SE416473B - Forfarande for framstellning av 7-(alfa-hydroxi-alfa-fenyl) acetamido-3-(1-metyl-1h-tetrazol-5-yltiometyl)-3-cefem-4-karbonsyra - Google Patents

Forfarande for framstellning av 7-(alfa-hydroxi-alfa-fenyl) acetamido-3-(1-metyl-1h-tetrazol-5-yltiometyl)-3-cefem-4-karbonsyra

Info

Publication number
SE416473B
SE416473B SE7303601A SE7303601A SE416473B SE 416473 B SE416473 B SE 416473B SE 7303601 A SE7303601 A SE 7303601A SE 7303601 A SE7303601 A SE 7303601A SE 416473 B SE416473 B SE 416473B
Authority
SE
Sweden
Prior art keywords
alfa
yltiomethyl
cefem
tetrazol
acetamido
Prior art date
Application number
SE7303601A
Other languages
English (en)
Swedish (sv)
Inventor
J M Greene
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE416473B publication Critical patent/SE416473B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms
    • C07D317/36Alkylene carbonates; Substituted alkylene carbonates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7303601A 1972-03-21 1973-03-15 Forfarande for framstellning av 7-(alfa-hydroxi-alfa-fenyl) acetamido-3-(1-metyl-1h-tetrazol-5-yltiometyl)-3-cefem-4-karbonsyra SE416473B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00236764A US3840531A (en) 1972-03-21 1972-03-21 Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof

Publications (1)

Publication Number Publication Date
SE416473B true SE416473B (sv) 1981-01-05

Family

ID=22890856

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7303601A SE416473B (sv) 1972-03-21 1973-03-15 Forfarande for framstellning av 7-(alfa-hydroxi-alfa-fenyl) acetamido-3-(1-metyl-1h-tetrazol-5-yltiometyl)-3-cefem-4-karbonsyra

Country Status (28)

Country Link
US (1) US3840531A (US20080094685A1-20080424-C00004.png)
JP (1) JPS5541237B2 (US20080094685A1-20080424-C00004.png)
AR (1) AR193934A1 (US20080094685A1-20080424-C00004.png)
AT (1) AT330347B (US20080094685A1-20080424-C00004.png)
AU (1) AU465689B2 (US20080094685A1-20080424-C00004.png)
BE (1) BE796788A (US20080094685A1-20080424-C00004.png)
BG (1) BG20609A3 (US20080094685A1-20080424-C00004.png)
BR (1) BR7301970D0 (US20080094685A1-20080424-C00004.png)
CA (1) CA994327A (US20080094685A1-20080424-C00004.png)
CH (1) CH557382A (US20080094685A1-20080424-C00004.png)
CS (1) CS182782B2 (US20080094685A1-20080424-C00004.png)
DD (1) DD105240A5 (US20080094685A1-20080424-C00004.png)
DE (1) DE2312997A1 (US20080094685A1-20080424-C00004.png)
DK (1) DK143854C (US20080094685A1-20080424-C00004.png)
ES (1) ES412859A1 (US20080094685A1-20080424-C00004.png)
FR (1) FR2182884B1 (US20080094685A1-20080424-C00004.png)
GB (1) GB1400697A (US20080094685A1-20080424-C00004.png)
HU (1) HU165339B (US20080094685A1-20080424-C00004.png)
IE (1) IE37402B1 (US20080094685A1-20080424-C00004.png)
IL (1) IL41711A (US20080094685A1-20080424-C00004.png)
NL (1) NL7303917A (US20080094685A1-20080424-C00004.png)
PH (1) PH9650A (US20080094685A1-20080424-C00004.png)
PL (1) PL85244B1 (US20080094685A1-20080424-C00004.png)
RO (1) RO62621A (US20080094685A1-20080424-C00004.png)
SE (1) SE416473B (US20080094685A1-20080424-C00004.png)
SU (1) SU632295A3 (US20080094685A1-20080424-C00004.png)
YU (1) YU35601B (US20080094685A1-20080424-C00004.png)
ZA (1) ZA731644B (US20080094685A1-20080424-C00004.png)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
US3933808A (en) * 1974-05-20 1976-01-20 Eli Lilly And Company Cephalosporin esters
US3928334A (en) * 1974-06-06 1975-12-23 Bristol Myers Co Process for the production of cefamandole
US3928337A (en) * 1974-08-07 1975-12-23 Bristol Myers Co Process for the production of cefamandole
US3947415A (en) * 1974-12-23 1976-03-30 Eli Lilly And Company Cefamandole derivatives
US3947414A (en) * 1974-12-23 1976-03-30 Eli Lilly And Company Cefamandole derivatives
US4035361A (en) * 1976-03-17 1977-07-12 Eli Lilly And Company Bis-trimethylsilyl cefamandole and process therefor
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
US4115644A (en) * 1977-09-19 1978-09-19 Eli Lilly And Company Process for preparing pure cefamandole from alkali metal and ammonium salts thereof
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 7−置換又は非置換アミノ−3−置換チオメチルセフエムカルボン酸類の新規製造法
JPS5543043A (en) * 1978-09-22 1980-03-26 Sankyo Co Ltd Preparation of 3-substituted thiomethylcephalosporin derivative
US4351947A (en) * 1980-03-06 1982-09-28 Asahi Chemical Industry Co., Ltd. Tetrazole derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3167549A (en) * 1961-05-18 1965-01-26 Smith Kline French Lab Derivatives of 7-aminocephalosporanic acid

Also Published As

Publication number Publication date
BG20609A3 (bg) 1975-12-05
CA994327A (en) 1976-08-03
IL41711A (en) 1976-03-31
AU465689B2 (en) 1975-10-02
HU165339B (US20080094685A1-20080424-C00004.png) 1974-08-28
PL85244B1 (US20080094685A1-20080424-C00004.png) 1976-04-30
JPS5541237B2 (US20080094685A1-20080424-C00004.png) 1980-10-22
YU71073A (en) 1980-10-31
US3840531A (en) 1974-10-08
FR2182884A1 (US20080094685A1-20080424-C00004.png) 1973-12-14
SU632295A3 (ru) 1978-11-05
CS182782B2 (en) 1978-05-31
FR2182884B1 (US20080094685A1-20080424-C00004.png) 1977-01-28
RO62621A (fr) 1978-05-15
ZA731644B (en) 1974-10-30
DK143854C (da) 1982-04-05
BE796788A (fr) 1973-09-17
JPS495987A (US20080094685A1-20080424-C00004.png) 1974-01-19
GB1400697A (en) 1975-07-23
ATA246073A (de) 1975-09-15
ES412859A1 (es) 1976-06-01
IE37402B1 (en) 1977-07-20
AT330347B (de) 1976-06-25
AU5306073A (en) 1974-09-12
IL41711A0 (en) 1973-05-31
DE2312997A1 (de) 1973-11-15
BR7301970D0 (pt) 1974-08-29
DD105240A5 (US20080094685A1-20080424-C00004.png) 1974-04-12
NL7303917A (US20080094685A1-20080424-C00004.png) 1973-09-25
CH557382A (fr) 1974-12-31
DK143854B (da) 1981-10-19
YU35601B (en) 1981-04-30
PH9650A (en) 1976-01-27
IE37402L (en) 1973-09-21
AR193934A1 (es) 1973-05-31

Similar Documents

Publication Publication Date Title
SE407579B (sv) Forfarande for framstellning av n-fosfonometylglycin
SE400771B (sv) Forfarande for framstellning av 3alfa-hydroxi- och 3alfa-hydroxi-19-norpregnaner
SE7308234L (sv) Forfarande for framstellning av o-substituerade 7beta-amino-3-cefem-3-ol-4-karboxylsyraforeningar
SE413246B (sv) Forfarande for framstellning av kolesteroloxidas
NO140731C (no) Fremgangsmaate for fremstilling av dimetyleter
SE419339B (sv) Forfarande for framstellning av substituerade sulfonylacetamidocefalosporiner
SE428218B (sv) Forfarande for framstellning av 6-aminopenicillansyra
SE416473B (sv) Forfarande for framstellning av 7-(alfa-hydroxi-alfa-fenyl) acetamido-3-(1-metyl-1h-tetrazol-5-yltiometyl)-3-cefem-4-karbonsyra
SE385698B (sv) Forfarande for framstellning av kinolinettiksyraderivat
NO139124C (no) Fremgangsmaate for fremstilling av estere
SE382053B (sv) Forfarande for framstellning av bifenylylalkanoylaminopyridiner
SE414164B (sv) Forfarande for framstellning av fosforsyra
NO137589C (no) Fremgangsmaate for fremstilling av fosforsyre
SE409714B (sv) Forfarande for framstellning av 7-(d-alfa-amino-1,4-cyklohexadien-1-ylacetamido)-desacetoxicefalosporansyra-dihydrat
SE383151B (sv) Forfarande for framstellning av 1-hydroxi-2-pyridoner
SE423092B (sv) Forfarande for framstellning av vissa 13-tiaprostaglandiner
SE7611202L (sv) Forfarande for framstellning av pyrazolodiazepinforeningar
SE428692B (sv) Forfarande for framstellning av 7beta-amino-3-cefem-4-karboxylsyraforeningar
SE399708B (sv) Forfarande for framstellning av tioxanton-2-karboxylsyraderivat
SE416725B (sv) Forfarande for framstellning av p-nitrobensoesyra
SE380272B (sv) Forfarande for framstellning av n-fosfonmetylglycin
SE393111B (sv) Forfarande for framstellning av d-2-halogen-6-metyl-8-substituerad - ergolin
SE418746B (sv) Forfarande for framstellning av 7-aminocefalosporansyra eller 7-aminodesacetoxicefalosporansyra
NO147644C (no) Fremgangsmaate for fremstilling av 6-amino-penicillansyre
RO69492A2 (ro) Procedeu pentru prepararea perclor-metil-mercaptanului