RU99108121A - IMMUNOGENOUS PEPTIDES OF FMD VIRUSES - Google Patents

IMMUNOGENOUS PEPTIDES OF FMD VIRUSES

Info

Publication number
RU99108121A
RU99108121A RU99108121/13A RU99108121A RU99108121A RU 99108121 A RU99108121 A RU 99108121A RU 99108121/13 A RU99108121/13 A RU 99108121/13A RU 99108121 A RU99108121 A RU 99108121A RU 99108121 A RU99108121 A RU 99108121A
Authority
RU
Russia
Prior art keywords
peptides
foot
mouth disease
disease virus
virus
Prior art date
Application number
RU99108121/13A
Other languages
Russian (ru)
Other versions
RU2202613C2 (en
Inventor
Роберто КОРРЕА
Ханс-Роберт ХЕНЕН
Эберхард ПФАФФ
Армин ЗААЛЬМЮЛЛЕР
Томас ПАУЛИ
Беттина ХЕЛИХ
Бернадетте ГЛАТТХААР-ЗААЛЬМЮЛЛЕР
Карл-Хайнц ВИСМЮЛЛЕР
Original Assignee
Байер Акциенгезелльшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19638044A external-priority patent/DE19638044A1/en
Application filed by Байер Акциенгезелльшафт filed Critical Байер Акциенгезелльшафт
Publication of RU99108121A publication Critical patent/RU99108121A/en
Application granted granted Critical
Publication of RU2202613C2 publication Critical patent/RU2202613C2/en

Links

Claims (12)

1. Вакцина против вируса ящура на основе пептидов с последовательностью из, как минимум, восьми аминокислот, соответствующей части последовательности из области неструктурированного белка вируса ящура, которая была отобрана благодаря иммунореактивности с специфичными к вирусу ящура антителами или благодаря иммунореактивности с специфичными к вирусу ящура Т-лимфоцитами.1. A vaccine against foot-and-mouth disease virus based on peptides with a sequence of at least eight amino acids, corresponding to a portion of the sequence from the region of unstructured protein of foot-and-mouth disease virus that was selected due to immunoreactivity with specific for foot-and-mouth disease antibodies or due to immunoreactivity with specific for foot-and-mouth disease virus T- lymphocytes. 2. Вакцина против вируса ящура по п.1, отличающаяся тем, что пептиды содержат от 8 до 35 аминокислот. 2. A vaccine against foot and mouth disease virus according to claim 1, characterized in that the peptides contain from 8 to 35 amino acids. 3. Вакцина против вируса ящура по п.1, отличающаяся тем, что пептиды содержат от 8 до 15 аминокислот. 3. A vaccine against foot and mouth disease virus according to claim 1, characterized in that the peptides contain from 8 to 15 amino acids. 4. Вакцина против вируса ящура по одному из пп.1 - 3, отличающаяся тем, что пептиды соответствуют частям областей на геноме вируса ящура, которые кодируют белки L/L', 2В, 2С, 3А, 3В, 3D. 4. A vaccine against foot and mouth disease virus according to one of claims 1 to 3, characterized in that the peptides correspond to parts of regions on the genome of foot and mouth disease virus that encode proteins L / L ', 2B, 2C, 3A, 3B, 3D. 5. Вакцина против вируса ящура по п.4, отличающаяся тем, что пептиды соответствуют частям областей на геноме вируса ящура, которые кодируют белки 2В, 2С, 3А, 3В. 5. The vaccine against foot and mouth disease virus according to claim 4, characterized in that the peptides correspond to parts of the regions on the genome of foot and mouth disease virus that encode proteins 2B, 2C, 3A, 3B. 6. Пептиды, как определено в любом из пп.1 - 5. 6. Peptides as defined in any one of claims 1 to 5. 7. Пептиды по п.6, которые модифицированы путем сочетания с белковыми носителями или инактивированными вирусами. 7. The peptides according to claim 6, which are modified by combination with protein carriers or inactivated viruses. 8. Последовательности ДНК, кодирующие пептиды по п.6 или 7. 8. DNA sequences encoding the peptides according to claim 6 or 7. 9. Применение вакцины против вируса ящура по п.4 для иммунизации свиней. 9. The use of vaccines against FMD virus according to claim 4 for immunization of pigs. 10. Применение вакцины против вируса ящура по п.5 для иммунизации крупного рогатого скота. 10. The use of vaccines against FMD virus according to claim 5 for immunization of cattle. 11. Применение пептидов по п.6 или 7 в системах детектирования для обнаружения инфицированных вирусом ящура животных, для распознавания вакцинированных и инфицированных животных или для иммунизации животных против заражения вирусом ящура. 11. The use of the peptides according to claim 6 or 7 in detection systems for detecting animals infected with the FMD virus, for recognizing vaccinated and infected animals, or for immunizing animals against infection with the FMD virus. 12. Применение пептидов по п. 6 или 7 для получения систем детектирования для обнаружения инфицированных вирусом ящура животных, распознавания вакцинированных или инфицированных животных или с целью приготовления вакцин для иммунизации животных против заражения вирусом ящура. 12. The use of the peptides according to claim 6 or 7 for the production of detection systems for the detection of FMD virus infected animals, recognition of vaccinated or infected animals, or for the preparation of vaccines for immunizing animals against FMD virus infection.
RU99108121/13A 1996-09-18 1997-09-08 Foot and mouth virus immunogenic peptides RU2202613C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19638044.8 1996-09-18
DE19638044A DE19638044A1 (en) 1996-09-18 1996-09-18 Immunogenic peptides from foot-and-mouth disease viruses

Publications (2)

Publication Number Publication Date
RU99108121A true RU99108121A (en) 2001-05-20
RU2202613C2 RU2202613C2 (en) 2003-04-20

Family

ID=7806008

Family Applications (1)

Application Number Title Priority Date Filing Date
RU99108121/13A RU2202613C2 (en) 1996-09-18 1997-09-08 Foot and mouth virus immunogenic peptides

Country Status (14)

Country Link
US (2) US6984387B1 (en)
EP (1) EP0927256A1 (en)
CN (1) CN1122108C (en)
AR (1) AR009365A1 (en)
AU (1) AU723901B2 (en)
BR (1) BR9712067A (en)
CA (1) CA2265518A1 (en)
DE (1) DE19638044A1 (en)
HK (1) HK1024262A1 (en)
HU (1) HUP9904171A3 (en)
IL (1) IL128847A0 (en)
RU (1) RU2202613C2 (en)
WO (1) WO1998012333A1 (en)
ZA (1) ZA978351B (en)

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FR2810888B1 (en) * 2000-06-29 2004-07-30 Merial Sas VACCINE AGAINST FOOT AND MOUTH DISEASE
US8058248B2 (en) * 2001-04-26 2011-11-15 The United States Of America As Represented By The Secretary Of Agriculture Foot and mouth disease virus vaccine comprising interferons
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
WO2007089571A2 (en) 2006-01-30 2007-08-09 Globoasia, Llc Method of treating chronic kidney disease
US7715679B2 (en) 2007-05-07 2010-05-11 Adc Telecommunications, Inc. Fiber optic enclosure with external cable spool
US8722079B2 (en) * 2008-04-18 2014-05-13 Warsaw Orthopedic, Inc. Methods for treating conditions such as dystonia and post-stroke spasticity with clonidine
RU2453557C1 (en) * 2010-11-03 2012-06-20 Алексей Сергеевич Фолимонов Polyepitope protein composition for inducing immune response against foot-and-mouth disease virus
RU2467014C2 (en) * 2010-12-06 2012-11-20 Учреждение Российской академии наук Центр "Боинженерия" РАН Polyepitope protein, nucleotide sequence coding polyepitope protein, plasmid with sequence coding polyepitope protein, and preparation of polyepitope protein for induction of immune response on murrain virus
CN102998460B (en) * 2012-10-31 2014-12-10 广东海大畜牧兽医研究院有限公司 Enzyme linked immunosorbent assay (ELISA) kit of foot-and-mouth disease virus antibody and preparation method thereof
CN107513101B (en) * 2017-09-18 2021-04-13 中牧实业股份有限公司 Pig foot-and-mouth disease virus non-structural protein antibody enzyme-linked immunoassay kit
CN111744000B (en) * 2020-07-14 2021-03-23 中国农业科学院兰州兽医研究所 Foot-and-mouth disease recombinant virus with reduced immunosuppressive function and preparation method and application thereof
CN117304277B (en) * 2023-09-26 2024-03-08 中国农业科学院兰州兽医研究所 O-type foot-and-mouth disease virus VP4 protein T cell epitope polypeptide and application thereof

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US4140763A (en) * 1976-09-08 1979-02-20 The United States Of America As Represented By The Secretary Of Agriculture Vaccine for foot and mouth disease
ZA831854B (en) * 1982-03-26 1984-01-25 Biogen Nv Small peptides with the specificity of foot and mouth disease viral antigens
WO1983003547A1 (en) * 1982-04-14 1983-10-27 Bittle, James, L. Synthetic picornavirus antigen
US4732971A (en) * 1985-06-03 1988-03-22 Eli Lilly And Company Synthetic vaccines for foot and mouth disease
DE68920735T2 (en) * 1988-03-25 1995-05-24 Mallinckrodt Veterinary Inc Peptides from the foot and mouth disease virus.
US5256641A (en) * 1990-11-01 1993-10-26 State Of Oregon Covalent polar lipid-peptide conjugates for immunological targeting
JP2813768B2 (en) * 1995-05-24 1998-10-22 農林水産省家畜衛生試験場長 Foot-and-mouth disease diagnostic peptide and foot-and-mouth disease diagnostic antigen containing the peptide
US6048538A (en) 1997-10-03 2000-04-11 United Biomedical, Inc. Peptides derived from the non-structural proteins of foot and mouth disease virus as diagnostic reagents

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