SE410185B - Forfarande for framstellning av seko - prostaglandiner med vasodilaterande och blodplettaggregationshemmande effekt - Google Patents

Forfarande for framstellning av seko - prostaglandiner med vasodilaterande och blodplettaggregationshemmande effekt

Info

Publication number
SE410185B
SE410185B SE7404695A SE7404695A SE410185B SE 410185 B SE410185 B SE 410185B SE 7404695 A SE7404695 A SE 7404695A SE 7404695 A SE7404695 A SE 7404695A SE 410185 B SE410185 B SE 410185B
Authority
SE
Sweden
Prior art keywords
plateth
aggregative
vasodilating
seco
prostaglandins
Prior art date
Application number
SE7404695A
Other languages
English (en)
Swedish (sv)
Inventor
Jr E J Cragoe
J H Jones
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE410185B publication Critical patent/SE410185B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/19Acids containing three or more carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
SE7404695A 1973-04-25 1974-04-08 Forfarande for framstellning av seko - prostaglandiner med vasodilaterande och blodplettaggregationshemmande effekt SE410185B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35427373A 1973-04-25 1973-04-25
US41834173A 1973-11-23 1973-11-23

Publications (1)

Publication Number Publication Date
SE410185B true SE410185B (sv) 1979-10-01

Family

ID=26998324

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7404695A SE410185B (sv) 1973-04-25 1974-04-08 Forfarande for framstellning av seko - prostaglandiner med vasodilaterande och blodplettaggregationshemmande effekt

Country Status (14)

Country Link
JP (1) JPS5013331A (es)
AR (1) AR211319A1 (es)
BE (1) BE814089A (es)
CA (1) CA1044701A (es)
CH (1) CH605714A5 (es)
DE (1) DE2419860A1 (es)
ES (1) ES425591A1 (es)
FR (1) FR2226995B1 (es)
GB (1) GB1429092A (es)
IE (1) IE39227B1 (es)
IL (1) IL44636A (es)
NL (1) NL7404839A (es)
NO (1) NO139438C (es)
SE (1) SE410185B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991087A (en) 1973-12-13 1976-11-09 Merck & Co., Inc. 8-Halo-11,12-secoprostaglandins
AT351182B (de) * 1974-06-25 1979-07-10 Merck & Co Inc Verfahren zur herstellung von neuen 9-thia-, 9-oxothia- und 9-dioxothia- 11,12-secoprosta- glandinen
US4018802A (en) * 1975-04-09 1977-04-19 Merck & Co., Inc. 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins and processes
US4128564A (en) * 1976-03-22 1978-12-05 Merck & Co., Inc. 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins

Also Published As

Publication number Publication date
IE39227L (en) 1974-10-25
IL44636A (en) 1977-06-30
BE814089A (fr) 1974-10-24
CA1044701A (en) 1978-12-19
NO741309L (no) 1974-10-28
NL7404839A (es) 1974-10-29
FR2226995B1 (es) 1977-01-28
NO139438C (no) 1979-03-14
IE39227B1 (en) 1978-08-30
AU6797374A (en) 1975-10-23
FR2226995A1 (es) 1974-11-22
DE2419860A1 (de) 1974-11-07
JPS5013331A (es) 1975-02-12
NO139438B (no) 1978-12-04
ES425591A1 (es) 1976-11-01
CH605714A5 (es) 1978-10-13
GB1429092A (en) 1976-03-24
AR211319A1 (es) 1977-11-20
IL44636A0 (en) 1974-06-30

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