SE0303542D0 - 1,2,3,4-Tetrahydroisoquinoline derivaties, preparations thereof and uses thereof - Google Patents
1,2,3,4-Tetrahydroisoquinoline derivaties, preparations thereof and uses thereofInfo
- Publication number
- SE0303542D0 SE0303542D0 SE0303542A SE0303542A SE0303542D0 SE 0303542 D0 SE0303542 D0 SE 0303542D0 SE 0303542 A SE0303542 A SE 0303542A SE 0303542 A SE0303542 A SE 0303542A SE 0303542 D0 SE0303542 D0 SE 0303542D0
- Authority
- SE
- Sweden
- Prior art keywords
- preparations
- tetrahydroisoquinoline derivatives
- compounds
- tetrahydroisoquinoline
- derivatives
- Prior art date
Links
- UWYZHKAOTLEWKK-UHFFFAOYSA-N 1,2,3,4-tetrahydroisoquinoline Chemical class C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P25/32—Alcohol-abuse
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0303542A SE0303542D0 (sv) | 2003-12-22 | 2003-12-22 | 1,2,3,4-Tetrahydroisoquinoline derivaties, preparations thereof and uses thereof |
| PCT/SE2004/001939 WO2005061484A1 (en) | 2003-12-22 | 2004-12-20 | 1,2,3,4-tetrahydroisoquinoline derivatives, preparations thereof and uses thereof |
| CNA200480041965XA CN1918147A (zh) | 2003-12-22 | 2004-12-20 | 1,2,3,4-四氢异喹啉衍生物、其制备及其用途 |
| JP2006546907A JP2007515477A (ja) | 2003-12-22 | 2004-12-20 | 1,2,3,4−テトラヒドロイソキノリン誘導体、それらの製造法および使用 |
| MXPA06007040A MXPA06007040A (es) | 2003-12-22 | 2004-12-20 | Derivados de 1,2,3,4-tetrahidroisoquinolina, preparaciones y usos de los mismos. |
| US10/596,546 US20090023728A1 (en) | 2003-12-22 | 2004-12-20 | 1,2,3,4-Tetrahydroisoquinoline Derivatives, Preparations Thereof and Uses Thereof |
| KR1020067014795A KR20060127903A (ko) | 2003-12-22 | 2004-12-20 | 1,2,3,4-테트라히드로이소퀴놀린 유도체, 그의 제조 방법및 그의 용도 |
| EP04809112A EP1699779A1 (en) | 2003-12-22 | 2004-12-20 | 1,2,3,4-tetrahydroisoquinoline derivatives, preparations thereof and uses thereof |
| BRPI0417936-6A BRPI0417936A (pt) | 2003-12-22 | 2004-12-20 | composto, um seu sal farmaceuticamente aceitável, diastereÈmeros, enanciÈmeros, ou misturas destes, uso de um composto, composição farmacêutica, métodos para a terapia de dor e de distúrbios gastrintestinais em um animal de sangue quente, e, processo para preparar um composto |
| CA002550643A CA2550643A1 (en) | 2003-12-22 | 2004-12-20 | 1,2,3,4-tetrahydroisoquinoline derivatives, preparations thereof and uses thereof |
| AU2004303736A AU2004303736B2 (en) | 2003-12-22 | 2004-12-20 | 1,2,3,4-tetrahydroisoquinoline derivatives, preparations thereof and uses thereof |
| IL176074A IL176074A0 (en) | 2003-12-22 | 2006-05-31 | 1,2,3,4-tetrahydroisoquinoline derivatives, preparations thereof and uses thereof |
| ZA200605026A ZA200605026B (en) | 2003-12-22 | 2006-06-19 | 1,2,3,4-Tetrahydroisoquinoline derivatives, preparations thereof and uses thereof |
| NO20063353A NO20063353L (no) | 2003-12-22 | 2006-07-19 | 1,2,3,4-tetrahydroisokinolinderivater, fremgangsmate for fremstilling derav og anvendelser derav |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0303542A SE0303542D0 (sv) | 2003-12-22 | 2003-12-22 | 1,2,3,4-Tetrahydroisoquinoline derivaties, preparations thereof and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0303542D0 true SE0303542D0 (sv) | 2003-12-22 |
Family
ID=30768857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0303542A SE0303542D0 (sv) | 2003-12-22 | 2003-12-22 | 1,2,3,4-Tetrahydroisoquinoline derivaties, preparations thereof and uses thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090023728A1 (https=) |
| EP (1) | EP1699779A1 (https=) |
| JP (1) | JP2007515477A (https=) |
| KR (1) | KR20060127903A (https=) |
| CN (1) | CN1918147A (https=) |
| AU (1) | AU2004303736B2 (https=) |
| BR (1) | BRPI0417936A (https=) |
| CA (1) | CA2550643A1 (https=) |
| IL (1) | IL176074A0 (https=) |
| MX (1) | MXPA06007040A (https=) |
| NO (1) | NO20063353L (https=) |
| SE (1) | SE0303542D0 (https=) |
| WO (1) | WO2005061484A1 (https=) |
| ZA (1) | ZA200605026B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105130893B (zh) * | 2015-09-08 | 2018-04-10 | 大连理工大学 | 一种1‑苄基‑6‑甲氧羰甲基四氢异喹啉衍生物、制备方法及其抗血小板聚集的应用 |
| RU2020126188A (ru) * | 2018-01-10 | 2022-02-10 | Альинки Байофарма | Соединения тетрагидроизохинолина |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003218374A1 (en) * | 2002-03-28 | 2003-10-13 | Neurogen Corporation | Substituted tetrahydroisoquinolines as c5a receptor modulators |
-
2003
- 2003-12-22 SE SE0303542A patent/SE0303542D0/xx unknown
-
2004
- 2004-12-20 BR BRPI0417936-6A patent/BRPI0417936A/pt not_active IP Right Cessation
- 2004-12-20 EP EP04809112A patent/EP1699779A1/en not_active Withdrawn
- 2004-12-20 CA CA002550643A patent/CA2550643A1/en not_active Abandoned
- 2004-12-20 US US10/596,546 patent/US20090023728A1/en not_active Abandoned
- 2004-12-20 KR KR1020067014795A patent/KR20060127903A/ko not_active Withdrawn
- 2004-12-20 WO PCT/SE2004/001939 patent/WO2005061484A1/en not_active Ceased
- 2004-12-20 JP JP2006546907A patent/JP2007515477A/ja active Pending
- 2004-12-20 MX MXPA06007040A patent/MXPA06007040A/es unknown
- 2004-12-20 AU AU2004303736A patent/AU2004303736B2/en not_active Ceased
- 2004-12-20 CN CNA200480041965XA patent/CN1918147A/zh active Pending
-
2006
- 2006-05-31 IL IL176074A patent/IL176074A0/en unknown
- 2006-06-19 ZA ZA200605026A patent/ZA200605026B/en unknown
- 2006-07-19 NO NO20063353A patent/NO20063353L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20090023728A1 (en) | 2009-01-22 |
| IL176074A0 (en) | 2006-10-05 |
| JP2007515477A (ja) | 2007-06-14 |
| WO2005061484A1 (en) | 2005-07-07 |
| EP1699779A1 (en) | 2006-09-13 |
| AU2004303736A1 (en) | 2005-07-07 |
| KR20060127903A (ko) | 2006-12-13 |
| BRPI0417936A (pt) | 2007-04-17 |
| CA2550643A1 (en) | 2005-07-07 |
| ZA200605026B (en) | 2007-04-25 |
| AU2004303736B2 (en) | 2008-05-15 |
| MXPA06007040A (es) | 2006-08-31 |
| NO20063353L (no) | 2006-09-06 |
| CN1918147A (zh) | 2007-02-21 |
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