SE333151B - Foerfarande foer framstaellning av nya centralt haemmande verkande aminosyror och salter daerav - Google Patents

Foerfarande foer framstaellning av nya centralt haemmande verkande aminosyror och salter daerav

Info

Publication number
SE333151B
SE333151B SE8340/64A SE834064A SE333151B SE 333151 B SE333151 B SE 333151B SE 8340/64 A SE8340/64 A SE 8340/64A SE 834064 A SE834064 A SE 834064A SE 333151 B SE333151 B SE 333151B
Authority
SE
Sweden
Prior art keywords
aciding
inhibiting
salts
procedure
preparation
Prior art date
Application number
SE8340/64A
Other languages
English (en)
Inventor
H Keberle
J Faigle
M Wilhelm
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH853763A external-priority patent/CH446376A/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE333151B publication Critical patent/SE333151B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8340/64A 1963-07-09 1964-07-08 Foerfarande foer framstaellning av nya centralt haemmande verkande aminosyror och salter daerav SE333151B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH853763A CH446376A (de) 1963-07-09 1963-07-09 Verfahren zur Herstellung neuer Aminosäuren
CH672964 1964-05-22

Publications (1)

Publication Number Publication Date
SE333151B true SE333151B (sv) 1971-03-08

Family

ID=25700075

Family Applications (4)

Application Number Title Priority Date Filing Date
SE8340/64A SE333151B (sv) 1963-07-09 1964-07-08 Foerfarande foer framstaellning av nya centralt haemmande verkande aminosyror och salter daerav
SE08945/67A SE348462B (sv) 1963-07-09 1964-07-08
SE08944/67A SE348461B (sv) 1963-07-09 1964-07-08
SE08943/67A SE348460B (sv) 1963-07-09 1964-07-08

Family Applications After (3)

Application Number Title Priority Date Filing Date
SE08945/67A SE348462B (sv) 1963-07-09 1964-07-08
SE08944/67A SE348461B (sv) 1963-07-09 1964-07-08
SE08943/67A SE348460B (sv) 1963-07-09 1964-07-08

Country Status (9)

Country Link
US (1) US3471548A (sv)
BE (1) BE650258A (sv)
BR (1) BR6460727D0 (sv)
CH (1) CH449645A (sv)
DE (1) DE1493536B1 (sv)
ES (1) ES301814A1 (sv)
FR (2) FR3677M (sv)
GB (1) GB1017439A (sv)
SE (4) SE333151B (sv)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
US3947579A (en) * 1974-06-03 1976-03-30 Nelson Research & Development Company Method and composition for potentiating neuroleptic drugs
US3978216A (en) * 1974-06-03 1976-08-31 Nelson Research & Development Company Method for treating schizophrenia and method and composition for potentiating neuroleptic drugs
US4084000A (en) * 1975-07-16 1978-04-11 Nelson Research And Development Company Method of treating schizophrenia
US4126684A (en) * 1976-02-11 1978-11-21 Ciba-Geigy Corporation 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
NL7706429A (nl) * 1977-06-10 1978-12-12 Univ Erasmus Werkwijze voor de bereiding van een geneesmid- del met angst en angstequivalenten opheffende werking en gevormd geneesmiddel met een derge- lijke werking.
NL8006135A (nl) * 1980-11-10 1982-06-01 Univ Erasmus Geneesmiddel met angst en angstequivalenten opheffende werking en werkwijze voor de bereiding van een dergelijk geneesmiddel.
US5006560A (en) * 1989-12-20 1991-04-09 Schering Corporation Use of GABA-B selective agonists as anti-tussive agents
CA2240937C (en) * 1995-12-20 2004-06-01 Farmarc Nederland B.V. A process for the optical resolution of 3-(p-chlorophenyl)-glutaramide
WO1998003167A1 (en) 1996-07-24 1998-01-29 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
WO2002043762A2 (en) 2000-11-30 2002-06-06 Pfizer Products Inc. Combination of gaba agonists and sorbitol dehydrogenase inhibitors
MXPA03004871A (es) 2000-11-30 2003-08-19 Pfizer Prod Inc Combinacion de agonistas de gaba e inhibidores de aldosa-reductasa.
CA2525366A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
KR101140559B1 (ko) * 2003-08-20 2012-07-05 제노포트 인코포레이티드 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
EP1737466A1 (en) * 2004-01-29 2007-01-03 Pfizer Products Inc. COMBINATION OF y-AMINOBUTYRIC ACID MODULATORS AND 5-HT-1b RECEPTOR ANTAGONISTS
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
EP2058008B1 (en) 2006-08-11 2013-08-21 National University Corporation Nagoya University Anti-obesity agent and use thereof
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
CN101631768A (zh) * 2007-03-15 2010-01-20 太阳医药高级研究有限公司 新型前药
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
US20180208544A1 (en) 2015-07-13 2018-07-26 Piramal Enterprises Limited An improved process for the preparation of baclofen and its intermediate
CN106187794A (zh) * 2016-07-12 2016-12-07 安徽省逸欣铭医药科技有限公司 一种巴氯芬的绿色工业化生产方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125583A (en) * 1964-03-17 Hjnc oxchaxohxchc o oh

Also Published As

Publication number Publication date
BE650258A (sv) 1965-01-08
GB1017439A (en) 1966-01-19
FR3692M (fr) 1965-11-15
SE348462B (sv) 1972-09-04
CH449645A (de) 1968-01-15
DE1493536B1 (de) 1971-10-14
US3471548A (en) 1969-10-07
BR6460727D0 (pt) 1973-08-02
SE348461B (sv) 1972-09-04
FR3677M (fr) 1965-11-08
ES301814A1 (es) 1965-01-01
SE348460B (sv) 1972-09-04

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