RU97113691A - ANTI-FILLING EYE DROPS - Google Patents

ANTI-FILLING EYE DROPS

Info

Publication number
RU97113691A
RU97113691A RU97113691/14A RU97113691A RU97113691A RU 97113691 A RU97113691 A RU 97113691A RU 97113691/14 A RU97113691/14 A RU 97113691/14A RU 97113691 A RU97113691 A RU 97113691A RU 97113691 A RU97113691 A RU 97113691A
Authority
RU
Russia
Prior art keywords
eye drops
volume
weight
drops according
polyvinylpyrrolidone
Prior art date
Application number
RU97113691/14A
Other languages
Russian (ru)
Other versions
RU2136252C1 (en
Inventor
Такеути Масанобу
Маруяма Хироки
Сузуки Хирое
Огума Тоуру
Маеда Макото
Original Assignee
Вакамото Фармасьютикал КО., ЛТД
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вакамото Фармасьютикал КО., ЛТД filed Critical Вакамото Фармасьютикал КО., ЛТД
Priority claimed from PCT/JP1995/002680 external-priority patent/WO1996022088A1/en
Publication of RU97113691A publication Critical patent/RU97113691A/en
Application granted granted Critical
Publication of RU2136252C1 publication Critical patent/RU2136252C1/en

Links

Claims (6)

1. Противовоспалительные глазные капли, содержащие (a) 0,05 - 0,7 вес/объемных % диклофенака натрия; (b) 1 - 10 вес/объемных % γ-циклодекстрина; (c) 1 - 20 вес/объемных % поливинилпирролидона; и (d) 0,002 - 0,01 вес/объемных % хлорида бензетония или 0,002 - 0,005 вес/объемных % хлорида бензалкония и имеющие значение pH в интервале от 7 до 8,5.1. Anti-inflammatory eye drops containing (a) 0.05 - 0.7 weight / volume% diclofenac sodium; (b) 1 to 10 weight / volume% γ-cyclodextrin; (c) 1 to 20 weight / volume% polyvinylpyrrolidone; and (d) 0.002-0.01 weight / volume% benzethonium chloride or 0.002-0.005 weight / volume% benzalkonium chloride and having a pH in the range of 7 to 8.5. 2. Глазные капли по п.1, где содержание диклофенака натрия составляет от 0,1 до 0,5 вес/объемных %. 2. Eye drops according to claim 1, where the content of diclofenac sodium is from 0.1 to 0.5 weight / volume%. 3. Глазные капли по п.1 или 2, где содержание γ-циклодекстрина составляет от 3 до 10 вес/объемных %. 3. Eye drops according to claim 1 or 2, where the content of γ-cyclodextrin is from 3 to 10 weight / volume%. 4. Глазные капли по любому одному из пп.1 - 3, где содержание поливинилпирролидона составляет от 2 до 10 вес/объемных %. 4. Eye drops according to any one of claims 1 to 3, where the content of polyvinylpyrrolidone is from 2 to 10 weight / volume%. 5. Глазные капли по любому одному из пп.1 - 4, где значение pH составляет от 7,5 до 8,5. 5. Eye drops according to any one of claims 1 to 4, wherein the pH is from 7.5 to 8.5. 6. Глазные капли по любому одному из пп.1 - 5, где показатель K.Fikentscherea поливинилпирролидона составляет от 10 до 95. 6. Eye drops according to any one of claims 1 to 5, wherein the K.Fikentscherea polyvinylpyrrolidone index is from 10 to 95.
RU97113691/14A 1995-01-20 1995-12-26 Anti-inflammatory ophthalmic drops RU2136252C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7/24485 1995-01-20
JP2448595 1995-01-20
PCT/JP1995/002680 WO1996022088A1 (en) 1995-01-20 1995-12-26 Anti-inflammatory eyedrops

Publications (2)

Publication Number Publication Date
RU97113691A true RU97113691A (en) 1999-06-10
RU2136252C1 RU2136252C1 (en) 1999-09-10

Family

ID=26361998

Family Applications (1)

Application Number Title Priority Date Filing Date
RU97113691/14A RU2136252C1 (en) 1995-01-20 1995-12-26 Anti-inflammatory ophthalmic drops

Country Status (11)

Country Link
US (1) US5929115A (en)
EP (1) EP0807434B1 (en)
JP (1) JP3672569B2 (en)
AT (1) ATE215821T1 (en)
AU (1) AU690794B2 (en)
CA (1) CA2210749C (en)
DE (1) DE69526369T2 (en)
FI (1) FI973060A (en)
NO (1) NO973343L (en)
RU (1) RU2136252C1 (en)
WO (1) WO1996022088A1 (en)

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ATE252369T1 (en) * 1996-08-09 2003-11-15 Alcon Mfg Ltd PRESERVATION SYSTEMS FOR MEDICINAL PRODUCTS CONTAINING CYCLODEXTRINS
JP3450805B2 (en) * 2000-08-08 2003-09-29 わかもと製薬株式会社 Aqueous pharmaceutical composition
US20040013729A1 (en) * 2002-07-18 2004-01-22 Buono Lawrence M. Single-drop multiple-agent composition for topical delivery to the eye
KR20120035220A (en) * 2003-01-22 2012-04-13 센주 세이야꾸 가부시키가이샤 Percutaneous absorption preparation for treating ophthalmic disease, use thereof and method for migration of ophthalmic remedy into topical tissue in eye
KR101144647B1 (en) * 2003-10-31 2012-05-08 와카모토 세이야꾸 가부시끼가이샤 Water-based composition undergoing reversible thermogelation
EP2522343A1 (en) 2006-03-28 2012-11-14 Javelin Pharmaceuticals, Inc. Formulations of Low Dose Diclofenac and Beta-Cyclodextrin
US20070232567A1 (en) * 2006-03-28 2007-10-04 Curtis Wright Formulations Of Low Dose Non-Steroidal Anti-Inflammatory Drugs And Beta-Cyclodextrin
CN103764120A (en) * 2011-06-29 2014-04-30 阿勒根公司 Macrogol 15 hydroxystearate formulations
WO2013149075A1 (en) * 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Compositions and methods for treating or preventing diseases associated with oxidative stress
CN109715215A (en) * 2016-05-06 2019-05-03 沙驰公司 Ophthalmic composition
US11110073B2 (en) * 2017-03-24 2021-09-07 Cadila Healthcare Limited Storage stable aqueous injectable solution comprising diclofenac
EP3675911A1 (en) * 2017-09-01 2020-07-08 Murray & Poole Enterprises, Ltd. Methods and compositions for the treatment of ophthalmic conditions
US11707443B2 (en) 2019-09-26 2023-07-25 Rk Pharma Inc. Storage stable aqueous parenteral solutions comprising diclofenac
JP2024507326A (en) * 2021-01-22 2024-02-19 チョンドゥー ルイムー バイオファーマスーティカルズ カンパニー リミテッド Ophthalmic preparation for preventing and treating dry macular degeneration and retinal photodamage by administering eye drops

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JPS58174309A (en) * 1982-04-06 1983-10-13 Wakamoto Pharmaceut Co Ltd Antiphlogistic eye drop
JPS58174310A (en) * 1982-04-06 1983-10-13 Wakamoto Pharmaceut Co Ltd Antiphlogistic eye drop
JPS5929616A (en) * 1982-08-10 1984-02-16 Kaken Pharmaceut Co Ltd Anti-inflammatory ophthalmic solution and preparation thereof
JPS60136516A (en) * 1983-12-26 1985-07-20 Kaken Pharmaceut Co Ltd Anti-inflammatory ophthalmic liquid and its preparation
DE3612537C1 (en) * 1986-04-14 1987-07-16 Dispersa Ag Medicines used to treat inflammation in the eye
GB8710780D0 (en) * 1987-05-07 1987-06-10 Scras Opthalmological application of eicosapentaenoic acid
JPS6416728A (en) * 1987-07-07 1989-01-20 Santen Pharmaceutical Co Ltd Aqueous preparation
KR950013754B1 (en) * 1987-09-11 1995-11-15 신텍스(미합중국)인코포레이티드 Ophthalmic non-steroid formulations
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
TW200402B (en) * 1990-08-13 1993-02-21 Senju Pharma Co
JPH0616547A (en) * 1992-07-01 1994-01-25 Wakamoto Pharmaceut Co Ltd Antiphlogistic ophthalmic solution
ES2079994B1 (en) * 1992-10-07 1996-08-01 Cusi Lab PHARMACEUTICAL FORMULATION BASED ON POLYMIXINE-TRIMETOPRIM AND AN ANTI-INFLAMMATORY AGENT FOR ITS TOPICAL OPHTHALMIC AND ETHICAL USE.
AU5599594A (en) * 1992-11-16 1994-06-08 Ciba-Geigy Ag Polyvinyl alcohol/borate ophthalmic drug delivery system
RU2049467C1 (en) * 1993-04-16 1995-12-10 Научно-исследовательская фирма "Ультрасан" Antibacterial antiviral preparation
RU2062079C1 (en) * 1993-08-25 1996-06-20 Уфимский научно-исследовательский институт глазных болезней Ophthalmic drops
US5576311A (en) * 1994-11-30 1996-11-19 Pharmos Corporation Cyclodextrins as suspending agents for pharmaceutical suspensions

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