SE0403057D0 - Purification of immunoglobulins - Google Patents

Purification of immunoglobulins

Info

Publication number
SE0403057D0
SE0403057D0 SE0403057A SE0403057A SE0403057D0 SE 0403057 D0 SE0403057 D0 SE 0403057D0 SE 0403057 A SE0403057 A SE 0403057A SE 0403057 A SE0403057 A SE 0403057A SE 0403057 D0 SE0403057 D0 SE 0403057D0
Authority
SE
Sweden
Prior art keywords
immunoglobulins
purification
particles
kav
ameter
Prior art date
Application number
SE0403057A
Other languages
Swedish (sv)
Inventor
Hans Berg
Hans Johansson
Gunnar Malmquist
Per-Mikael Aaberg
Original Assignee
Amersham Biosciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Biosciences Ab filed Critical Amersham Biosciences Ab
Priority to SE0403057A priority Critical patent/SE0403057D0/en
Publication of SE0403057D0 publication Critical patent/SE0403057D0/en
Priority to PCT/SE2005/001900 priority patent/WO2006065208A1/en
Priority to AU2005317279A priority patent/AU2005317279C1/en
Priority to JP2007546603A priority patent/JP5787461B2/en
Priority to EP05815565A priority patent/EP1830947A4/en
Priority to CA2586803A priority patent/CA2586803C/en
Priority to CN200580043050A priority patent/CN100574840C/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

The present invention relates to a separation matrix comprised of porous particles to which antibody-binding protein ligands have been immobilised, wherein the ligand density is in the range of 5.0-10 mg/ml; the gel phase distribution coefficient of the particles expressed as Kav for a dextran of size 110 kDa is above 0.65 and the median particle di-ameter is between 65-84 mum. The carbohydrate material is preferably highly cross-linked agarose.
SE0403057A 2004-12-14 2004-12-14 Purification of immunoglobulins SE0403057D0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE0403057A SE0403057D0 (en) 2004-12-14 2004-12-14 Purification of immunoglobulins
PCT/SE2005/001900 WO2006065208A1 (en) 2004-12-14 2005-12-12 Purification of immunoglobulins
AU2005317279A AU2005317279C1 (en) 2004-12-14 2005-12-12 Purification of immunoglobulins
JP2007546603A JP5787461B2 (en) 2004-12-14 2005-12-12 Immunoglobulin purification method
EP05815565A EP1830947A4 (en) 2004-12-14 2005-12-12 Purification of immunoglobulins
CA2586803A CA2586803C (en) 2004-12-14 2005-12-12 Purification of immunoglobulins
CN200580043050A CN100574840C (en) 2004-12-14 2005-12-12 The purifying of immunoglobulin (Ig)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0403057A SE0403057D0 (en) 2004-12-14 2004-12-14 Purification of immunoglobulins

Publications (1)

Publication Number Publication Date
SE0403057D0 true SE0403057D0 (en) 2004-12-14

Family

ID=33563219

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0403057A SE0403057D0 (en) 2004-12-14 2004-12-14 Purification of immunoglobulins

Country Status (2)

Country Link
CN (1) CN100574840C (en)
SE (1) SE0403057D0 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102179237A (en) * 2010-04-26 2011-09-14 无锡加莱克色谱科技有限公司 Affinity chromatographic packing for separating and purifying monoclonal antibody and antibodyglobulin and preparation method thereof
US9624261B2 (en) * 2011-03-29 2017-04-18 Glaxosmithkline Llc Buffer system for protein purification
US10266563B2 (en) * 2014-06-24 2019-04-23 Ge Healthcare Bio-Process R&D Ab Chromatography method
GB201515339D0 (en) * 2015-08-28 2015-10-14 Ge Healthcare Bio Sciences Ab A seperation matrix and a method of seperating antibodies
CN106543274B (en) * 2016-10-18 2020-10-27 天津大学 Derivative of protein A structural domain Z with specific binding effect on antibody and application thereof
GB201703116D0 (en) * 2017-02-27 2017-04-12 Ge Healthcare Bioprocess R&D Ab A seperation matrix and a method of seperating antibodies

Also Published As

Publication number Publication date
CN100574840C (en) 2009-12-30
CN101087637A (en) 2007-12-12

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