SE311167B - - Google Patents
Info
- Publication number
- SE311167B SE311167B SE13318/63A SE1331863A SE311167B SE 311167 B SE311167 B SE 311167B SE 13318/63 A SE13318/63 A SE 13318/63A SE 1331863 A SE1331863 A SE 1331863A SE 311167 B SE311167 B SE 311167B
- Authority
- SE
- Sweden
- Prior art keywords
- lower alkyl
- hydrogen
- groups
- coo
- chlorine
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- -1 nitro, amino, hydroxy Chemical group 0.000 abstract 5
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 4
- 229910052801 chlorine Inorganic materials 0.000 abstract 4
- 239000000460 chlorine Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000006239 protecting group Chemical group 0.000 abstract 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 230000010933 acylation Effects 0.000 abstract 3
- 238000005917 acylation reaction Methods 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 3
- 229910052794 bromium Inorganic materials 0.000 abstract 3
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- 239000011737 fluorine Substances 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 238000005984 hydrogenation reaction Methods 0.000 abstract 2
- KYSAZZKSGGZBIY-UHFFFAOYSA-N [2-(4-ethoxybenzoyl)-3-hydroxy-1-benzofuran-6-yl] 4-ethoxybenzoate Chemical compound C(C)OC1=CC=C(C(=O)C=2OC3=C(C2O)C=CC(=C3)OC(C3=CC=C(C=C3)OCC)=O)C=C1 KYSAZZKSGGZBIY-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 230000031709 bromination Effects 0.000 abstract 1
- 238000005893 bromination reaction Methods 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001907 coumarones Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- WBQTXTBONIWRGK-UHFFFAOYSA-N sodium;propan-2-olate Chemical compound [Na+].CC(C)[O-] WBQTXTBONIWRGK-UHFFFAOYSA-N 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Safety Valves (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1084290D GB1084290A (enrdf_load_stackoverflow) | 1963-12-02 | ||
| SE13318/63A SE311167B (enrdf_load_stackoverflow) | 1963-12-02 | 1963-12-02 | |
| IL22428A IL22428A (en) | 1963-12-02 | 1964-11-11 | Benzofuran derivatives and process for their production |
| BR164404/64A BR6464404D0 (pt) | 1963-12-02 | 1964-11-17 | Processo para a producao de novos derivados da benzofuran |
| DE19641445465 DE1445465A1 (de) | 1963-12-02 | 1964-11-21 | Verfahren zur Herstellung neuer Benzofuranderivate |
| BE656100A BE656100A (enrdf_load_stackoverflow) | 1963-12-02 | 1964-11-23 | |
| CH1507264A CH451962A (de) | 1963-12-02 | 1964-11-23 | Verfahren zur Herstellung neuer Benzofuranderivate |
| AT997764A AT252227B (de) | 1963-12-02 | 1964-11-25 | Verfahren zur Herstellung von neuen Benzofuranen |
| ES0306577A ES306577A1 (es) | 1963-12-02 | 1964-11-30 | Procedimiento para la obtencion de nuevos compuestos de benzofurano. |
| NO155816A NO117923B (enrdf_load_stackoverflow) | 1963-12-02 | 1964-12-01 | |
| DK591164AA DK109989C (da) | 1963-12-02 | 1964-12-01 | Fremgangsmåde til fremstilling af benzofuranderivater eller salte heraf. |
| NL6413996A NL6413996A (enrdf_load_stackoverflow) | 1963-12-02 | 1964-12-02 | |
| FR997050A FR3884M (enrdf_load_stackoverflow) | 1963-12-02 | 1964-12-02 | |
| FR997051A FR1415355A (fr) | 1963-12-02 | 1964-12-02 | Dérivés du benzofurane et procédé d'obtention |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE13318/63A SE311167B (enrdf_load_stackoverflow) | 1963-12-02 | 1963-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE311167B true SE311167B (enrdf_load_stackoverflow) | 1969-06-02 |
Family
ID=20297200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE13318/63A SE311167B (enrdf_load_stackoverflow) | 1963-12-02 | 1963-12-02 |
Country Status (13)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1209558A (en) * | 1968-07-06 | 1970-10-21 | Delalande Sa | Derivatives of 5-cinnamoyl benzofuran and process for their preparation |
| WO2000046194A1 (fr) * | 1999-02-08 | 2000-08-10 | Shionogi & Co., Ltd. | Derives d'amine cyclique et leurs utilisations |
| FR2862646B1 (fr) * | 2003-11-20 | 2006-02-24 | Merck Sante Sas | Nouveaux composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
-
0
- GB GB1084290D patent/GB1084290A/en not_active Expired
-
1963
- 1963-12-02 SE SE13318/63A patent/SE311167B/xx unknown
-
1964
- 1964-11-11 IL IL22428A patent/IL22428A/xx unknown
- 1964-11-17 BR BR164404/64A patent/BR6464404D0/pt unknown
- 1964-11-21 DE DE19641445465 patent/DE1445465A1/de active Pending
- 1964-11-23 CH CH1507264A patent/CH451962A/de unknown
- 1964-11-23 BE BE656100A patent/BE656100A/xx unknown
- 1964-11-25 AT AT997764A patent/AT252227B/de active
- 1964-11-30 ES ES0306577A patent/ES306577A1/es not_active Expired
- 1964-12-01 NO NO155816A patent/NO117923B/no unknown
- 1964-12-01 DK DK591164AA patent/DK109989C/da active
- 1964-12-02 FR FR997050A patent/FR3884M/fr not_active Expired
- 1964-12-02 NL NL6413996A patent/NL6413996A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT252227B (de) | 1967-02-10 |
| ES306577A1 (es) | 1965-05-01 |
| DK109989C (da) | 1968-08-19 |
| BR6464404D0 (pt) | 1973-08-02 |
| CH451962A (de) | 1968-05-15 |
| IL22428A (en) | 1969-01-29 |
| BE656100A (enrdf_load_stackoverflow) | 1965-03-16 |
| NO117923B (enrdf_load_stackoverflow) | 1969-10-13 |
| NL6413996A (enrdf_load_stackoverflow) | 1965-06-03 |
| DE1445465A1 (de) | 1972-04-20 |
| GB1084290A (enrdf_load_stackoverflow) | 1900-01-01 |
| FR3884M (enrdf_load_stackoverflow) | 1966-01-31 |
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