SE307351B - - Google Patents
Info
- Publication number
- SE307351B SE307351B SE157066A SE157066A SE307351B SE 307351 B SE307351 B SE 307351B SE 157066 A SE157066 A SE 157066A SE 157066 A SE157066 A SE 157066A SE 307351 B SE307351 B SE 307351B
- Authority
- SE
- Sweden
- Prior art keywords
- steroids
- prepared
- chloroethynyl
- bromine
- triphenylphosphine
- Prior art date
Links
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 3
- 229910052794 bromium Inorganic materials 0.000 abstract 3
- 150000003431 steroids Chemical class 0.000 abstract 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- OCXGTPDKNBIOTF-UHFFFAOYSA-N dibromo(triphenyl)-$l^{5}-phosphane Chemical compound C=1C=CC=CC=1P(Br)(C=1C=CC=CC=1)(Br)C1=CC=CC=C1 OCXGTPDKNBIOTF-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 229910052740 iodine Inorganic materials 0.000 abstract 2
- 239000011630 iodine Substances 0.000 abstract 2
- HVLLSGMXQDNUAL-UHFFFAOYSA-N triphenyl phosphite Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)OC1=CC=CC=C1 HVLLSGMXQDNUAL-UHFFFAOYSA-N 0.000 abstract 2
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 abstract 2
- DVSJBCFGNHBBKG-UHFFFAOYSA-N 1,2,2-trichloro-n,n-diethylethenamine Chemical compound CCN(CC)C(Cl)=C(Cl)Cl DVSJBCFGNHBBKG-UHFFFAOYSA-N 0.000 abstract 1
- HZNVUJQVZSTENZ-UHFFFAOYSA-N 2,3-dichloro-5,6-dicyano-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(C#N)=C(C#N)C1=O HZNVUJQVZSTENZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 230000001548 androgenic effect Effects 0.000 abstract 1
- 230000001986 anti-endotoxic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001911 anti-progestational effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- QQVDYSUDFZZPSU-UHFFFAOYSA-M chloromethylidene(dimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)=CCl QQVDYSUDFZZPSU-UHFFFAOYSA-M 0.000 abstract 1
- ASWXNYNXAOQCCD-UHFFFAOYSA-N dichloro(triphenyl)-$l^{5}-phosphane Chemical compound C=1C=CC=CC=1P(Cl)(C=1C=CC=CC=1)(Cl)C1=CC=CC=C1 ASWXNYNXAOQCCD-UHFFFAOYSA-N 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB546965A GB1061241A (en) | 1965-02-08 | 1965-02-08 | 6-halomethyl-3-oxo-4,6-dienic steroids |
| GB2068565 | 1965-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE307351B true SE307351B (en, 2012) | 1969-01-07 |
Family
ID=26239906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE157066A SE307351B (en, 2012) | 1965-02-08 | 1966-02-08 |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE676204A (en, 2012) |
| BR (1) | BR6677011D0 (en, 2012) |
| CH (1) | CH478108A (en, 2012) |
| DE (1) | DE1568076A1 (en, 2012) |
| DK (1) | DK114771B (en, 2012) |
| GB (1) | GB1061241A (en, 2012) |
| IL (1) | IL25048A (en, 2012) |
| NL (2) | NL6601540A (en, 2012) |
| SE (1) | SE307351B (en, 2012) |
-
0
- NL NL128374D patent/NL128374C/xx active
-
1965
- 1965-02-08 GB GB546965A patent/GB1061241A/en not_active Expired
-
1966
- 1966-01-25 IL IL2504866A patent/IL25048A/xx unknown
- 1966-02-07 NL NL6601540A patent/NL6601540A/xx unknown
- 1966-02-07 CH CH166266A patent/CH478108A/de not_active IP Right Cessation
- 1966-02-08 DK DK63966A patent/DK114771B/da unknown
- 1966-02-08 BR BR17701166A patent/BR6677011D0/pt unknown
- 1966-02-08 BE BE676204D patent/BE676204A/xx unknown
- 1966-02-08 DE DE19661568076 patent/DE1568076A1/de active Pending
- 1966-02-08 SE SE157066A patent/SE307351B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6601540A (en, 2012) | 1966-08-09 |
| GB1061241A (en) | 1967-03-08 |
| NL128374C (en, 2012) | |
| BR6677011D0 (pt) | 1973-09-06 |
| DK114771B (da) | 1969-08-04 |
| CH478108A (de) | 1969-09-15 |
| DE1568076A1 (de) | 1970-05-06 |
| IL25048A (en) | 1969-11-30 |
| BE676204A (en, 2012) | 1966-06-16 |
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