RU97105824A - INHIBITING OR BLOCKING AGENTS OF FUNCTIONS OF MOLECULAR GENERATION AND / OR INDUCTION - Google Patents

Claims (46)

1. Inhibiting or blocking agent of molecular generation and / or induction of functions, represented by formula 1-a:

where (i) R ₁ R ₂ , R ₃ , R ₄ , R ₅ and R ₆ independently represent a hydrogen atom, a halogen atom, a C ₁ -C ₆ alkyl group; an amidino group, a C ₃ -C ₈ cycloalkyl group, a C ₁ -C ₆ alkoxy C ₁ -C ₆ alkyl group, an aryl group, an allyl group, an aralkyl group in which one or more C ₁ -C ₆ alkyl groups are linked to an aromatic ring, selected from the group consisting of a benzene, naphthalene or anthracene ring, a C ₁ -C ₆ alkylene group, a benzoyl group, a cinnamyl group, a cinnamoyl group or a furoyl group,
(ii) A represents a hydrogen atom or

where R ₇ represents a C ₁ -C ₆ alkyl group, a sulfide group or a phosphate group;
R ₈ and R ₉ independently represent a hydrogen atom, a halogen atom, a branched or unbranched C ₁ -C ₆ alkyl group, an aryl group, an allyl group, an aralkyl group in which one or more C ₁ -C ₆ alkyl groups are attached to an aromatic ring, selected from the group consisting of a benzene, naphthalene and anthracene ring, a C ₁ -C ₆ alkylene group, a benzoyl group, a cinnamyl group, a cinnamoyl group or a furoyl group;
(iii) one or more of R ₁ , R ₂ , R ₃ and R ₄ , and / or one or more of R ₅ and R ₆ may be a substituted or unsubstituted cyclopentyl group; a substituted or unsubstituted cyclohexyl group, or a substituted or unsubstituted naphthyl group;
(iv) R ₅ and R ₆ can form a ring by linking to another fused polycyclic hydrocarbon compound or heterocyclic compound;
(v) one or more of R ₃ , R ₄ , R ₅ and R ₆ may be substituted by one or more substituents selected from the group consisting of a halogen atom, a cyano group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, protected or unprotected amino group, C ₁ -C ₆ alkyl group, C ₁ -C ₆ alkoxy group, C ₁ -C ₇ alkoxycarbonyl group, aryl group, C ₃ -C ₆ cycloalkyl group, C ₁ -C ₆ acylamino group, C ₁ -C ₆ acyloxy group , C ₂ -C ₆ alkenyl group, C ₁ -C ₆ trihaloalkyl group, C ₁ -C ₆ alkylamino Ruppu and C ₁ -C ₆ dialkylamino group,
(vi) R ₂ and / or R ₅ may be substituted with one or more substituents selected from the group consisting of a halogen atom, a C ₁ -C ₆ alkyl group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, protected or unprotected an amino group, a protected or unprotected C ₁ -C ₆ alkylamino group, a protected or unprotected C ₁ -C ₆ aminoalkyl group, a protected or unprotected C ₁ -C ₆ alkylamino C ₁ -C ₆ alkyl group, a protected or unprotected hydroxyalkyl group, and a C ₃ -C ₆ cycloal kilamino groups;
(vii) when one or more of R ₃ , R ₄ , R ₅ and R ₆ represents an alkyl group, the terminal end (s) of the alkyl group (s) may be substituted with a C ₃ -C ₈ cycloalkyl group.  2. An inhibitory or blocking agent for molecular generation and / or induction of functions, according to claim 1, wherein said aryl group in (i), (ii) and (v) is a phenyl, tolyl or naphthyl group; said substituted cyclopentyl group in (iii) is a cyclopentylamino group or cyclopentylcarbinol group, said substituted cyclohexyl group in (iii) is a cyclohexylamino group, cyclohexylaldehyde group or cyclohexyl group of acetic acid, and said substituted naphthyl group in (iii) is a naphthylamino acid group or said condensed polycyclic hydrocarbon compound in (iv) is pentalene, indene, naphthalene, azulene, heptalene, bifeni ene, indacene, acenaphthylene, fluorene, phenalen, phenanthrene, anthracene, pentacene, hexacene, dibenzophenanthrene, 1H-cyclopentacyclooctene or benzocyclooctene, and said heterocyclic compound is furan, thiophene, pyrrole, γ-pyran, γ-thiopyrazole, pyriza, piriol, pyrimidine, indole or quinoline. 3. Inhibiting or blocking agent of molecular generation and / or induction of functions, represented by formula 1-b:

where (i) R ₁ , R ₂ , R ₃ , R ₄ , R ₅ , R ₆ , R ₁₀ and R ₁₁ independently represents a hydrogen atom, a halogen atom; A C ₁ -C ₆ alkyl group; amidino group; A C ₃ -C ₈ cycloalkyl group; C ₁ -C ₆ alkoxy C ₁ -C ₆ alkyl group; an aryl group; allyl group; an aralkyl group in which one or more C ₁ -C ₆ alkyl groups are linked to an aromatic ring selected from the group consisting of a benzene, naphthalene or anthracene ring; a group C ₁ -C ₆ alkylene; benzoyl group; cinnamyl group; cinnamoyl group; furoyl group;
(ii) A represents a hydrogen atom or

where R ₇ represents a C ₁ -C ₆ alkyl group; a sulfide group or a phosphate group;
R ₈ and R ₉ independently represent a hydrogen atom; halogen atom; a branched or unbranched group, a C ₁ -C ₆ alkyl group; an aryl group; allyl group; an aralkyl group in which one or more C ₁ -C ₆ alkyl groups bind to an aromatic ring selected from the group consisting of a benzene, naphthalene and anthracene ring; A C ₁ -C ₆ alkylene group; benzoyl group; cinnamyl group; a cinnamoyl group or a furoyl group;
(iii) one or more of R ₁ , R ₂ , R ₃ and R ₄ , and / or one or more of R ₅ , R ₆ , R ₁₀ and R ₁₁ may be a substituted or unsubstituted cyclopentyl group; substituted or unsubstituted cyclohexyl group; or a substituted or unsubstituted naphthyl group;
(iv) R ₅ , R ₆ , R ₁₀ and R ₁₁ can form a ring by linking to another fused polycyclic hydrocarbon compound or heterocyclic compound;
(v) one or more of R ₃ , R ₄ , R ₅ , R ₆ , R ₁₀ and R ₁₁ may be substituted with one or more substituents selected from the group consisting of a halogen atom, a cyano group, a protected or unprotected carboxyl group, protected or unprotected hydroxyl group, protected or unprotected amino group, C ₁ -C ₆ alkyl group, C ₁ -C an alkoxy group of C ₁ -C ₇ alkoxycarbonyl, aryl, C ₃ -C ₆ cycloalkyl group, a C ₁ -C ₆ acylamino, C ₁ -C ₆ -atsiloksigruppu, C ₂ -C ₆ alkenyl group, a C ₁ -C ₆ trigalogenalkilnuyu a group, a C ₁ -C ₆ alkylamino group and a C ₁ -C ₆ dialkylamino group;
(vi) R ₂ and / or R ₅ may be substituted with one or more substituents selected from the group consisting of a halogen atom, a C ₁ -C ₆ alkyl group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, protected or unprotected an amino group, a protected or unprotected C ₁ -C ₆ alkylamino group, a protected or unprotected C ₁ -C ₆ aminoalkyl group, a protected or unprotected C ₁ -C ₆ alkylamino C ₁ -C ₆ alkyl group, a protected or unprotected hydroxyalkyl group and a C ₃ -C ₆ cycloalkyl minogroups;
(vii) when one or more of R ₃ , R ₄ , R ₅ , R ₆ , R ₁₀ and R ₁₁ represents an alkyl group, the terminal end (s) of the alkyl group (s) may be substituted with a C ₃ -C ₈ cycloalkyl group.  4. The inhibitory or blocking agent for molecular generation and / or induction of functions according to claim 3, wherein said aryl group in (i), (ii) and (v) is a phenyl, tolyl or naphthyl group; said substituted cyclopentyl group in (iii) is a cyclopentylamino group or a cyclopentylcarbinol group, said substituted cyclohexyl group in (iii) is a cyclohexylamino group, a cyclohexylaldehyde group or a cyclohexyl group of acetic acid, and said substituted naphthyl group in (iii) is a naphthylamino acid sulfonate group condensed polycyclic hydrocarbon in (iv) is pentalene, indene, naphthalene, azulene, heptalene, biphenylene, indacene, acenaphthylene, fl Oren, phenalene, phenanthrene, anthracene, pentacene, hexacene, dibenzofenantren, 1H-cyclopentacyclooctene or benzotsiklookten, and said heterocyclic compound is furan, thiophene, pyrrole, γ-pyran, γ-thiopyran, pyridine, thiazole, imidazole pyrimidine, indole or quinoline. 5. Inhibiting or blocking agent of molecular generation and / or induction of functions, represented by formula 2

where (i) R ₁ , R ₂ , R ₃ , R ₄ , R ₅ and R ₆ independently represent a hydrogen atom; halogen atom; A C ₁ -C ₆ alkyl group; amidino group; A C ₃ -C ₈ cycloalkyl group; C ₁ -C ₆ alkoxy C ₁ -C ₆ alkyl group; an aryl group; allyl group; an aralkyl group in which one or more C ₁ -C ₆ alkyl groups are linked to an aromatic ring selected from the group consisting of a benzene, naphthalene or anthracene ring; a group C ₁ -C ₆ alkylene; benzoyl group; cinnamyl group; a cinnamoyl group or a furoyl group;
(ii) one or more of R ₁ , R ₂ , R ₃ and R ₄ and / or one or more of R ₅ and R ₆ may be a substituted or unsubstituted cyclopentyl group; substituted or unsubstituted cyclohexyl group; or a substituted or unsubstituted naphthyl group;
(iii) R ₅ and R ₆ can form a ring by binding to another compound of a fused polycyclic hydrocarbon or heterocyclic compound;
(iv) one or more of R ₃ , R ₄ , R ₅ and R ₆ may be substituted by one or more substituents selected from the group consisting of a halogen atom, a cyano group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, protected or unprotected amino group, C ₁ -C ₆ alkyl group, C ₁ -C ₆ alkoxy group, C ₁ -C ₇ alkoxycarbonyl group, aryl group, C ₃ -C ₆ cycloalkyl group, C ₁ -C ₆ acylamino group, C ₁ -C ₆ acyloxy group , C ₂ -C ₆ alkenyl group, C ₁ -C ₆ trihaloalkyl group, C ₁ -C ₆ alkyl a minogroup and a C ₁ -C ₆ dialkylamino group;
(v) R ₂ and / or R ₅ may be substituted with one or more substituents selected from the group consisting of a halogen atom, a C ₁ -C ₆ alkyl group, a protected or unprotected carboxyl group, a protected or unprotected hydroxy group, a protected or unprotected amino group, protected or unprotected C ₁ -C ₆ alkylamino group, a protected or unprotected C ₁ -C ₆ aminoalkyl group, a protected or unprotected C ₁ -C ₆ alkylamino C ₁ -C ₆ alkyl group, a protected or unprotected hydroxyalkyl group, and _C3-C6 tsikloalkilaminogru pp;
(vi) when one or more of R ₃ , R ₄ , R ₅ and R ₆ represents an alkyl group, the terminal end (s) of the alkyl group (s) may be substituted with a C ₃ -C ₈ cycloalkyl group. 6. The inhibitory or blocking agent for molecular generation and / or induction of functions according to claim 5, wherein said aryl group in (i) and (iv) is a phenyl, tolyl, xylyl or naphthyl group; said substituted cyclopentyl group in (ii) is a cyclopentylamino group or a cyclopentylcarbinol group, said substituted cyclohexyl group in (ii) is a cyclohexylamino group, a cyclohexylaldehyde group or cyclohexylacetic acid group, and said substituted naphthyl group in (ii) is a naphthylamino acid group;
and said condensed polycyclic hydrocarbon compound in (iii) is pentalene, indene, naphthalene, azulene, heptalene, biphenylene, indacene, acenaphthylene, fluorene, phenalen, phenanthrene, anthracene, pentacene, hexacene, dibenzophenanthrene, 1H-cyclopentacyclooctene or benzocyclic the compound is furan, thiophene, pyrrole, γ-pyran, γ-thiopyran, pyridine, thiazole, imidazole pyrimidine, indole or quinoline. 7. Inhibiting or blocking agent of molecular generation and / or induction of functions, represented by formula 3-a

where (i) R ₃ , R ₄ , R ₅ and R ₆ independently represent a hydrogen atom; halogen atom; WITH A -C6 alkyl group; amidino group; A C ₃ -C ₈ cycloalkyl group; C ₁ -C ₆ alkoxy C ₁ -C ₆ alkyl group; an aryl group; allyl group; an aralkyl group in which one or more C ₁ -C ₆ alkyl groups are linked to an aromatic ring selected from the group consisting of a benzene, naphthalene or anthracene ring; a group C ₁ -C ₆ alkylene; benzoyl group; cinnamyl group; a cinnamoyl group or a furoyl group;
(ii) one or more of R ₃ and R ₄ and / or one or more of R ₅ and R ₆ may be a substituted or unsubstituted cyclopentyl group; substituted or unsubstituted cyclohexyl group; or a substituted or unsubstituted naphthyl group;
(iii) R ₅ and R ₆ can form a ring by binding to another polycyclic hydrocarbon condensation compound or a heterocyclic compound;
(iv) one or more of R ₃ , R ₄ , R ₅ and R ₆ may be substituted by one or more substituents selected from the group consisting of a halogen atom, a cyano group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, protected or unprotected amino group, C ₁ -C ₆ alkyl group, C ₁ -C ₆ alkoxy group, C ₁ -C ₇ alkoxycarbonyl group, aryl group, C ₃ -C ₆ cycloalkyl group, C ₁ -C ₆ acylamino group, C ₁ -C ₆ acyloxy group, C ₂ -C ₆ alkenyl group, C ₁ -C ₆ trihaloalkyl group, C ₁ -C ₆ alkyl a minogroup and a C ₁ -C ₆ dialkylamino group;
(v) R ₅ may be substituted by one or more substituents selected from the group consisting of a halogen atom, a C ₁ -C ₆ alkyl group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, a protected or unprotected amino group, protected or unprotected C ₁ -C ₆ alkylamino group, a protected or unprotected C ₁ -C ₆ aminoalkyl group, a protected or unprotected C ₁ -C ₆ alkylamino C ₁ -C ₆ alkyl group, a protected or unprotected hydroxyalkyl group, and _C3-C6 cycloalkylamino Rupp;
(vi) when one or more of R ₃ , R ₄ , R ₅ and R ₆ represents an alkyl group, the terminal end (s) of the alkyl group (s) may be substituted with a C ₃ -C ₈ cycloalkyl group.  8. The inhibitory or blocking agent for molecular generation and / or induction of functions according to claim 7, wherein said aryl group in (i) and (iv) is a phenyl, tolyl, xylyl or naphthyl group; said substituted cyclopentyl group in (ii) is a cyclopentylamino group or a cyclopentylcarbinol group, said substituted cyclohexyl group in (ii) is a cyclohexylamino group, a cyclohexylaldehyde group or cyclohexylacetic acid group and said substituted naphthyl group in (ii) is a naphthylamino-amino group or and said condensed polycyclic hydrocarbon compound in (iii) is pentalene, indene, naphthalene, azulene, heptalene, biphenylene, indacene, acenaphthylene, fluorene, phenalen, phenanthrene, anthracene, pentacene, hexacene, dibenzofenanthrene, 1H-cyclopentacyclooctene or benzocyclic the compound is furan, thiophene, pyrrole, γ-pyran, γ-thiopyran, pyridine, thiazole, imidazole pyrimidine, indole and quinoline. 9. The inhibitory or blocking agent for molecular generation and / or induction of functions according to claim 7, where R ₃ , R ₄ , R ₅ and R ₆ represent hydrogen atoms. 10. Inhibiting or blocking agent of molecular generation and / or induction of functions represented by formula 3-b

where (i) R ₃ , R ₄ , R ₅ and R ₆ independently represent a hydrogen atom; halogen atom; A C ₁ -C ₆ alkyl group; amidino group; A C ₃ -C ₈ cycloalkyl group; C ₁ -C ₆ alkoxy C ₁ -C ₆ alkyl group; an aryl group; allyl group; an aralkyl group in which one or more C ₁ -C ₆ alkyl groups are linked to an aromatic ring selected from the group consisting of a benzene, naphthalene or anthracene ring; a group C ₁ -C ₆ alkylene; benzoyl group; cinnamyl group; a cinnamoyl group or a furoyl group;
(ii) one or more of R ₃ and R ₄ and / or one or more of R ₅ and R ₆ may be a substituted or unsubstituted cyclopentyl group; substituted or unsubstituted cyclohexyl group; or a substituted or unsubstituted naphthyl group;
(iii) R ₅ and R ₆ can form a ring by binding to another polycyclic hydrocarbon condensation compound or a heterocyclic compound;
(iv) one or more of R ₃ , R ₄ , R ₅ and R ₆ may be substituted by one or more substituents selected from the group consisting of a halogen atom, a cyano group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, protected or unprotected amino group, C ₁ -C ₆ alkyl group, C ₁ -C ₆ alkoxy group, C ₁ -C ₇ alkoxycarbonyl group, aryl group, C ₃ -C ₆ cycloalkyl group, C ₁ -C ₆ acylamino group, C ₁ -C ₆ acyloxy group , C ₂ -C ₆ alkenyl group, C ₁ -C ₆ trihaloalkenyl group, C ₁ -C ₆ alkylamino ppu and C ₁ -C ₆ dialkylamino;
(v) R ₅ may be substituted by one or more substituents selected from the group consisting of a halogen atom, a C ₁ -C ₆ alkyl group, a protected or unprotected carboxyl group, a protected or unprotected hydroxyl group, a protected or unprotected amino group, a protected or unprotected C ₁ -C ₆ alkylamino group, a protected or unprotected C ₁ -C ₆ aminoalkyl group, a protected or unprotected C ₁ -C ₆ alkylamino C ₁ -C ₆ alkyl group, a protected or unprotected hydroxyalkyl group, and a C ₃ -C ₆ cycloalkylamino group;
(vi) when one or more of R ₃ , R ₄ , R ₅ and R ₆ represents an alkyl group, the terminal end (s) of the alkyl group (s) may be substituted with a C ₃ -C ₈ cycloalkyl group. 11. The inhibitory or blocking agent for molecular generation and / or induction of functions according to claim 10, wherein said aryl group in (i) and (iv) is a phenyl, tolyl, xylyl or naphthyl group; said substituted cyclopentyl group in (ii) is a cyclopentylamino group or a cyclopentylcarbinol group, said substituted cyclohexyl group in (ii) is a cyclohexylamino group, a cyclohexylaldehyde group or a cyclohexylacetic acid group, and said substituted naphthyl group in (ii) is a naphthylamino-amino group or and said condensed polycyclic hydrocarbon compound in
(iii) represents pentalene, indene, naphthalene, azulene, heptalene, biphenylene, indacene, acenaphthylene, fluorene, phenalene, phenanthrene, anthracene, pentacene, hexacene, dibenzophenanthrene, 1H-cyclopentacyclooctene or benzocyclooctene and, said heterocyclic phenyl compound, represents , γ-pyran, γ-thiopyran, pyridine, thiazole, imidazole pyrimidine, indole or quinoline.  12. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an antibacterial agent.  13. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an antifungal agent.  14. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an antiviral agent.  15. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a bactericidal and / or sterilizing agent.  16. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an anticancer agent and / or an antitumor agent.  17. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an anticoagulant and / or antifibrinolytic agent.  18. An inhibitory or blocking agent for molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an antigen-antibody inhibitory and / or blocking agent.  19. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which represents a preservative of organ and tissue.  20. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an antiseptic and / or preservative.  21. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which represents a labeled reagent that has a labeled substance in at least one substituent, the labeled substance of which indicates the marked position of the generated function of the molecule.  22. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a reducing agent.  23. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which represents a free radical scavenger.  24. Inhibiting or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a desulfurization agent.  25. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a depolymerizing agent.  26. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for improving the functional and / or physical properties of a surfactant.  27. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a spermatocidal agent or contraceptive agent for external use.  28. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a thrombolytic agent.  29. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent that changes the conformation of saccharide chains.  30. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for preventing atherosclerosis.  31. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for improving metabolism (lipids, sugars, proteins).  32. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for wound healing or an agent that promotes epithelization (including the effect of hair restoration).  33. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for a phase transition or an agent that improves the phase transition.  34. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for improving the microphase separation structure.  35. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a plasticizer or agent for improving ductility and / or elasticity.  36. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a copolymerization agent or an agent for improving copolymerization.  37. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a polymerization regulator or an agent that improves the regulation of polymerization.  38. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a stabilizer or stabilizing agent.  39. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an antioxidant or an anti-oxidation agent.  40. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent that improves crystalline materials and / or amorphous materials.  41. Inhibitory or blocking agent molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent that improves the fluidity.  42. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is a softener or agent that improves softness and / or flexibility.  43. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent for modulating and / or improving the fluorescence wavelength and / or excitation wavelength of pigments, coating materials, paints or dyes.  44. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent that improves the functional and / or physical properties of low molecular weight substances.  45. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent that improves the physical properties and functions of macromolecular substances.  46. The inhibitory or blocking agent of molecular generation and / or induction of functions according to any one of paragraphs. 1-11, which is an agent that improves the physical properties of macromolecular composite materials and the functions of macromolecular composite materials.