RU99112139A - MEMBRANE AND CAMERA OF THE DEVICE FOR DELIVERY OF THE MEDICINAL PRODUCT - Google Patents

MEMBRANE AND CAMERA OF THE DEVICE FOR DELIVERY OF THE MEDICINAL PRODUCT

Info

Publication number
RU99112139A
RU99112139A RU99112139/14A RU99112139A RU99112139A RU 99112139 A RU99112139 A RU 99112139A RU 99112139/14 A RU99112139/14 A RU 99112139/14A RU 99112139 A RU99112139 A RU 99112139A RU 99112139 A RU99112139 A RU 99112139A
Authority
RU
Russia
Prior art keywords
membrane
chamber
polyethylene
layer
outer layer
Prior art date
Application number
RU99112139/14A
Other languages
Russian (ru)
Other versions
RU2193418C2 (en
Inventor
Йорген ФРИИС
Петри ХОРППУ
Original Assignee
Астра Актиеболаг
Данапак Флексибель А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9604162A external-priority patent/SE9604162D0/en
Application filed by Астра Актиеболаг, Данапак Флексибель А/С filed Critical Астра Актиеболаг
Publication of RU99112139A publication Critical patent/RU99112139A/en
Application granted granted Critical
Publication of RU2193418C2 publication Critical patent/RU2193418C2/en

Links

Claims (13)

1. Устройство для выдачи лекарственного средства, включающего смесь первого вещества и второго вещества, содержащее первую камеру (24), вмещающую первое вещество, вторую камеру (30), вмещающую второе вещество, мембрану (28), в ее первом положении приваренную к поверхности первой камеры с обеспечением отсечения первой камеры от второй камеры для предотвращения смешивания первого и второго веществ и имеющую слоистую структуру, содержащую внешний слой (101) материала, которым мембрана приварена к поверхности первой камеры, и механизм (27), выполненный с возможностью приведения в действие для смещения мембраны из первого положения во второе положение, в котором первое и второе вещества могут быть смешаны, при этом по меньшей мере один слой (301) слоистой структуры мембраны содержит барьерный материал, включающий полихлортрифторэтилен или его сополимер, поливинилиденхлорид или его сополимер, или оксид кремния, а внешний слой мембраны и по меньшей мере поверхность первой камеры, к которой он приварен, выполнены соответственно из материалов, обеспечивающих между ними сварное соединение, прочность которого обеспечивает возможность перемещения мембраны во второе положение путем ее отделения от первой камеры, причем указанный механизм выполнен с возможностью обеспечения смещения мембраны при использовании из первого положения во второе положение путем ее отделения от первой камеры.1. A device for dispensing a medicament comprising a mixture of a first substance and a second substance containing a first chamber (24) containing a first substance, a second chamber (30) containing a second substance, a membrane (28), in its first position, welded to the surface of the first chambers providing clipping of the first chamber from the second chamber to prevent mixing of the first and second substances and having a layered structure containing an outer layer (101) of material with which the membrane is welded to the surface of the first chamber, and a mechanism (27) made with the possibility of actuation to move the membrane from the first position to the second position, in which the first and second substances can be mixed, at least one layer (301) of the layered structure of the membrane contains a barrier material including polychlorotrifluoroethylene or its copolymer, polyvinylidene chloride or its copolymer or silicon oxide, and the outer layer of the membrane and at least the surface of the first chamber to which it is welded, respectively, are made of materials that provide a welded connection between them, the strength of which allows the membrane to be moved to the second position by separating it from the first chamber, the mechanism being configured to bias the membrane when used from the first position to the second position by separating it from the first chamber. 2. Устройство по п.1, отличающееся тем, что внешний слой мембраны выполнен из полимера на основе полиэтилена или полимера на основе целлюлозы, а по меньшей мере поверхность первой камеры, к которой приварен внешний слой мембраны, выполнена из полипропилена или его сополимера или из полимера на основе полиэтилена. 2. The device according to claim 1, characterized in that the outer layer of the membrane is made of a polymer based on polyethylene or a polymer based on cellulose, and at least the surface of the first chamber to which the outer layer of the membrane is welded is made of polypropylene or its copolymer or polyethylene based polymer. 3. Устройство по п.1, отличающееся тем, что внешний слой мембраны выполнен из полимера на основе полиэтилена, а по меньшей мере поверхность первой камеры, к которой приварен внешний слой мембраны, выполнена из полиэтилена или полиэтилена высокой плотности. 3. The device according to claim 1, characterized in that the outer layer of the membrane is made of polyethylene based on polymer, and at least the surface of the first chamber to which the outer layer of the membrane is welded is made of high density polyethylene or polyethylene. 4. Устройство по п.2 или 3, отличающееся тем, что внешний слой мембраны выполнен из смеси полиэтилена с этиленвинилацетатом, этиленбутилакрилатом, полибутиленом или бутилакрилатом, сшитым полиэтиленом или иономером полиэтилена. 4. The device according to claim 2 or 3, characterized in that the outer layer of the membrane is made of a mixture of polyethylene with ethylene vinyl acetate, ethylene butyl acrylate, polybutylene or butyl acrylate, crosslinked polyethylene or polyethylene ionomer. 5. Устройство по п.1, отличающееся тем, что внешний слой мембраны выполнен из полипропилена или смеси полипропилена с бутилакрилатом, а по меньшей мере поверхность первой камеры, к которой приварен внешний слой мембраны, выполнена из полипропилена или его сополимера. 5. The device according to claim 1, characterized in that the outer layer of the membrane is made of polypropylene or a mixture of polypropylene with butyl acrylate, and at least the surface of the first chamber to which the outer layer of the membrane is welded is made of polypropylene or its copolymer. 6. Устройство по любому из пп.1-4, отличающееся тем, что барьерный материал содержит полихлортрифторэтилен и образует барьерный слой (301) слоистой структуры, которая включает слой (201) полиэфирного материала, например полиэтилентерефталата, закрепленный на одной из главных поверхностей барьерного слоя. 6. The device according to any one of claims 1 to 4, characterized in that the barrier material contains polychlorotrifluoroethylene and forms a barrier layer (301) of a layered structure, which includes a layer (201) of polyester material, for example polyethylene terephthalate, attached to one of the main surfaces of the barrier layer . 7. Устройство по п. 6, отличающееся тем, что указанный слой полиэфира отделяет барьерный слой от внешнего слоя. 7. The device according to claim 6, characterized in that said polyester layer separates the barrier layer from the outer layer. 8. Устройство по п.6 или 7, отличающееся тем, что указанный слой полиэфира является первым слоем полиэфира, а слоистая структура включает второй слой полиэфира, например, полиэтилентерефталат, прикрепленный к главной поверхности барьерного слоя, противоположной поверхности, на которой закреплен первый слой полиэфира. 8. The device according to claim 6 or 7, characterized in that the polyester layer is the first polyester layer, and the layered structure includes a second polyester layer, for example, polyethylene terephthalate, attached to the main surface of the barrier layer, the opposite surface to which the first polyester layer is attached . 9. Устройство по любому из пп.1-5, отличающееся тем, что оксид кремния включает несущий материал матрицы. 9. The device according to any one of claims 1 to 5, characterized in that the silicon oxide includes a carrier matrix material. 10. Устройство по п.9, отличающееся тем, что материал матрицы выполнен из полиэтилентерефталата. 10. The device according to claim 9, characterized in that the matrix material is made of polyethylene terephthalate. 11. Устройство по любому из пп.1-5, 9 и 10, отличающееся тем, что оксид кремния является диоксидом кремния. 11. The device according to any one of claims 1 to 5, 9 and 10, characterized in that the silicon oxide is silicon dioxide. 12. Устройство по п.2 или 3, отличающееся тем, что первая камера выполнена по существу только из полимера на основе полиэтилена. 12. The device according to claim 2 or 3, characterized in that the first chamber is made essentially only of polymer based on polyethylene. 13. Устройство по любому из предшествующих пунктов, отличающееся тем, что оно выполнено в виде двухкамерного автоматического инъектора. 13. The device according to any one of the preceding paragraphs, characterized in that it is made in the form of a two-chamber automatic injector.
RU99112139/14A 1996-11-13 1997-11-10 Device for giving out medicaments RU2193418C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9604162A SE9604162D0 (en) 1996-11-13 1996-11-13 membrane
SE9604162-9 1996-11-13

Publications (2)

Publication Number Publication Date
RU99112139A true RU99112139A (en) 2001-04-20
RU2193418C2 RU2193418C2 (en) 2002-11-27

Family

ID=20404602

Family Applications (1)

Application Number Title Priority Date Filing Date
RU99112139/14A RU2193418C2 (en) 1996-11-13 1997-11-10 Device for giving out medicaments

Country Status (24)

Country Link
US (1) US6387074B1 (en)
EP (1) EP0944406A1 (en)
JP (1) JP2001507956A (en)
KR (1) KR100463351B1 (en)
CN (1) CN1150947C (en)
AU (1) AU717325B2 (en)
BE (1) BE1012530A5 (en)
CA (1) CA2271476A1 (en)
CZ (1) CZ294849B6 (en)
EG (1) EG21499A (en)
FR (1) FR2755606B1 (en)
GB (1) GB2319184B (en)
IE (1) IE970804A1 (en)
IL (1) IL129874A0 (en)
IT (1) IT1303444B1 (en)
NL (1) NL1007544C2 (en)
NO (1) NO316853B1 (en)
PL (1) PL184764B1 (en)
RU (1) RU2193418C2 (en)
SE (1) SE9604162D0 (en)
TR (1) TR199901043T2 (en)
TW (1) TW383606U (en)
WO (1) WO1998020921A1 (en)
ZA (1) ZA979518B (en)

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