SE372009B - - Google Patents

Info

Publication number
SE372009B
SE372009B SE6911318*3A SE1131869A SE372009B SE 372009 B SE372009 B SE 372009B SE 1131869 A SE1131869 A SE 1131869A SE 372009 B SE372009 B SE 372009B
Authority
SE
Sweden
Application number
SE6911318*3A
Inventor
M Thominet
C Laville
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of SE372009B publication Critical patent/SE372009B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE6911318*3A 1961-07-25 1962-07-24 SE372009B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR869010A FR1313758A (fr) 1961-07-25 1961-07-25 Nouveaux benzamides substitués et leur procédé de préparation

Publications (1)

Publication Number Publication Date
SE372009B true SE372009B (es) 1974-12-09

Family

ID=8760052

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8200/62A SE313555B (es) 1961-07-25 1962-07-24
SE6911318*3A SE372009B (es) 1961-07-25 1962-07-24

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE8200/62A SE313555B (es) 1961-07-25 1962-07-24

Country Status (11)

Country Link
US (2) US3177252A (es)
JP (2) JPS5145651B1 (es)
BR (1) BR6240890D0 (es)
CH (1) CH425763A (es)
DK (1) DK106557C (es)
ES (1) ES278660A1 (es)
FI (1) FI42075B (es)
FR (1) FR1313758A (es)
NL (1) NL281394A (es)
OA (1) OA01153A (es)
SE (2) SE313555B (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL281394A (es) * 1961-07-25
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
GB1019781A (es) * 1963-03-05
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
US3885033A (en) * 1967-04-03 1975-05-20 Ile De France Method of anesthetizing a mammal by administration of a substituted 2-arylalkyloxy benzamide
US3509166A (en) * 1968-01-15 1970-04-28 American Cyanamid Co Tetrahydro-pyridine derivatives of benzamide
JPS4940459B1 (es) * 1970-12-21 1974-11-02
GB1399632A (en) * 1972-07-13 1975-07-02 Leo Pharm Prod Ltd Sulphamoyl-benzoic acids
CA1082181A (en) * 1976-06-03 1980-07-22 Eric A. Watts Benzamide derivatives
US4255580A (en) * 1976-08-04 1981-03-10 Siociete D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene bis (oxy) benzamides and derivatives
US4140769A (en) 1976-12-23 1979-02-20 Miles Laboratories, Inc. 3-Substituted salicylamides
US4109005A (en) * 1977-05-11 1978-08-22 A. H. Robins Company, Inc. Method of increasing rate of gastric emptying with pyrrolidinylbenzamides
JPS54130599A (en) * 1978-03-31 1979-10-09 Taisho Pharmaceut Co Ltd Furoindole derivative
JPS54148743A (en) * 1978-05-12 1979-11-21 Asahi Chem Ind Co Ltd Production of methoclopramide
JPS6058224B2 (ja) * 1978-07-31 1985-12-19 旭化成株式会社 メトクロプラミドの製造方法
FR2446274A1 (fr) * 1979-01-15 1980-08-08 Delalande Sa Nouveaux derives de salicylamide, leur procede de preparation et leur application en therapeutique
US4301159A (en) * 1980-06-20 1981-11-17 Shionogi & Co., Ltd. N-(Diethylaminoethyl)-2-alkoxy-benzamide derivatives
US4440941A (en) * 1980-12-22 1984-04-03 Usv Pharmaceutical Corporation Aroyl-aminoacids, amides and esters thereof
US4536386B1 (en) * 1981-01-26 1995-03-07 Robins Co Inc A H Method of controlling emesis caused by cisplatin in cancer chemotherapy
US4666911A (en) * 1981-07-14 1987-05-19 Taiho Pharmaceutical Company Limited Allophanoylpiperazine compound and analgesic composition containing same as active ingredient
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
US5011992A (en) * 1984-06-28 1991-04-30 Bristol-Myers Squibb Company Pharmacologically active substituted benzamides
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
GB8708833D0 (en) * 1987-04-13 1987-05-20 Lilly S A E Organic compounds
IT1216120B (it) * 1988-03-17 1990-02-22 Poli Ind Chimica Spa Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono.
GB8823042D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823041D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823040D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
FR2640139A1 (fr) * 1988-12-14 1990-06-15 Delagrange Laboratoires Application de benzamides substitues comme gastromoteurs
IT1266992B1 (it) * 1993-04-16 1997-01-24 Alfa Wassermann Spa Composti eterociclici, a struttura correlabile alle banzammidi, attivi nelle patologie gastro-intestinali, ad attivita' procinetica ed
US20050137265A1 (en) * 2003-03-31 2005-06-23 Haley Eugene T. Rapidly dissolving metoclopramide solid oral dosage and method thereof
US20040192781A1 (en) * 2003-03-31 2004-09-30 Haley Eugene T. Method of administration for metoclopramide and pharmaceutical formulation therefor
EP1768674A1 (en) 2004-07-16 2007-04-04 ProteoSys AG Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
EP2446903B1 (en) 2006-11-20 2019-10-09 President and Fellows of Harvard College Compositions for treating itch
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment
CA2767646C (en) 2009-07-10 2019-01-29 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
PL2747561T3 (pl) 2011-08-25 2018-11-30 Evoke Pharma, Inc. Leczenie objawów związanych z gastroparezą u osobników płci żeńskiej
JP6265998B2 (ja) 2012-09-17 2018-01-24 ネクター セラピューティクス オリゴマー含有ベンズアミド系化合物
CA2994545A1 (en) 2015-08-03 2017-02-09 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
EP3837008A2 (en) 2018-08-15 2021-06-23 Pharmacyl AB Substituted benzamides and their use in therapy
KR20210045414A (ko) 2018-08-15 2021-04-26 파마실 아베 병리학적 염증에 대한 새로운 의학적 치료
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
BR112021017809A2 (pt) 2019-03-11 2021-11-23 Nocion Therapeutics Inc Bloqueadores de canais iônicos substituídos por éster e métodos para uso
WO2020185830A1 (en) 2019-03-11 2020-09-17 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113811305A (zh) 2019-03-11 2021-12-17 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7513713B2 (ja) 2019-11-06 2024-07-09 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
BR112022008575A2 (pt) 2019-11-06 2022-08-09 Nocion Therapeutics Inc Bloqueadores de canal iônico carregado e métodos para uso
US11717500B2 (en) 2020-02-03 2023-08-08 Pharmacyl Ab Treatment of spondyloarthritis
AU2021236130A1 (en) 2020-03-11 2022-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620543A (es) *
US2460139A (en) * 1945-07-21 1949-01-25 Wallace & Tiernan Inc Alkamine esters of 2-chloro-4-amino benzoic acid
US2691025A (en) * 1951-03-30 1954-10-05 Sterling Drug Inc N-(tertiary-aminoalkyl)-2, 4-disubstituted-benzamides and their preparation
US2810718A (en) * 1953-07-02 1957-10-22 Abbott Lab Basic salicylamides
GB797476A (en) * 1955-09-09 1958-07-02 Bristol Lab Inc Amides of trialkoxybenzoic acids
US2910488A (en) * 1958-01-22 1959-10-27 Merck & Co Inc Aniline derivatives
NL281394A (es) * 1961-07-25

Also Published As

Publication number Publication date
JPS5216104B1 (es) 1977-05-06
JPS5145651B1 (es) 1976-12-04
FI42075B (es) 1970-02-02
NL281394A (es)
BR6240890D0 (pt) 1973-06-14
CH425763A (fr) 1966-12-15
SE313555B (es) 1969-08-18
DK106557C (da) 1967-02-20
FR1313758A (fr) 1963-01-04
ES278660A1 (es) 1962-10-16
OA01153A (fr) 1968-08-07
US3312739A (en) 1967-04-04
US3177252A (en) 1965-04-06

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