SE0103558D0 - Novel recoverable squaric acid mono esters in bioconjugation chemistry - Google Patents

Novel recoverable squaric acid mono esters in bioconjugation chemistry

Info

Publication number
SE0103558D0
SE0103558D0 SE0103558A SE0103558A SE0103558D0 SE 0103558 D0 SE0103558 D0 SE 0103558D0 SE 0103558 A SE0103558 A SE 0103558A SE 0103558 A SE0103558 A SE 0103558A SE 0103558 D0 SE0103558 D0 SE 0103558D0
Authority
SE
Sweden
Prior art keywords
squaric acid
acid mono
mono esters
bioconjugation chemistry
novel recoverable
Prior art date
Application number
SE0103558A
Other languages
Swedish (sv)
Other versions
SE520256C2 (en
SE0103558L (en
Inventor
Ulf Nilsson
Anders Bergh
Original Assignee
Lundonia Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundonia Biotech Ab filed Critical Lundonia Biotech Ab
Priority to SE0103558A priority Critical patent/SE520256C2/en
Publication of SE0103558D0 publication Critical patent/SE0103558D0/en
Priority to PCT/SE2002/001892 priority patent/WO2003035672A1/en
Priority to EP02802077A priority patent/EP1438328A1/en
Publication of SE0103558L publication Critical patent/SE0103558L/en
Publication of SE520256C2 publication Critical patent/SE520256C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to a biomolecule squaric acid monoamide conjugate of formula (I), as presented in the claims, and to a method for non-polar extraction of a biomolecule squaric acid monoamide conjugate of formula (I), as presented in the claims, obtained after a bioconjugation reaction, wherein said extraction comprises recovering said intermediate by non-polar means.
SE0103558A 2001-10-25 2001-10-25 Biomolekylkvadratsyramonoamidkopplingsreagensintermediär SE520256C2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE0103558A SE520256C2 (en) 2001-10-25 2001-10-25 Biomolekylkvadratsyramonoamidkopplingsreagensintermediär
PCT/SE2002/001892 WO2003035672A1 (en) 2001-10-25 2002-10-25 Novel method for recovery of squaric acid mono esters in bioconjugation chemistry
EP02802077A EP1438328A1 (en) 2001-10-25 2002-10-25 Novel method for recovery of squaric acid mono esters in bioconjugation chemistry

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0103558A SE520256C2 (en) 2001-10-25 2001-10-25 Biomolekylkvadratsyramonoamidkopplingsreagensintermediär

Publications (3)

Publication Number Publication Date
SE0103558D0 true SE0103558D0 (en) 2001-10-25
SE0103558L SE0103558L (en) 2003-04-26
SE520256C2 SE520256C2 (en) 2003-06-17

Family

ID=20285769

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0103558A SE520256C2 (en) 2001-10-25 2001-10-25 Biomolekylkvadratsyramonoamidkopplingsreagensintermediär

Country Status (3)

Country Link
EP (1) EP1438328A1 (en)
SE (1) SE520256C2 (en)
WO (1) WO2003035672A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241883B2 (en) 2001-11-14 2007-07-10 Luminex Corporation Functionalized compositions for improved immobilization
JP5464578B2 (en) * 2009-07-31 2014-04-09 独立行政法人産業技術総合研究所 SSEA novel sugar chain compounds
KR102129148B1 (en) * 2012-05-21 2020-07-01 애질런트 테크놀로지스, 인크. Compositions and methods for conjugating oligonucleotides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4523980A (en) * 1984-08-31 1985-06-18 The Halcon Sd Group, Inc. Process for the recovery of high purity squaric acid
WO2000023478A1 (en) * 1998-10-16 2000-04-27 Amersham Pharmacia Biotech Ab Squaric acid activated carrier usable for immobilisation of compounds containing amine groups

Also Published As

Publication number Publication date
WO2003035672A1 (en) 2003-05-01
SE520256C2 (en) 2003-06-17
EP1438328A1 (en) 2004-07-21
SE0103558L (en) 2003-04-26

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