SE390171B - Sett att framstella 7-(d-alfa-amino-alfa-fenylacetamido)-3-(s-(5-hydroaximetyl-1,3,4-oxadiazol-2-yl)tiometyl)-3-cefem-4-karbonsyra och icke toxiska, farmaceutiskt acceptabla salter derav - Google Patents

Sett att framstella 7-(d-alfa-amino-alfa-fenylacetamido)-3-(s-(5-hydroaximetyl-1,3,4-oxadiazol-2-yl)tiometyl)-3-cefem-4-karbonsyra och icke toxiska, farmaceutiskt acceptabla salter derav

Info

Publication number
SE390171B
SE390171B SE7205524A SE552472A SE390171B SE 390171 B SE390171 B SE 390171B SE 7205524 A SE7205524 A SE 7205524A SE 552472 A SE552472 A SE 552472A SE 390171 B SE390171 B SE 390171B
Authority
SE
Sweden
Prior art keywords
alfa
hydroaximethyl
carcarbic
cefem
phenylacetamido
Prior art date
Application number
SE7205524A
Other languages
English (en)
Swedish (sv)
Inventor
Jr L B Crast
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE390171B publication Critical patent/SE390171B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE7205524A 1971-05-07 1972-04-26 Sett att framstella 7-(d-alfa-amino-alfa-fenylacetamido)-3-(s-(5-hydroaximetyl-1,3,4-oxadiazol-2-yl)tiometyl)-3-cefem-4-karbonsyra och icke toxiska, farmaceutiskt acceptabla salter derav SE390171B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14141771A 1971-05-07 1971-05-07

Publications (1)

Publication Number Publication Date
SE390171B true SE390171B (sv) 1976-12-06

Family

ID=22495600

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7205524A SE390171B (sv) 1971-05-07 1972-04-26 Sett att framstella 7-(d-alfa-amino-alfa-fenylacetamido)-3-(s-(5-hydroaximetyl-1,3,4-oxadiazol-2-yl)tiometyl)-3-cefem-4-karbonsyra och icke toxiska, farmaceutiskt acceptabla salter derav

Country Status (10)

Country Link
US (1) US3757014A (fr)
JP (1) JPS5114489B1 (fr)
CA (1) CA988511A (fr)
DE (1) DE2222434C2 (fr)
DK (1) DK138458B (fr)
FR (1) FR2137586B1 (fr)
GB (1) GB1392536A (fr)
HU (1) HU163486B (fr)
NL (1) NL7205644A (fr)
SE (1) SE390171B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3891634A (en) * 1970-12-17 1975-06-24 Smithkline Corp P-Hydroxymethylphenylacetamidocephalosporins
US3987041A (en) * 1970-12-17 1976-10-19 Smithkline Corporation P-hydroxymethylphenylacetamidocephalosporins
GB1439419A (en) * 1973-01-31 1976-06-16 Bristol Myers Co 3-thiolated-7-acylamido-cephalosporanic acid derivatives
AR207752A1 (es) * 1973-03-30 1976-10-29 Fujisawa Pharmaceutical Co Procedimiento para obtener acidos 7-amino-sustituido-3-tiometilsustituido-3-cefem-4-carboxilicos
US4205166A (en) * 1974-02-20 1980-05-27 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
US4020060A (en) * 1975-07-22 1977-04-26 Richardson-Merrell Inc. 7-[α-Amino-ω-(3,4-methylenedioxyphenyl)acylamido]cephalosporanic acid derivatives
US4033956A (en) * 1975-07-22 1977-07-05 Richardson-Merrell Inc. 7[α-Amino-ω-(2,3-methylenedioxy-phenyl)acylamido]cephalosporanic acid derivatives
US6728315B2 (en) * 2002-07-24 2004-04-27 Apple Computer, Inc. Method and apparatus for variable accuracy inter-picture timing specification for digital video encoding with reduced requirements for division operations
ITMI20022724A1 (it) 2002-12-20 2004-06-21 Antibioticos Spa Sali cristallini del cefdinir.
CN109535144A (zh) * 2019-01-08 2019-03-29 贵州大学 一类1,3,4-噁二唑硫醚类化合物及其制备方法和应用
CN110590878B (zh) * 2019-09-26 2023-03-31 中国科学院海洋研究所 6-噁/噻二唑壳寡糖衍生物及其制备和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
CA988511A (en) 1976-05-04
FR2137586B1 (fr) 1976-04-16
DE2222434A1 (de) 1972-11-23
HU163486B (fr) 1973-09-27
DK138458B (da) 1978-09-11
FR2137586A1 (fr) 1972-12-29
NL7205644A (fr) 1972-11-09
JPS5114489B1 (fr) 1976-05-10
GB1392536A (en) 1975-04-30
DE2222434C2 (de) 1982-11-04
DK138458C (fr) 1979-02-12
US3757014A (en) 1973-09-04

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