CH518291A - Verfahren zur Herstellung von Benzodiazepin-Derivaten - Google Patents

Verfahren zur Herstellung von Benzodiazepin-Derivaten

Info

Publication number
CH518291A
CH518291A CH735369A CH735369A CH518291A CH 518291 A CH518291 A CH 518291A CH 735369 A CH735369 A CH 735369A CH 735369 A CH735369 A CH 735369A CH 518291 A CH518291 A CH 518291A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH735369A
Other languages
English (en)
Inventor
Ian Fryer Rodney
Henryk Sternbach Leo
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH944171A priority Critical patent/CH525222A/de
Publication of CH518291A publication Critical patent/CH518291A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/32Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing a phthalimide or hydrogenated phthalimide ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH735369A 1968-06-03 1969-05-14 Verfahren zur Herstellung von Benzodiazepin-Derivaten CH518291A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH944171A CH525222A (de) 1968-06-03 1969-05-14 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73381868A 1968-06-03 1968-06-03

Publications (1)

Publication Number Publication Date
CH518291A true CH518291A (de) 1972-01-31

Family

ID=24949226

Family Applications (1)

Application Number Title Priority Date Filing Date
CH735369A CH518291A (de) 1968-06-03 1969-05-14 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Country Status (8)

Country Link
US (1) US3567710A (de)
JP (1) JPS4910676B1 (de)
AT (2) AT288405B (de)
CH (1) CH518291A (de)
ES (1) ES367956A1 (de)
NL (1) NL6908398A (de)
SE (2) SE372015B (de)
YU (1) YU34684B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1414370A (en) * 1973-08-24 1975-11-19 Grindstedvaerket As Benzodiazepines and their production
US3989681A (en) * 1973-11-28 1976-11-02 Hoffmann-La Roche Inc. 7-Azoxy substituted-1,4-benzodiazepin-2-ones
US7029918B2 (en) 2002-01-25 2006-04-18 Roche Diagnostics Operations, Inc. Water-soluble derivatives of lipophilic drugs
JP2010526822A (ja) * 2007-05-07 2010-08-05 クエスター ファーマシューティカルズ,インク. ベンゾジアゼピン類の経鼻投与
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
ES2586032T3 (es) 2008-03-28 2016-10-11 Hale Biopharma Ventures, Llc Administración de composiciones de benzodiazepinas
WO2012174158A2 (en) 2011-06-14 2012-12-20 Hale Biopharma Ventures, Llc Administration of benzodiazepine

Also Published As

Publication number Publication date
YU136969A (en) 1979-07-10
SE372015B (de) 1974-12-09
AT288405B (de) 1971-03-10
ES367956A1 (es) 1971-04-16
YU34684B (en) 1979-12-31
US3567710A (en) 1971-03-02
SE416201B (sv) 1980-12-08
JPS4910676B1 (de) 1974-03-12
NL6908398A (de) 1969-12-05
AT289129B (de) 1971-04-13

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Legal Events

Date Code Title Description
PL Patent ceased