SE416201B - Foerfarande foer framstaellning av 1,4-bensodiazepinderivat - Google Patents

Foerfarande foer framstaellning av 1,4-bensodiazepinderivat

Info

Publication number
SE416201B
SE416201B SE7214032-0A SE1403272A SE416201B SE 416201 B SE416201 B SE 416201B SE 1403272 A SE1403272 A SE 1403272A SE 416201 B SE416201 B SE 416201B
Authority
SE
Sweden
Prior art keywords
procedures
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
SE7214032-0A
Other languages
English (en)
Swedish (sv)
Inventor
R I Fryer
L H Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE416201B publication Critical patent/SE416201B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/32—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing a phthalimide or hydrogenated phthalimide ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7214032-0A 1968-06-03 1972-10-30 Foerfarande foer framstaellning av 1,4-bensodiazepinderivat SE416201B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73381868A 1968-06-03 1968-06-03

Publications (1)

Publication Number Publication Date
SE416201B true SE416201B (sv) 1980-12-08

Family

ID=24949226

Family Applications (2)

Application Number Title Priority Date Filing Date
SE6907816A SE372015B (xx) 1968-06-03 1969-06-03
SE7214032-0A SE416201B (sv) 1968-06-03 1972-10-30 Foerfarande foer framstaellning av 1,4-bensodiazepinderivat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE6907816A SE372015B (xx) 1968-06-03 1969-06-03

Country Status (8)

Country Link
US (1) US3567710A (xx)
JP (1) JPS4910676B1 (xx)
AT (2) AT289129B (xx)
CH (1) CH518291A (xx)
ES (1) ES367956A1 (xx)
NL (1) NL6908398A (xx)
SE (2) SE372015B (xx)
YU (1) YU34684B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1414370A (en) * 1973-08-24 1975-11-19 Grindstedvaerket As Benzodiazepines and their production
US3989681A (en) * 1973-11-28 1976-11-02 Hoffmann-La Roche Inc. 7-Azoxy substituted-1,4-benzodiazepin-2-ones
US7029918B2 (en) 2002-01-25 2006-04-18 Roche Diagnostics Operations, Inc. Water-soluble derivatives of lipophilic drugs
CA2723470C (en) * 2007-05-07 2013-12-03 Hale Biopharma Ventures, Llc Nasal administration of benzodiazepines
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
WO2009121039A2 (en) 2008-03-28 2009-10-01 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
US8895546B2 (en) 2009-03-27 2014-11-25 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions

Also Published As

Publication number Publication date
CH518291A (de) 1972-01-31
ES367956A1 (es) 1971-04-16
NL6908398A (xx) 1969-12-05
YU136969A (en) 1979-07-10
AT288405B (de) 1971-03-10
JPS4910676B1 (xx) 1974-03-12
YU34684B (en) 1979-12-31
US3567710A (en) 1971-03-02
SE372015B (xx) 1974-12-09
AT289129B (de) 1971-04-13

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