SE338311B - - Google Patents

Info

Publication number
SE338311B
SE338311B SE12937/66A SE1293766A SE338311B SE 338311 B SE338311 B SE 338311B SE 12937/66 A SE12937/66 A SE 12937/66A SE 1293766 A SE1293766 A SE 1293766A SE 338311 B SE338311 B SE 338311B
Authority
SE
Sweden
Prior art keywords
halogen
alkyl
alkylamino
reacting
amino
Prior art date
Application number
SE12937/66A
Inventor
S Schuetz
O Behner
F Hoffmeister
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SE338311B publication Critical patent/SE338311B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Novel compounds of the formula <FORM:1104609/C2/1> (wherein A is a bond or a saturated or unsaturated alkylene chain of 1 to 6 carbon atoms; B is amino, alkylamino, dialkylamino, cycloalkylamino, N,N - dicycloalkylamino, N - cycloalkyl - N - alkylamino, N,N - di - (cycloalkylalkyl) amino, N-alkyl-N-arylamino, N-alkyl-N-aralkylamino, piperidino, pyrrolidino, hexamethyleneimino, morpholino, thiomorpholino, N - alkylpiperazino or N - (2 - hydroxyalkyl)-piperazino; n is 1 or 2; X is -CH2-, -(CH2)3- or -CH = CH-; and R1 and R2 are H, halogen, C1- 4 alkyl, alkoxy or alkylthio, OH, NO2, NH2 or CF3) and acid-addition salts thereof, are prepared by reacting the appropriate cyclic ketone or a reactive derivative thereof with (a) the appropriate substituted hydroxylamine- or (b) hydroxylamine and then reacting a metal salt of the product with a halide halogen-CH(3-n)-(A-B)n or with a dihalide halogen-CH2-A-halogen and then the amine HB. The oximes of the invention are stated to be anti-depressants, and they may be made up into pharmaceutical compositions with suitable carriers.
SE12937/66A 1965-11-10 1966-09-26 SE338311B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF47635A DE1247302B (en) 1965-11-10 1965-11-10 Process for the preparation of basic substituted oximes

Publications (1)

Publication Number Publication Date
SE338311B true SE338311B (en) 1971-09-06

Family

ID=7101750

Family Applications (1)

Application Number Title Priority Date Filing Date
SE12937/66A SE338311B (en) 1965-11-10 1966-09-26

Country Status (12)

Country Link
AT (3) AT269838B (en)
BE (1) BE689378A (en)
BR (1) BR6684407D0 (en)
CH (1) CH473781A (en)
DE (1) DE1247302B (en)
DK (1) DK125551B (en)
ES (1) ES333181A1 (en)
FR (2) FR1500629A (en)
GB (1) GB1104609A (en)
IL (1) IL26713A (en)
NL (1) NL154499B (en)
SE (1) SE338311B (en)

Also Published As

Publication number Publication date
FR1500629A (en) 1967-11-03
GB1104609A (en) 1968-02-28
BR6684407D0 (en) 1973-12-26
AT269838B (en) 1969-04-10
AT269839B (en) 1969-04-10
AT269834B (en) 1969-04-10
NL154499B (en) 1977-09-15
BE689378A (en) 1967-05-08
IL26713A (en) 1970-09-17
FR7089M (en) 1969-07-07
ES333181A1 (en) 1967-07-16
DK125551B (en) 1973-03-05
DE1247302B (en) 1967-08-17
NL6615764A (en) 1967-05-11
CH473781A (en) 1969-06-15

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