SE412908B - PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 2-METOXIBENZAMIDES CONTAINING A PYRROLIDINE OR A PIPERIDE REMINDER - Google Patents

PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 2-METOXIBENZAMIDES CONTAINING A PYRROLIDINE OR A PIPERIDE REMINDER

Info

Publication number
SE412908B
SE412908B SE7514143A SE7514143A SE412908B SE 412908 B SE412908 B SE 412908B SE 7514143 A SE7514143 A SE 7514143A SE 7514143 A SE7514143 A SE 7514143A SE 412908 B SE412908 B SE 412908B
Authority
SE
Sweden
Prior art keywords
metoxibenzamides
piperide
reminder
pyrrolidine
procedure
Prior art date
Application number
SE7514143A
Other languages
Swedish (sv)
Other versions
SE7514143L (en
Inventor
J-P Kaplan
B M Raizon
D C L Obitz
P M J Monoury
H Najer
M Jalfre
D P R L Giudicelli
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7441718A external-priority patent/FR2294698A1/en
Priority claimed from FR7531334A external-priority patent/FR2327771A2/en
Priority claimed from FR7534570A external-priority patent/FR2331345A2/en
Application filed by Synthelabo filed Critical Synthelabo
Publication of SE7514143L publication Critical patent/SE7514143L/en
Publication of SE412908B publication Critical patent/SE412908B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
SE7514143A 1974-12-18 1975-12-15 PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 2-METOXIBENZAMIDES CONTAINING A PYRROLIDINE OR A PIPERIDE REMINDER SE412908B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7441718A FR2294698A1 (en) 1974-12-18 1974-12-18 NEW DERIVATIVES OF 2-METHOXY BENZAMIDES SUBSTITUTE, THEIR SALTS, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
FR7531334A FR2327771A2 (en) 1975-10-14 1975-10-14 N-Heterocyclylmethy 12-methoxy-benzamides - useful for treating nervous and psychosomatic disorders (BE170676)
FR7534570A FR2331345A2 (en) 1975-11-13 1975-11-13 N-Heterocyclylmethy 12-methoxy-benzamides - useful for treating nervous and psychosomatic disorders (BE170676)

Publications (2)

Publication Number Publication Date
SE7514143L SE7514143L (en) 1976-06-21
SE412908B true SE412908B (en) 1980-03-24

Family

ID=27250393

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7514143A SE412908B (en) 1974-12-18 1975-12-15 PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 2-METOXIBENZAMIDES CONTAINING A PYRROLIDINE OR A PIPERIDE REMINDER

Country Status (17)

Country Link
AT (1) AT353782B (en)
AU (1) AU497616B2 (en)
CA (1) CA1039731A (en)
CH (1) CH612668A5 (en)
DE (1) DE2556457C3 (en)
DK (1) DK574075A (en)
ES (2) ES443563A1 (en)
FI (1) FI753586A (en)
GB (1) GB1508880A (en)
GR (1) GR59205B (en)
IE (1) IE42210B1 (en)
IL (1) IL48678A (en)
LU (1) LU74026A1 (en)
MX (1) MX3180E (en)
NL (1) NL168219C (en)
NO (1) NO143625C (en)
SE (1) SE412908B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189495A (en) * 1974-09-17 1980-02-19 Synthelabo 2-Methoxy-benzamide derivatives
US4097481A (en) * 1976-11-08 1978-06-27 Riker Laboratories, Inc. Tertiary amide derivatives of pyrrolidine and piperidine
FR2415099A1 (en) * 1978-01-20 1979-08-17 Ile De France NEW DERIVATIVES OF 4-AMINO-5-ALKYLSULFONYL ORTHO-ANISAMIDES, THEIR METHODS OF PREPARATION AND THEIR APPLICATION AS PSYCHOTROPES
FR2440946A2 (en) * 1978-01-20 1980-06-06 Ile De France NOVEL SUBSTITUTED HETEROCYCLIC BENZAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION AS BEHAVIOR MODIFIERS
SE411118B (en) * 1978-03-23 1979-12-03 Astra Laekemedel Ab A PROCEDURE FOR THE PREPARATION OF 2,6-DIALCOXIBENSAMIDES WITH THERAPENTIC PROPERTIES
SE8101536L (en) * 1981-03-11 1982-09-12 Astra Laekemedel Ab Benzamide derivative
SE8205135D0 (en) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-DERIVATIVES
IL109422A0 (en) * 1993-04-30 1994-07-31 Shell Int Research N-benzyl heterocyclic compounds, process for their preparation and pesticidal compositions containing them
EP0623601A1 (en) * 1993-04-30 1994-11-09 Shell Internationale Researchmaatschappij B.V. N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides
WO2000033788A2 (en) * 1998-12-11 2000-06-15 American Biogenetic Sciences Inc. Substituted nitrogen heterocyclic compounds and therapeutic uses thereof

Also Published As

Publication number Publication date
NO754284L (en) 1976-06-21
IE42210B1 (en) 1980-06-18
ES443563A1 (en) 1977-08-16
DE2556457C3 (en) 1981-02-12
DK574075A (en) 1976-06-19
AU497616B2 (en) 1978-12-21
NL168219C (en) 1982-03-16
DE2556457A1 (en) 1976-06-24
IE42210L (en) 1976-06-18
GR59205B (en) 1977-11-26
AT353782B (en) 1979-12-10
AU8764675A (en) 1977-06-23
NO143625B (en) 1980-12-08
SE7514143L (en) 1976-06-21
IL48678A0 (en) 1976-02-29
ES457872A1 (en) 1978-03-01
GB1508880A (en) 1978-04-26
MX3180E (en) 1980-06-11
CA1039731A (en) 1978-10-03
ATA959075A (en) 1979-05-15
CH612668A5 (en) 1979-08-15
IL48678A (en) 1979-01-31
NL7514620A (en) 1976-06-22
NL168219B (en) 1981-10-16
LU74026A1 (en) 1976-11-11
DE2556457B2 (en) 1980-05-29
FI753586A (en) 1976-06-19
NO143625C (en) 1981-03-18

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