RU98116597A - N- (S) -1-Phenyl-1-alkanamide N- (3,3-dimethylbutyl) -l-aspartyl-d-α-aminoalkanoic acid as a sweetener - Google Patents

N- (S) -1-Phenyl-1-alkanamide N- (3,3-dimethylbutyl) -l-aspartyl-d-α-aminoalkanoic acid as a sweetener

Info

Publication number
RU98116597A
RU98116597A RU98116597/04A RU98116597A RU98116597A RU 98116597 A RU98116597 A RU 98116597A RU 98116597/04 A RU98116597/04 A RU 98116597/04A RU 98116597 A RU98116597 A RU 98116597A RU 98116597 A RU98116597 A RU 98116597A
Authority
RU
Russia
Prior art keywords
aspartyl
dimethylbutyl
phenyl
formula
alkanamide
Prior art date
Application number
RU98116597/04A
Other languages
Russian (ru)
Other versions
RU2174983C2 (en
Inventor
Нофр Клод
Тинти Жан-Мари
Original Assignee
Нофр Клод
Тинти Жан-Мари
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9601491A external-priority patent/FR2744454B1/en
Application filed by Нофр Клод, Тинти Жан-Мари filed Critical Нофр Клод
Publication of RU98116597A publication Critical patent/RU98116597A/en
Application granted granted Critical
Publication of RU2174983C2 publication Critical patent/RU2174983C2/en

Links

Claims (1)

1. Соединение формулы:
Figure 00000001

в которой Y является C2H5 или CH(CH3)2 или (R)CH(OH)CH3; и R'' является (S)CH(CH2H5)C6H5, (S)CH(CH3)C6H5 или (R)CH(CH2OCH3)C6H5. 2. Соединение по п.1, отличающееся тем, что оно представляет собой N-(S)-1-фенил-1-пропанамид N-(3,3-диметилбутил)-L-аспартил-D-α-аминомасляной кислоты, имеющей формулу:
Figure 00000002

3. Соединение по п.1, отличающееся тем, что оно представляет собой N-(S)-1-фенил-1-пропанамид N-(3,3-диметилбутил)-L-аспартил-D-валина, имеющей формулу:
Figure 00000003

4. Соединение, по п.1, отличающееся тем, что оно представляет собой N-(S)-1-фенил-2-метокси-1-этанамид N-(3,3-диметилбутил)-L-аспартил-D-α-аминомасляной кислоты, имеющей формулу:
Figure 00000004

5. Соединение по п.1, отличающееся тем, что оно представляет собой N-(S)-1-фенил-2-метокси-1-этинамид N-(3,3-диметилбутил)-L-аспартил-D-валина, имеющей формулу:
Figure 00000005

6. Применение соединений по любому из пп.1 - 5 в качестве подсластитетелей.1. The compound of the formula:
Figure 00000001

in which Y is C 2 H 5 or CH (CH 3 ) 2 or (R) CH (OH) CH 3 ; and R ″ is (S) CH (CH 2 H 5 ) C 6 H 5 , (S) CH (CH 3 ) C 6 H 5 or (R) CH (CH 2 OCH 3 ) C 6 H 5 . 2. The compound according to claim 1, characterized in that it is N- (3,3-dimethylbutyl) -L-aspartyl-D-α-aminobutyric acid N- (S) -1-phenyl-1-propanamide having the formula:
Figure 00000002

3. The compound according to claim 1, characterized in that it is N- (3,3-dimethylbutyl) -L-aspartyl-D-valine N- (S) -1-phenyl-1-propanamide having the formula:
Figure 00000003

4. The compound according to claim 1, characterized in that it is N- (S) -1-phenyl-2-methoxy-1-ethanamide N- (3,3-dimethylbutyl) -L-aspartyl-D-α -aminobutyric acid having the formula:
Figure 00000004

5. The compound according to claim 1, characterized in that it is N- (3,3-dimethylbutyl) -L-aspartyl-D-valine N- (S) -1-phenyl-2-methoxy-1-ethinamide, having the formula:
Figure 00000005

6. The use of compounds according to any one of claims 1 to 5 as sweeteners. 7. Способ получения соединений, по любому из пп.1 - 5, отличающийся тем, что он заключается в обработке восстановителем смеси 3,3-диметилбутиральдегида и соединения, имеющего формулу:
Figure 00000006

в которой Y и R'' - те же, что и определенные в п.1.7. The method of producing compounds according to any one of claims 1 to 5, characterized in that it consists in treating with a reducing agent a mixture of 3,3-dimethylbutyraldehyde and a compound having the formula:
Figure 00000006

in which Y and R '' are the same as defined in claim 1. 8. Способ по п.7, отличающийся тем, что восстановителем является водород при относительном давлении между 1 - 3 бар в присутствии катализатора на основе платины или палладия. 8. The method according to claim 7, characterized in that the reducing agent is hydrogen at a relative pressure between 1 to 3 bar in the presence of a catalyst based on platinum or palladium. 9. Способ, по п.7, отличающийся тем, что восстановителем является цианборгидрид натрия. 9. The method according to claim 7, characterized in that the reducing agent is sodium cyanoborohydride.
RU98116597/04A 1996-02-07 1997-02-07 N-(s)-1-phenyl-1-alkaneamide as sweetening agent RU2174983C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9601491 1996-02-07
FR9601491A FR2744454B1 (en) 1996-02-07 1996-02-07 N- (3,3-DIMETHYLBUTYL) -L-ASPARTYL-D-ALPHA- AMINOALKANOIC ACID N- (S) -1-PHENYL-1-ALCANAMIDE USEFUL AS A SWEETENING AGENT

Publications (2)

Publication Number Publication Date
RU98116597A true RU98116597A (en) 2000-10-10
RU2174983C2 RU2174983C2 (en) 2001-10-20

Family

ID=9488941

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98116597/04A RU2174983C2 (en) 1996-02-07 1997-02-07 N-(s)-1-phenyl-1-alkaneamide as sweetening agent

Country Status (16)

Country Link
US (2) US5777159A (en)
EP (1) EP0879243B1 (en)
JP (1) JP2000505799A (en)
KR (1) KR19990082328A (en)
CN (1) CN1210542A (en)
AR (1) AR005563A1 (en)
AT (1) ATE201695T1 (en)
AU (1) AU708899B2 (en)
BR (1) BR9707377A (en)
DE (1) DE69705024T2 (en)
FR (1) FR2744454B1 (en)
IL (1) IL125256A (en)
NO (1) NO983609L (en)
RU (1) RU2174983C2 (en)
WO (1) WO1997029122A1 (en)
ZA (1) ZA971022B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
JPWO2002062746A1 (en) * 2001-02-08 2004-06-03 味の素株式会社 Novel N-alkyl aspartylamide derivative and sweetener
KR100965662B1 (en) * 2003-01-11 2010-06-24 삼성전자주식회사 Navigation system using paging channel and method for providing traffic information
AR055329A1 (en) * 2005-06-15 2007-08-15 Senomyx Inc BIS-AROMATIC AMIDAS AND ITS USES AS SWEET FLAVORS, FLAVORS, AND FLAVOR ENHANCERS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286509A (en) * 1992-06-22 1994-02-15 The Coca-Cola Company L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners
FR2697844B1 (en) * 1992-11-12 1995-01-27 Claude Nofre New compounds derived from dipeptides or dipeptide analogues useful as sweetening agents, process for their preparation.
FR2719590B1 (en) * 1994-05-09 1996-07-26 Claude Nofre Improved process for the preparation of a compound derived from aspartame useful as a sweetening agent.
FR2719592B1 (en) * 1994-05-09 1996-07-26 Claude Nofre New dipeptide derivatives useful as sweetening agents.

Similar Documents

Publication Publication Date Title
DE69504059D1 (en) IMPROVED METHOD FOR PRODUCING ASPARTAN-BASED COMPOUNDS USED AS A SWEETENER
TR199900307T2 (en) Method and device for high efficiency reverse osmosis process
ATE56756T1 (en) GLUCO-OLIGOSACCHARIDE MIXTURE AND PROCESS FOR ITS PRODUCTION.
BR9307332A (en) Antibacterial mouthwash
DE69609845D1 (en) Process for the preparation of epirubicin or additional salts thereof, of daunorubicin
CA2187502A1 (en) Sweetener salts
RU98116597A (en) N- (S) -1-Phenyl-1-alkanamide N- (3,3-dimethylbutyl) -l-aspartyl-d-α-aminoalkanoic acid as a sweetener
NO975743D0 (en) Process for preparing ioversol
RU2003118330A (en) NEW WAY
FR2591214B1 (en) DEVICE FOR PURIFYING PARTICULARLY SALTED WATER, BY REVERSE OSMOSIS
DK0759030T3 (en) N- [N- (3,3-dimethylbutyl) -L-alpha-aspartyl] -L-hexahydrophenylalanine-1-methyl ester useful as a sweetener and a
RU96123232A (en) 1- METHYL ETHER OF N- [N- (3,3-DIMETHYLBUTYL) -L-α-ASPARTYL] -L- HEXAHYDROPHENYLALANANINE AS A SUGGESTING AGENT AND METHOD FOR ITS PREPARATION
RU95114406A (en) SYRUP CONTAINING N-ACETYL-CYSTEINE
BR9906842A (en) Process for the preparation of 3-buten-1-ol.
RU97120930A (en) POLYMIXIN CONJUGATES
ZA849159B (en) N-(methoxyphenacyl)-amine derivatives
RU98122194A (en) DISINFECTANT
SU1640857A1 (en) Method of regeneration of platinoid catalyst
RU95115371A (en) 5.36: 18,23-DIIMINO-7,10: 13,16: 25,28: 31,34-TETRATIO- [C, S] -DIBENZO-1,6,8,9,14,15,17, 22,24,25,30,31-DODECAAZ-11,12,27,28-TETRATIOCYCLOSODOTYACONTEN TO ELIMINATE Absorption of Strontium and Lead Ions from Aqueous Solutions
ES2139518B1 (en) NEW INSTANT SOLUBILITY SWEETENING COMPOSITIONS IN WATER COMPOSED OF NEOHESPERIDINE DIHIDROCHALCONA WITH ANOTHER OR OTHER HIGH INTENSITY SWEETENERS.
IT9022511A0 (en) PROCESS TO RECOVER PALLADIUM FROM SOLUTIONS POLLUTED BY PB AND CU COMING FROM THE ATTACKING OF EXHAUSTED CATALYST USING REDUCING CARBONYLATION.
Andreev et al. Investigation of degradation processes in MDS-structures at proton irradiation; Issledovanie degradatsionnykh protsessov v MDP-strukturakh pri protonnom obluchenii
KR950017938A (en) Method for producing aspartame by palladium catalytic reduction
Maruta Using Personal-Computer for Estimating Noise
RU95122150A (en) METHOD FOR TREATMENT AND PREVENTION OF ANIMAL SARCOPTOIDOSIS