik. Ett torrt absorberande material har anbragts på eller införlivats i plattan. Detta absorberande material är så anpassat att det endast absorberar en bestämd mängd av önskvärd gasformig komponent. En fárgindikator i den absorberande substansen visar när den maximala mängden gasformig komponent har absorberats. I det fall att en lufttät platta används finns vid plattans ytterkant hål som släpper ut luften och därmed möjliggör ett luftflöde genom röret. 10 15 20 25 30 2 505 335 consisting of a tubular piece, which may be rigid or soft as a plastic see and through which the air is conducted. At one end, the tube is shaped into a nozzle. IN the opposite end is a plate applied, the plate being either an airtight plate or a porous membrane. The plate is attached in such a way that it can be easily detached from it the rest of the pipe section. This can be done either by means of a screw or snap device or through tape technology. A dry absorbent material has been applied to or incorporated into the plate. This absorbent material is so adapted that it only absorbs a certain amount of desirable gaseous component. A color indicator in the absorbent substance shows when the maximum amount of gaseous component has been absorbed. In the case of an airtight plate used are holes at the outer edge of the plate that release the air and thus enable one air flow through the pipe.
Patienten blåser utandningsluft genom munstycket och bringar utandningsluften att strömma över eller genom plattan. När plattan är mättad kan den särtagas från röret.The patient blows exhaled air through the mouthpiece and brings the exhaled air to flow over or through the plate. When the plate is saturated, it can be separated from the tube.
Plattan analyseras därefter i lämpligt mätinstrument för att påvisa ifrågavarande kompo- nent.The plate is then analyzed in a suitable measuring instrument to detect the component in question. nent.
I en föredragen utföringsform används föreliggande uppfinning för påvisande av isotopmârkt koldioxid i utandningsluft och i synnerhet för påvisande av radioaktiv koldioxid bildad som omsättningsprodukt av bakterien Helícobacter pylori. För detta ändamål har i eller på plattan anbragts ett koldioxidabsorberande material. En patient som tillförts radioaktivt märkt urea får blåsa genom anordningen enligt uppfinningen. Härvid absorberas koldioxid, inklusive radioaktivt märkt koldioxid, på plattan. Plattan avlägsnas sedan från anordningen och analyseras beträffande radioaktivitet i lämplig mätanordning, för att påvisa bakterien Helícobacter pylori.In a preferred embodiment, the present invention is used to detect isotope-labeled carbon dioxide in exhaled air and in particular for the detection of radioactive carbon dioxide formed as a by-product of the bacterium Helícobacter pylori. For this For this purpose, a carbon dioxide absorbing material has been placed in or on the plate. A patient who radiolabeled urea may be blown through the device according to the invention. Hereby carbon dioxide, including radiolabeled carbon dioxide, is absorbed on the plate. The plate is removed then from the device and analyzed for radioactivity in a suitable measuring device, to detect the bacterium Helícobacter pylori.
Föreliggande uppfinning tillhandahåller således en enkel anordning för användning vid påvisande av komponenter i utandningsluft.The present invention thus provides a simple device for use when detecting components in exhaled air.
KORT BESKRIVNING AV RITNINGSFIGURERNA Figur 1. visar en perspektivvy av en utföringsfonn av uppfinningen.BRIEF DESCRIPTION OF THE DRAWINGS Figure 1. shows a perspective view of an embodiment of the invention.
Figur Za. visar en ytterligare utföringsform av uppfinningen i vy ovanifrån.Figure Za. shows a further embodiment of the invention in top view.
Figur 2b. visar utföringsformen i figur 2a från sidan.Figure 2b. shows the embodiment in Figure 2a from the side.
DETALJERAD BESKRIVNING AV RITNINGSFIGURERNA Anordningen i figur 1 visar främst den utföringsform där ett poröst membran används och luften skall bringas att strömma genom plattan. Anordningen består av ett rörforrnigt stycke 1 försett med ett munstycke 2 i ena änden. I den motsatta änden är en löstagbar absorberande platta 3 anbragt. Om en lufttät platta användsji denna utförings- 10 15 20 25 -| tiifllfli 505 335 3 form skall anordningen vara försedd med hål 4 vid plattans ytterkant för att möjliggöra luftflöde genom anordningen. Dessa hål utesluts när ett poröst membran används.DETAILED DESCRIPTION OF THE DRAWING FIGURES The device in Figure 1 mainly shows the embodiment where a porous membrane used and the air must be caused to flow through the plate. The device consists of one tubular piece 1 provided with a nozzle 2 at one end. At the opposite end is one removable absorbent plate 3 placed. If an airtight plate is used in this embodiment, 10 15 20 25 - | tiifllfli 505 335 3 form, the device should be provided with holes 4 at the outer edge of the plate to enable air fl through the device. These holes are excluded when a porous membrane is used.
Figur 2a och b visar två vyer av en utföringsform av anordningen som är lämplig när en lufttät platta används. Beteckningarna i figuren motsvarar dem i figur 1. Den streckade linjen i figur 2b indikerar att hela den övre delen av anordningen innefattande plattan kan frigöras från den undre delen för att föras in i ett mätnstrument. I fall där ett poröst membran används är anordningen ej försedd med hål 4.Figures 2a and b show two views of a suitable embodiment of the device when an airtight plate is used. The designations in the figure correspond to those in figure 1. The The dashed line in Figure 2b indicates that the entire upper part of the device comprising the plate can be released from the lower part to be inserted into a measuring instrument. In cases where one porous membrane is used, the device is not provided with holes 4.
Anordningen fungerar på så vis att en patient blåser utandningsluft genom munstycket 2. Luften passerar då genom det rörformiga stycket 1 och strömmar genom plattan 3 eller över plattan 3 och ut genom hålen 4. Röret är så utformat att maximal kontakt mellan luftströmmen och den absorberande plattan säkerställs. Efter att maximal mängd av gasformig komponent har absorberats, såsom visas av färgindikatom, lossas plattan från det rörformiga stycket och förs in i ett mätinstrument för att påvisa önskad komponent. Alternativt lossas hela övre delen, innefattande plattan, av anordningen och förs in i mätinstrumentet.The device works in such a way that a patient blows exhaled air through nozzle 2. The air then passes through the tubular piece 1 and flows through plate 3 or over the plate 3 and out through the holes 4. The tube is so designed that maximum contact between the air stream and the absorbent plate is ensured. After that maximum amount of gaseous component has been absorbed, as indicated by the color indicator, is released the plate from the tubular piece and inserted into a measuring instrument to detect the desired component. Alternatively, the entire upper part, including the plate, is detached from the device and inserted into the measuring instrument.
Anordningen kan vara utförd i något lämpligt material, företrädesvis kartong, papp eller plast av olika slag. Exempel på plaster är polyeten, polystyren eller PVC. Det är lämpligt att anordningen kan steriliseras medelst strålning eller värme. Det absorberan- de materialet varierar beroende på den komponent som skall påvisas. Exempel på koldi- oxidabsorberande material utgörs av natriumhydroxid och natronkalk. Färgreaktionen på plattan som signalerar att plattan är mättad kan erhållas genom användning av kommersi- ellt tillgänglig natronkalk med fárgindikator. Del av anordningen under eller över det absorberande materialet bör vara transparent för att fárgreaktionen skall kunna avläsas.The device can be made of any suitable material, preferably cardboard, cardboard or plastic of various kinds. Examples of plastics are polyethylene, polystyrene or PVC. The it is convenient that the device can be sterilized by radiation or heat. The absorbent The material varies depending on the component to be detected. Examples of coal oxide-absorbing material consists of sodium hydroxide and soda-lime. The color reaction on the plate signaling that the plate is saturated can be obtained by using commercial Generally available soda lime with color indicator. Part of the device below or above it the absorbent material should be transparent so that the color reaction can be read.
Märkning av komponent som skall påvisas kan exempelvis ske medelst isotoper. Mätin- strumentet för pâvisande av märkt komponent varierar beroende på märkningen. Radioak- tivt märkt komponent kan exempelvis påvisas med ett Geiger Müller rör. Ur hållbar- hetssynpunkt bör anordningen vara förpackad i lufttät påse i hållbar miljö, exempelvis i kvävgas när ett koldioxidabsorberande material används. Av hygieniska skäl kan anord- ningen lämpligen vara anpassad för engångsbruk. l | Labeling of a component to be detected can be done, for example, by means of isotopes. Measurement the instrument for detecting a labeled component varies depending on the label. Radioac- tively labeled component can be detected, for example, with a Geiger Müller tube. From sustainable From a safety point of view, the device should be packed in an airtight bag in a sustainable environment, for example in nitrogen when a carbon dioxide absorbing material is used. For hygienic reasons, be suitable for single use only. l |
Claims (6)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9501351A SE505335C2 (en) | 1995-04-11 | 1995-04-11 | Device for detecting components in exhaled air |
CA002217883A CA2217883C (en) | 1995-04-11 | 1996-04-11 | A device for detecting components in exhaled air |
CZ19973228A CZ289458B6 (en) | 1995-04-11 | 1996-04-11 | Device for detecting at least one component contained in exhalation air |
PCT/SE1996/000474 WO1996032062A1 (en) | 1995-04-11 | 1996-04-11 | A device for detecting components in exhaled air |
JP8530960A JPH11503527A (en) | 1995-04-11 | 1996-04-11 | Device that detects exhaled breath components |
CN96193244A CN1180997A (en) | 1995-04-11 | 1996-04-11 | Device for detecting components in exhaled air |
HU9802039A HU219755B (en) | 1995-04-11 | 1996-04-11 | A device for detecting components in exhaled air |
RU97118330/14A RU2143844C1 (en) | 1995-04-11 | 1996-04-11 | Device for detection of components of expired air |
AU53523/96A AU693344B2 (en) | 1995-04-11 | 1996-04-11 | A device for detecting components in exhaled air |
EP96910283A EP0959764A1 (en) | 1995-04-11 | 1996-04-11 | A device for detecting components in exhaled air |
KR1019970707095A KR19980703695A (en) | 1995-04-11 | 1996-04-11 | Device for detecting components in exhaled air |
MXPA/A/1997/007786A MXPA97007786A (en) | 1995-04-11 | 1997-10-09 | A device for detecting components in aireexhal |
PL96322738A PL185366B1 (en) | 1995-04-11 | 1997-10-09 | Apparatus for detection of constituents contained in exhaled air |
NO974692A NO974692D0 (en) | 1995-04-11 | 1997-10-10 | Device for detecting components in exhalation air |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9501351A SE505335C2 (en) | 1995-04-11 | 1995-04-11 | Device for detecting components in exhaled air |
Publications (3)
Publication Number | Publication Date |
---|---|
SE9501351D0 SE9501351D0 (en) | 1995-04-11 |
SE9501351L SE9501351L (en) | 1996-10-12 |
SE505335C2 true SE505335C2 (en) | 1997-08-11 |
Family
ID=20397933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9501351A SE505335C2 (en) | 1995-04-11 | 1995-04-11 | Device for detecting components in exhaled air |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0959764A1 (en) |
JP (1) | JPH11503527A (en) |
KR (1) | KR19980703695A (en) |
CN (1) | CN1180997A (en) |
AU (1) | AU693344B2 (en) |
CA (1) | CA2217883C (en) |
CZ (1) | CZ289458B6 (en) |
HU (1) | HU219755B (en) |
NO (1) | NO974692D0 (en) |
PL (1) | PL185366B1 (en) |
RU (1) | RU2143844C1 (en) |
SE (1) | SE505335C2 (en) |
WO (1) | WO1996032062A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9604519D0 (en) * | 1996-12-09 | 1996-12-09 | Noster System Ab | Device for capturing and determining carbon dioxide and methods for its use |
SE510922C2 (en) | 1997-11-20 | 1999-07-12 | Studsvik Instr Ab | Apparatus and method for measuring low-energy sample radiation |
GB2381580A (en) * | 2001-10-30 | 2003-05-07 | Sentec Ltd | Sample collection |
GB2427687B (en) | 2005-06-25 | 2009-12-09 | Sensam Ltd | Breath sampling device |
CN102338757A (en) * | 2010-07-26 | 2012-02-01 | 深圳市中核海得威生物科技有限公司 | Helicobacter pylori 14C detection device and method |
CN104640502B (en) * | 2012-09-20 | 2017-09-12 | 皇家飞利浦有限公司 | Low dead band liquid trap |
KR20160067582A (en) | 2014-12-04 | 2016-06-14 | 동아대학교 산학협력단 | Valve including a tube for flow control |
CN105547969A (en) * | 2015-12-23 | 2016-05-04 | 深圳职业技术学院 | Helicobacter pylori tester |
CN106053387B (en) * | 2016-06-29 | 2019-04-23 | 南京青辰光电科技有限公司 | A kind of exhaled gas detection method and device |
JP6419999B1 (en) * | 2018-02-01 | 2018-11-07 | 靖 高島 | Intake device |
CN110243811B (en) * | 2019-04-30 | 2023-05-16 | 广州超威生物科技有限公司 | Method for evaluating release rate of chlorine dioxide |
CN112345635A (en) * | 2020-10-28 | 2021-02-09 | 上海交通大学 | Stomach illness diagnostic system based on exhaled gas volatile organic compound analysis |
CN114137039B (en) * | 2021-11-25 | 2024-01-09 | 西安交通大学 | Gas storage bag integrated with wireless passive ammonia sensor tag and preparation method thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3233462A1 (en) * | 1982-09-09 | 1984-04-12 | Drägerwerk AG, 2400 Lübeck | MOUTHPIECE FOR A BREATH ALCOHOL MEASURING DEVICE |
SU1720002A1 (en) * | 1989-01-18 | 1992-03-15 | Медико-Инженерный Центр Профилактики Заболеваний Органов Дыхания "Аэрозоль" | Method for examining patients with fat and carbohydrate metabolism disorders and device for controlling the exhaled air |
US4947861A (en) * | 1989-05-01 | 1990-08-14 | Hamilton Lyle H | Noninvasive diagnosis of gastritis and duodenitis |
US5171535A (en) * | 1990-10-12 | 1992-12-15 | Wayne Lamont | Breath alcohol tester |
-
1995
- 1995-04-11 SE SE9501351A patent/SE505335C2/en not_active IP Right Cessation
-
1996
- 1996-04-11 KR KR1019970707095A patent/KR19980703695A/en not_active Application Discontinuation
- 1996-04-11 RU RU97118330/14A patent/RU2143844C1/en not_active IP Right Cessation
- 1996-04-11 JP JP8530960A patent/JPH11503527A/en active Pending
- 1996-04-11 AU AU53523/96A patent/AU693344B2/en not_active Ceased
- 1996-04-11 EP EP96910283A patent/EP0959764A1/en not_active Withdrawn
- 1996-04-11 CA CA002217883A patent/CA2217883C/en not_active Expired - Fee Related
- 1996-04-11 CZ CZ19973228A patent/CZ289458B6/en not_active IP Right Cessation
- 1996-04-11 HU HU9802039A patent/HU219755B/en not_active IP Right Cessation
- 1996-04-11 WO PCT/SE1996/000474 patent/WO1996032062A1/en not_active Application Discontinuation
- 1996-04-11 CN CN96193244A patent/CN1180997A/en active Pending
-
1997
- 1997-10-09 PL PL96322738A patent/PL185366B1/en unknown
- 1997-10-10 NO NO974692A patent/NO974692D0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HU219755B (en) | 2001-07-30 |
HUP9802039A3 (en) | 1999-04-28 |
CN1180997A (en) | 1998-05-06 |
HUP9802039A2 (en) | 1998-12-28 |
CA2217883C (en) | 2001-08-07 |
AU693344B2 (en) | 1998-06-25 |
MX9707786A (en) | 1998-06-28 |
SE9501351D0 (en) | 1995-04-11 |
CZ322897A3 (en) | 1998-03-18 |
EP0959764A1 (en) | 1999-12-01 |
CA2217883A1 (en) | 1996-10-17 |
KR19980703695A (en) | 1998-12-05 |
PL185366B1 (en) | 2003-04-30 |
NO974692L (en) | 1997-10-10 |
NO974692D0 (en) | 1997-10-10 |
AU5352396A (en) | 1996-10-30 |
CZ289458B6 (en) | 2002-01-16 |
WO1996032062A1 (en) | 1996-10-17 |
SE9501351L (en) | 1996-10-12 |
RU2143844C1 (en) | 2000-01-10 |
PL322738A1 (en) | 1998-02-16 |
JPH11503527A (en) | 1999-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |