SE396756B - Forfarande for framstellning av 6 alfa, 9 alfa-difluor-11 beta, 17, 21-trihydroxi-16 beta-metyl-pregna-1,4-dien, 3, 20-dion-17,21-diacetat - Google Patents

Forfarande for framstellning av 6 alfa, 9 alfa-difluor-11 beta, 17, 21-trihydroxi-16 beta-metyl-pregna-1,4-dien, 3, 20-dion-17,21-diacetat

Info

Publication number
SE396756B
SE396756B SE7303287A SE7303287A SE396756B SE 396756 B SE396756 B SE 396756B SE 7303287 A SE7303287 A SE 7303287A SE 7303287 A SE7303287 A SE 7303287A SE 396756 B SE396756 B SE 396756B
Authority
SE
Sweden
Prior art keywords
alfa
beta
difluor
pregna
dion
Prior art date
Application number
SE7303287A
Other languages
English (en)
Swedish (sv)
Inventor
D E Ayer
A Schlagel
G L Flynn
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE396756B publication Critical patent/SE396756B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7303287A 1972-03-09 1973-03-08 Forfarande for framstellning av 6 alfa, 9 alfa-difluor-11 beta, 17, 21-trihydroxi-16 beta-metyl-pregna-1,4-dien, 3, 20-dion-17,21-diacetat SE396756B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23333772A 1972-03-09 1972-03-09
US31697372A 1972-12-20 1972-12-20

Publications (1)

Publication Number Publication Date
SE396756B true SE396756B (sv) 1977-10-03

Family

ID=26926821

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7303287A SE396756B (sv) 1972-03-09 1973-03-08 Forfarande for framstellning av 6 alfa, 9 alfa-difluor-11 beta, 17, 21-trihydroxi-16 beta-metyl-pregna-1,4-dien, 3, 20-dion-17,21-diacetat

Country Status (13)

Country Link
JP (3) JPS5331156B2 (US20040232935A1-20041125-M00001.png)
AR (1) AR197216A1 (US20040232935A1-20041125-M00001.png)
AU (1) AU468257B2 (US20040232935A1-20041125-M00001.png)
CH (3) CH580116A5 (US20040232935A1-20041125-M00001.png)
DE (1) DE2365992C3 (US20040232935A1-20041125-M00001.png)
DK (1) DK133382B (US20040232935A1-20041125-M00001.png)
ES (1) ES412235A1 (US20040232935A1-20041125-M00001.png)
FR (1) FR2181802B1 (US20040232935A1-20041125-M00001.png)
GB (1) GB1403962A (US20040232935A1-20041125-M00001.png)
HK (1) HK62680A (US20040232935A1-20041125-M00001.png)
NL (1) NL165178C (US20040232935A1-20041125-M00001.png)
PH (1) PH14703A (US20040232935A1-20041125-M00001.png)
SE (1) SE396756B (US20040232935A1-20041125-M00001.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1430223A (en) * 1973-10-25 1976-03-31 Upjohn Co Anti-inflammatory composition comprising steroids
ZA77943B (en) * 1976-03-19 1977-12-28 Upjohn Co Topical steroid clindamycin preparations
NL187577C (nl) * 1978-04-05 1991-11-18 Sibla Srl 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
EP0029924B1 (en) 1979-11-16 1984-08-15 STEROSYNT Ltd. 6-alpha-fluoro-16-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
JPH0240957Y2 (US20040232935A1-20041125-M00001.png) * 1986-08-30 1990-10-31

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB933859A (US20040232935A1-20041125-M00001.png) * 1958-09-06 1963-08-14 Syntex S.A.

Also Published As

Publication number Publication date
PH14703A (en) 1981-11-10
HK62680A (en) 1980-11-14
DE2365992C3 (de) 1982-05-19
NL165178B (nl) 1980-10-15
NL165178C (nl) 1981-03-16
FR2181802B1 (US20040232935A1-20041125-M00001.png) 1976-10-22
NL7303262A (US20040232935A1-20041125-M00001.png) 1973-09-11
DK133382C (US20040232935A1-20041125-M00001.png) 1976-10-04
JPS5344465B2 (US20040232935A1-20041125-M00001.png) 1978-11-29
JPS5344464B2 (US20040232935A1-20041125-M00001.png) 1978-11-29
CH580117A5 (US20040232935A1-20041125-M00001.png) 1976-09-30
JPS5227760A (en) 1977-03-02
JPS4899157A (US20040232935A1-20041125-M00001.png) 1973-12-15
GB1403962A (en) 1975-08-28
AU468257B2 (en) 1976-01-08
DE2365992B2 (de) 1981-08-06
CH580118A5 (US20040232935A1-20041125-M00001.png) 1976-09-30
AU5257973A (en) 1974-08-29
ES412235A1 (es) 1976-01-01
FR2181802A1 (US20040232935A1-20041125-M00001.png) 1973-12-07
JPS5227761A (en) 1977-03-02
DK133382B (da) 1976-05-10
AR197216A1 (es) 1974-03-22
DE2365992A1 (de) 1977-05-18
JPS5331156B2 (US20040232935A1-20041125-M00001.png) 1978-08-31
CH580116A5 (US20040232935A1-20041125-M00001.png) 1976-09-30

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