SA519401589B1 - نظام موائع دقيقة - Google Patents
نظام موائع دقيقةInfo
- Publication number
- SA519401589B1 SA519401589B1 SA519401589A SA519401589A SA519401589B1 SA 519401589 B1 SA519401589 B1 SA 519401589B1 SA 519401589 A SA519401589 A SA 519401589A SA 519401589 A SA519401589 A SA 519401589A SA 519401589 B1 SA519401589 B1 SA 519401589B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- reservoir
- particles
- microfluidic system
- sample
- designed
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/047—Additional chamber, reservoir
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1894—Cooling means; Cryo cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
يتعلق الاختراع الحالي بنظام موائع دقيقة microfluidic system (1) لعزل جسيمات isolation of particles من نوع معين واحد على الأقل ينتمي إلى عينة ويشتمل على وحدة فصل separation unit (3)، والتي يتم تصميمها لنقل الجسيمات من نوع معين من غرفة رئيسية main chamber (4) إلى غرفة استخلاص recovery chamber (5) بطريقة انتقائية إلى حد كبير بالنسبة إلى جسيمات أخرى من العينة؛ وخزان واحد على الأقل (6)، والذي يتم تصميمه لاحتواء سائل ويتم توصيله عن طريق المائع بوحدة الفصل separation unit (3)؛ وتجميعة منظمة regulating assembly (13)، والتي تشتمل على جهاز منظم أول على الأقل (14) به عنصر نقل حرارة heat transfer element أول (15) موضوع عند الخزان الأول (6) لضبط درجة حرارة الخزان الأول (6)، على وجه الخصوص لامتصاص الحرارة من الخزان absorb heat from the reservoir (6). شكل 1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102016000104601A IT201600104601A1 (it) | 2016-10-18 | 2016-10-18 | Sistema microfluidico |
PCT/IB2017/056473 WO2018073760A1 (en) | 2016-10-18 | 2017-10-18 | Microfluidic system |
Publications (1)
Publication Number | Publication Date |
---|---|
SA519401589B1 true SA519401589B1 (ar) | 2022-05-08 |
Family
ID=58010211
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SA519401589A SA519401589B1 (ar) | 2016-10-18 | 2019-04-16 | نظام موائع دقيقة |
Country Status (17)
Country | Link |
---|---|
US (1) | US11077437B2 (ar) |
EP (1) | EP3528948B1 (ar) |
JP (1) | JP7079788B2 (ar) |
KR (1) | KR20190096963A (ar) |
CN (1) | CN109843439B (ar) |
AU (1) | AU2017344470B2 (ar) |
CA (1) | CA3039856A1 (ar) |
DK (1) | DK3528948T3 (ar) |
ES (1) | ES2809166T3 (ar) |
HU (1) | HUE052887T2 (ar) |
IL (1) | IL266141B (ar) |
IT (1) | IT201600104601A1 (ar) |
PT (1) | PT3528948T (ar) |
SA (1) | SA519401589B1 (ar) |
SG (1) | SG11201903259XA (ar) |
SI (1) | SI3528948T1 (ar) |
WO (1) | WO2018073760A1 (ar) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
CA3039857A1 (en) * | 2016-10-18 | 2018-04-26 | Menarini Silicon Biosystems S.P.A. | Microfluidic device, microfluidic system and method for the isolation of particles |
US20210039102A1 (en) * | 2018-02-01 | 2021-02-11 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods and systems for designing and producing nano-structured optical devices |
JP2022517776A (ja) * | 2019-01-25 | 2022-03-10 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | オンラインクロマトグラフィー及びエレクトロスプレーイオン化質量分析装置 |
US20240050957A1 (en) | 2020-12-17 | 2024-02-15 | Totalenergies Onetech | System for controlling the temperature of a microfluidic chip and a microfluidic apparatus for monitoring a substance in a microfluidic chip including such system |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
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IT1309430B1 (it) | 1999-05-18 | 2002-01-23 | Guerrieri Roberto | Metodo ed apparato per la manipolazione di particelle per mezzo delladielettroforesi |
US7485454B1 (en) * | 2000-03-10 | 2009-02-03 | Bioprocessors Corp. | Microreactor |
US6459581B1 (en) * | 2000-12-19 | 2002-10-01 | Harris Corporation | Electronic device using evaporative micro-cooling and associated methods |
JP4698613B2 (ja) * | 2004-01-26 | 2011-06-08 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 流体送達のシステムおよび方法 |
CN101095384A (zh) * | 2004-12-28 | 2007-12-26 | 加利福尼亚州技术学院 | 用于热管理的流体泵 |
CN2767978Y (zh) * | 2005-01-13 | 2006-03-29 | 中国电子科技集团公司第十三研究所 | 纳米尺度的微型温度传感器 |
WO2006081135A2 (en) * | 2005-01-25 | 2006-08-03 | Oscillogy Llc | Temperature controller for small fluid samples having different heat capacities |
CN100491931C (zh) * | 2005-04-14 | 2009-05-27 | 中国科学院电工研究所 | 一种流量检测装置 |
ITBO20050481A1 (it) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | Metodo ed apparato per la manipolazione e/o l'individuazione di particelle |
JP4877710B2 (ja) | 2005-08-01 | 2012-02-15 | 大日本スクリーン製造株式会社 | 液体処理装置および液体供給方法 |
ITBO20050643A1 (it) | 2005-10-24 | 2007-04-25 | Si Bio S R L | Metodo ed apparato per la manipolazione di particelle in soluzioni conduttive |
JP2009544459A (ja) * | 2006-07-20 | 2009-12-17 | ピュリティ アーベー | 液体浄化装置 |
US20110039303A1 (en) | 2007-02-05 | 2011-02-17 | Stevan Bogdan Jovanovich | Microfluidic and nanofluidic devices, systems, and applications |
EP3527288B1 (en) * | 2007-07-23 | 2021-05-12 | Abbott Rapid Diagnostics Jena GmbH | Methods for virus detection |
FI20085299A0 (fi) * | 2008-04-10 | 2008-04-10 | Valtion Teknillinen | Mikrofluidistisia siruvälineitä ja niiden käyttö |
EP2382045A1 (en) * | 2008-12-23 | 2011-11-02 | STMicroelectronics S.r.l. | Method for detecting the presence of liquids in a microfluidic device, detecting apparatus and corresponding microfluidic device |
WO2010077322A1 (en) | 2008-12-31 | 2010-07-08 | Microchip Biotechnologies, Inc. | Instrument with microfluidic chip |
ITBO20090155A1 (it) | 2009-03-17 | 2010-09-18 | Silicon Biosystems Spa | Metodo per l'isolamento di particelle |
ITBO20090154A1 (it) | 2009-03-17 | 2010-09-18 | Silicon Biosystems Spa | Sistema microfluidico |
JP5834001B2 (ja) * | 2009-03-17 | 2015-12-16 | シリコン・バイオシステムズ・ソシエタ・ペル・アチオニ | 細胞を分離するためのマイクロ流体デバイス |
US20120244529A1 (en) * | 2009-04-21 | 2012-09-27 | Martin Fuchs | Multiplex analysis of cells, particles, and other analytes |
JP5337912B2 (ja) | 2009-06-10 | 2013-11-06 | シンベニオ・バイオシステムズ・インコーポレーテッド | シース流装置及び方法 |
CN201600153U (zh) * | 2010-02-08 | 2010-10-06 | 浙江小桥流水环境科技有限公司 | 微型流量开关及其传感器 |
CN102883798B (zh) | 2010-03-22 | 2016-02-24 | 英斯迪罗有限公司 | 用于制备微粒和纳米粒的方法和设备 |
IT1403518B1 (it) | 2010-12-22 | 2013-10-31 | Silicon Biosystems Spa | Dispositivo microfluidico per la manipolazione di particelle |
KR20120091631A (ko) * | 2011-02-09 | 2012-08-20 | 삼성전자주식회사 | 미세유동장치 |
JP6126083B2 (ja) * | 2011-05-17 | 2017-05-10 | キヤノン ユー.エス. ライフ サイエンシズ, インコーポレイテッドCanon U.S. Life Sciences, Inc. | マイクロ流体デバイス内で外部ヒータ・システムを使用するシステムおよび方法 |
CN103667054B (zh) * | 2013-09-18 | 2015-09-30 | 中国航天员科研训练中心 | 一种集成化微流控细胞培养芯片及其制备方法 |
EP3722001A1 (en) * | 2013-11-22 | 2020-10-14 | The General Hospital Corporation | Microfluidic methods and systems for isolating particle clusters |
CN205120530U (zh) * | 2015-11-10 | 2016-03-30 | 信达生物制药(苏州)有限公司 | 一种不溶性微粒检测仪 |
-
2016
- 2016-10-18 IT IT102016000104601A patent/IT201600104601A1/it unknown
-
2017
- 2017-10-18 WO PCT/IB2017/056473 patent/WO2018073760A1/en unknown
- 2017-10-18 DK DK17800613.6T patent/DK3528948T3/da active
- 2017-10-18 ES ES17800613T patent/ES2809166T3/es active Active
- 2017-10-18 SG SG11201903259XA patent/SG11201903259XA/en unknown
- 2017-10-18 HU HUE17800613A patent/HUE052887T2/hu unknown
- 2017-10-18 PT PT178006136T patent/PT3528948T/pt unknown
- 2017-10-18 JP JP2019541902A patent/JP7079788B2/ja active Active
- 2017-10-18 CA CA3039856A patent/CA3039856A1/en active Pending
- 2017-10-18 EP EP17800613.6A patent/EP3528948B1/en active Active
- 2017-10-18 US US16/342,940 patent/US11077437B2/en active Active
- 2017-10-18 AU AU2017344470A patent/AU2017344470B2/en active Active
- 2017-10-18 CN CN201780064746.0A patent/CN109843439B/zh active Active
- 2017-10-18 KR KR1020197013715A patent/KR20190096963A/ko active IP Right Grant
- 2017-10-18 SI SI201730414T patent/SI3528948T1/sl unknown
-
2019
- 2019-04-16 SA SA519401589A patent/SA519401589B1/ar unknown
- 2019-04-18 IL IL266141A patent/IL266141B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IL266141B (en) | 2020-11-30 |
EP3528948A1 (en) | 2019-08-28 |
EP3528948B1 (en) | 2020-07-22 |
IL266141A (en) | 2019-06-30 |
WO2018073760A1 (en) | 2018-04-26 |
AU2017344470A1 (en) | 2019-05-02 |
PT3528948T (pt) | 2020-08-05 |
JP2020500107A (ja) | 2020-01-09 |
AU2017344470B2 (en) | 2022-09-22 |
JP7079788B2 (ja) | 2022-06-02 |
IT201600104601A1 (it) | 2018-04-18 |
US20200055043A1 (en) | 2020-02-20 |
ES2809166T3 (es) | 2021-03-03 |
CN109843439A (zh) | 2019-06-04 |
KR20190096963A (ko) | 2019-08-20 |
SI3528948T1 (sl) | 2020-12-31 |
DK3528948T3 (da) | 2020-08-31 |
CN109843439B (zh) | 2022-12-13 |
HUE052887T2 (hu) | 2021-05-28 |
SG11201903259XA (en) | 2019-05-30 |
CA3039856A1 (en) | 2018-04-26 |
US11077437B2 (en) | 2021-08-03 |
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