SE311519B - - Google Patents

Info

Publication number
SE311519B
SE311519B SE1352462A SE1352462A SE311519B SE 311519 B SE311519 B SE 311519B SE 1352462 A SE1352462 A SE 1352462A SE 1352462 A SE1352462 A SE 1352462A SE 311519 B SE311519 B SE 311519B
Authority
SE
Sweden
Application number
SE1352462A
Inventor
B Ekstroem
B Sjoeberg
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE1352462A priority Critical patent/SE311519B/xx
Priority to DE19631445434 priority patent/DE1445434A1/de
Priority to FI246763A priority patent/FI42332C/fi
Priority to DK582163A priority patent/DK121231B/da
Priority to NO15123463A priority patent/NO132692C/no
Priority to GB4967663A priority patent/GB1073530A/en
Publication of SE311519B publication Critical patent/SE311519B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SE1352462A 1962-12-14 1962-12-14 SE311519B (no)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE1352462A SE311519B (no) 1962-12-14 1962-12-14
DE19631445434 DE1445434A1 (de) 1962-12-14 1963-11-28 Cephalosporine und Verfahren zu deren Herstellung
FI246763A FI42332C (fi) 1962-12-14 1963-12-13 Tapa valmistaa alfa-amino- tai atsidosubstituoituja 7-fenyyli-asetamido-sefalosporaanihappoja käyttämällä 7-aminosefalosporaanihapon trialkyylisilyylijohdannaisia lähtöaineena
DK582163A DK121231B (da) 1962-12-14 1963-12-13 Fremgangsmåde til fremstilling af derivater af 7-aminocephalosporansyre eller salte deraf.
NO15123463A NO132692C (no) 1962-12-14 1963-12-13
GB4967663A GB1073530A (en) 1962-12-14 1963-12-16 Process for the preparation of cephalosporins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1352462A SE311519B (no) 1962-12-14 1962-12-14

Publications (1)

Publication Number Publication Date
SE311519B true SE311519B (no) 1969-06-16

Family

ID=20297538

Family Applications (1)

Application Number Title Priority Date Filing Date
SE1352462A SE311519B (no) 1962-12-14 1962-12-14

Country Status (6)

Country Link
DE (1) DE1445434A1 (no)
DK (1) DK121231B (no)
FI (1) FI42332C (no)
GB (1) GB1073530A (no)
NO (1) NO132692C (no)
SE (1) SE311519B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA695612B (en) * 1968-08-23 1971-03-31 Lilly Co Eli Preparation of cephalosporin compounds
CS165353B2 (no) * 1969-12-18 1975-12-22
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
IE36041B1 (en) * 1971-01-29 1976-08-04 Glaxo Lab Ltd Improvements in or relating to antibiotics
US4024134A (en) * 1971-01-29 1977-05-17 Glaxo Laboratories Limited Syn isomers of cephalosporins having α-hydroximino- or α-acyloxyiminoacylamido groups at position-7
GB1389194A (en) * 1971-01-29 1975-04-03 Glaxo Lab Ltd Antibiotics
US4209616A (en) * 1971-01-29 1980-06-24 Glaxo Laboratories Limited Syn isomers of cephalosporins having α-hydroximino- or α-acyloxyiminoacylamido groups at position-7
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
BE783448A (fr) * 1971-05-14 1972-11-13 Glaxo Lab Ltd Perfectionnements relatifs aux antibiotiques
BE793595A (fr) * 1972-01-03 1973-07-02 Hoffmann La Roche Derives acyles
GB1472534A (en) * 1973-07-06 1977-05-04 Glaxo Lab Ltd 7beta-hydroxyiminoacylamido-cephalosporins
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
US4316017A (en) 1979-03-19 1982-02-16 Bristol-Myers Company Cephalosporin intermediates
US4223135A (en) 1979-03-19 1980-09-16 Bristol-Myers Company Production of cephalosporins
US4316016A (en) 1979-03-19 1982-02-16 Bristol-Myers Company Cephalosporin intermediates
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
AT402928B (de) * 1994-12-23 1997-09-25 Biochemie Gmbh Neues verfahren zur herstellung von cefotaxim

Also Published As

Publication number Publication date
GB1073530A (en) 1967-06-28
FI42332C (fi) 1970-07-10
NO132692B (no) 1975-09-08
FI42332B (no) 1970-03-31
DE1445434A1 (de) 1969-01-16
DK121231B (da) 1971-09-27
NO132692C (no) 1975-12-17

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