RU97100774A - MANIPULATION BY PROPOSAL ACTIVITY OF PROTOPORPHIRINOGEN-OXIDASE IN EUCARIOT - Google Patents

MANIPULATION BY PROPOSAL ACTIVITY OF PROTOPORPHIRINOGEN-OXIDASE IN EUCARIOT

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RU97100774A
RU97100774A RU97100774/13A RU97100774A RU97100774A RU 97100774 A RU97100774 A RU 97100774A RU 97100774/13 A RU97100774/13 A RU 97100774/13A RU 97100774 A RU97100774 A RU 97100774A RU 97100774 A RU97100774 A RU 97100774A
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plant
dna molecule
protox
activity
group
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RU97100774/13A
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RU2192468C2 (en
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Рассел Ворд Эрик
Волрэт Сандра
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Новартис Аг
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1. Выделенная молекула ДНК, кодирующая протеин из эукариота, обладающий активностью протопорфириноген-оксидазы (протокса).1. The selected DNA molecule encoding a protein from eukaryote, with the activity of protoporphyrinogen-oxidase (protox). 2. Выделенная молекула ДНК по п. 1, где эукариот представляет собой высший эукариот. 2. The selected DNA molecule under item 1, where the eukaryote is the highest eukaryote. 3. Выделенная молекула ДНК по п.2, где высший эукариот представляет собой растение. 3. The selected DNA molecule according to claim 2, where the highest eukaryote is a plant. 4. Выделенная молекула ДНК по п. 3, где растение представляет собой двудольное растение. 4. The selected DNA molecule under item 3, where the plant is a dicotyledonous plant. 5. Выделенная молекула ДНК по п.4, где двудольное растение представляет собой виды p. Arabidopsis. 5. The selected DNA molecule according to claim 4, where the bichromatic plant is a species p. Arabidopsis. 6. Выделенная молекула ДНК по п.5, где протеин содержит аминокислотную последовательность, выбранную из группы, состоящей из SEQ ID NO: 2 и SEQ ID NO: 4. 6. The selected DNA molecule according to claim 5, where the protein contains an amino acid sequence selected from the group consisting of SEQ ID NO: 2 and SEQ ID NO: 4. 7. Выделенная молекула ДНК по п.3, где растение представляет собой однодольное растение. 7. The selected DNA molecule according to claim 3, where the plant is a monocotyledonous plant. 8. Выделенная молекула ДНК по п.7, где однодольное растение представляет собой кукурузу. 8. The selected DNA molecule according to claim 7, where the monocotyledonous plant is a corn. 9. Выделенная молекула ДНК по п.8, где протеин содержит аминокислотную последовательность, выбранную из группы, состоящей из SEQ ID NO: 6 и SEQ ID NO: 8. 9. The selected DNA molecule of claim 8, where the protein contains an amino acid sequence selected from the group consisting of SEQ ID NO: 6 and SEQ ID NO: 8. 10. Молекула ДНК, кодирующая модифицированный фермент протопорфириноген-оксидазу (протокс), содержащий эукариотический протокс, имеющий по крайней мере одну аминокислотную модификацию, причем модифицированный протокс обладает толерантностью к гербициду в таких его количествах, которые ингибируют эукариотический протокс. 10. A DNA molecule encoding a modified protoporphyrinogen oxidase (protox) enzyme containing a eukaryotic protox having at least one amino acid modification, the modified protox having herbicide tolerance in such quantities that inhibit the eukaryotic protox. 11. Молекула ДНК по п.10, где эукариотический протокс имеет происхождение из растения. 11. The DNA molecule of claim 10, where the eukaryotic protox is derived from a plant. 12. Молекула ДНК по п.11, где растение представляет собой двудольное растение. 12. The DNA molecule according to claim 11, where the plant is a dicotyledonous plant. 13. Молекула ДНК по п.12, где двудольное растение представляет собой виды p. Arabidopsis. 13. The DNA molecule indicated in paragraph 12, where the bichromatic plant is a species p. Arabidopsis. 14. Молекула ДНК по п.13, где эукариотический протокс содержит аминокислотную последовательность, выбранную из группы, состоящей из SEQ ID NO: 2 и SEQ ID NO: 4. 14. The DNA molecule according to claim 13, wherein the eukaryotic protox contains an amino acid sequence selected from the group consisting of SEQ ID NO: 2 and SEQ ID NO: 4. 15. Молекула ДНК по п.14, где эукариотический протокс содержит аминокислотную последовательность, представленную в SEQ ID NO: 2. 15. The DNA molecule of claim 14, wherein the eukaryotic protox contains the amino acid sequence shown in SEQ ID NO: 2. 16. Молекула ДНК по п.15, где по крайней мере одна аминокислотная модификация представляет собой замещение аминокислоты, выбранной из группы, состоящей из аланина в положении 220, глицина в положении 221 и тирозина в положении 426 в SEQ ID NO: 2. 16. The DNA molecule according to claim 15, wherein at least one amino acid modification is a substitution of an amino acid selected from the group consisting of alanine at position 220, glycine at position 221 and tyrosine at position 426 in SEQ ID NO: 2. 17. Молекула ДНК по п.16, где аланин в положении 220 замещают на аминокислоту, выбранную из группы, состоящей из валина, треонина, лейцина, цистеина и тирозина. 17. The DNA molecule according to claim 16, wherein the alanine at position 220 is replaced by an amino acid selected from the group consisting of valine, threonine, leucine, cysteine and tyrosine. 18. Молекула ДНК по п.16, где глицин в положении 221 замещают на серин. 18. The DNA molecule according to claim 16, where the glycine at position 221 is replaced by serine. 19. Молекула ДНК по п.16, где тирозин в положении 426 замещают на аминокислоту, выбранную из группы, состоящей из цистеина, изолейцина, лейцина и треонина. 19. The DNA molecule according to claim 16, wherein the tyrosine at position 426 is replaced by an amino acid selected from the group consisting of cysteine, isoleucine, leucine and threonine. 20. Молекула ДНК по п.11, где растение представляет собой однодольное растение. 20. The DNA molecule according to claim 11, where the plant is a monocotyledonous plant. 21. Молекула ДНК по п.20, где однодольное растение представляет собой кукурузу. 21. The DNA molecule according to claim 20, where the monocotyledonous plant is corn. 22. Молекула ДНК по п.21, где эукариотический протокс содержит аминокислотную последовательность, выбранную из группы, состоящей из SEQ ID NO: 6 и SEQ ID NO: 8. 22. The DNA molecule according to claim 21, wherein the eukaryotic protox contains an amino acid sequence selected from the group consisting of SEQ ID NO: 6 and SEQ ID NO: 8. 23. Молекула ДНК по п.22, где эукариотический протокс содержит аминокислотную последовательность, представленную в SEQ ID NO: 6. 23. The DNA molecule of claim 22, wherein the eukaryotic protox contains the amino acid sequence shown in SEQ ID NO: 6. 24. Молекула ДНК по п.23, где по крайней мере одна аминокислотная модификация представляет собой замещение аминокислоты, выбранной из группы, состоящей из аланина в положении 166, глицина в положении 167 и тирозина в положении 372 в SEQ ID NO: 6. 24. The DNA molecule of claim 23, wherein at least one amino acid modification is a substitution of an amino acid selected from the group consisting of alanine at position 166, glycine at position 167 and tyrosine at position 372 in SEQ ID NO: 6. 25. Молекула ДНК по п.24, где аланин в положении 166 замещают на аминокислоту, выбранную из группы, состоящей из валина, треонина, лейцина, цистеина и тирозина. 25. The DNA molecule in paragraph 24, where the alanine at position 166 is replaced by an amino acid selected from the group consisting of valine, threonine, leucine, cysteine and tyrosine. 26. Молекула ДНК по п.24, где глицин в положении 167 замещают на серин. 26. The DNA molecule in paragraph 24, where the glycine at position 167 is replaced by serine. 27. Молекула ДНК по п.24, где тирозин в положении 372 замещают на аминокислоту, выбранную из группы, состоящей из цистеина, изолейцина, лейцина и треонина. 27. The DNA molecule in paragraph 24, where the tyrosine at position 372 is replaced by an amino acid selected from the group consisting of cysteine, isoleucine, leucine and threonine. 28. Молекула ДНК по любому пп.10 - 27, которая представляет собой часть генома растения. 28. A DNA molecule according to any of claims 10 to 27, which is a part of the plant genome. 29. Химерный ген, содержащий промотор, действенным образом сцепленный с гетерологичной молекулой ДНК, кодирующей протеин из высшего эукариота, обладающий активностью протопорфириноген-оксидазы (протокса). 29. Chimeric gene containing a promoter, effectively linked to a heterologous DNA molecule that encodes a protein from higher eukaryotes, with the activity of protoporphyrinogen oxidase (protox). 30. Химерный ген по п.29, где промотор обладает активностью в растении. 30. The chimeric gene according to clause 29, where the promoter has activity in the plant. 31. Химерный ген по п.30, дополнительно содержащий сигнальную последовательность, действенным образом сцепленную с молекулой ДНК, причем сигнальная последовательность обладает способностью направить протеин, кодируемый молекулой ДНК, в хлоропласт. 31. The chimeric gene of claim 30, further comprising a signal sequence effectively linked to the DNA molecule, wherein the signal sequence has the ability to direct the protein encoded by the DNA molecule into the chloroplast. 32. Химерный ген по п.30, дополнительно содержащий сигнальную последовательность, действенным образом сцепленную с молекулой ДНК, причем сигнальная последовательность обладает способностью направлять протеин, кодируемый молекулой ДНК, в митохондрии. 32. The chimeric gene of claim 30, further comprising a signal sequence effectively linked to the DNA molecule, the signal sequence having the ability to direct the protein encoded by the DNA molecule into the mitochondria. 33. Химерный ген, содержащий промотор, обладающий активностью в растении и действенным образом сцепленный с молекулой ДНК по п.10. 33. A chimeric gene containing a promoter that is active in a plant and is efficiently linked to a DNA molecule according to claim 10. 34. Химерный ген по п.33, дополнительно содержащий сигнальную последовательность, действенным образом сцепленную с молекулой ДНК, причем сигнальная последовательность обладает способностью направлять протеин, кодируемый молекулой ДНК, в хлоропласт. 34. The chimeric gene according to claim 33, further comprising a signal sequence effectively linked to the DNA molecule, the signal sequence having the ability to direct the protein encoded by the DNA molecule into the chloroplast. 35. Химерный ген по п.33, дополнительно содержащий сигнальную последовательность, действенным образом сцепленную с молекулой ДНК, причем сигнальная последовательность обладает способностью направлять протеин, кодируемый молекулой ДНК, в митохондрии. 35. The chimeric gene of Claim 33, further comprising a signal sequence effectively linked to the DNA molecule, the signal sequence having the ability to direct the protein encoded by the DNA molecule into the mitochondria. 36. Химерный ген по любому из пп.29 - 35, который представляет собой часть генома растения. 36. Chimeric gene according to any one of paragraphs.29 to 35, which is a part of the plant genome. 37. Рекомбинантный вектор, содержащий химерный ген по любому из пп.29 - 35, где этот вектор обладает способностью к стабильной трансформации в клетке-хозяине. 37. Recombinant vector containing the chimeric gene according to any one of paragraphs.29 to 35, where this vector has the ability to stable transformation in the cell host. 38. Рекомбинантный вектор, содержащий химерный ген по п.33, где этот вектор обладает способностью к стабильной трансформации в растительной клетке. 38. A recombinant vector containing the chimeric gene of Claim 33, where this vector has the capacity for stable transformation in a plant cell. 39. Клетка-хозяин, стабильно трансформированная вектором по любому из п. 37 или 38, где клетка-хозяин обладает способностью экспрессировать молекулу ДНК. 39. A host cell stably transformed with a vector according to any one of p. 37 or 38, wherein the host cell has the ability to express the DNA molecule. 40. Клетка-хозяин по п.39, выбранная из группы, состоящей из растительной клетки, бактериальной клетки, дрожжевой клетки и клетки насекомого. 40. The host cell of claim 39, selected from the group consisting of a plant cell, a bacterial cell, a yeast cell, and an insect cell. 41. Растение или растительная клетка, включая из потомство, содержащие молекулу ДНК по любому из пп.10 - 28, где молекулу ДНК экспрессируют в растении и придают соответственно растению и растительной клетке толерантность к гербициду в таких его количествах, которые ингибируют встречающуюся в естественных условиях активность протокса. 41. A plant or plant cell, including progeny, containing a DNA molecule according to any one of claims 10 to 28, where the DNA molecule is expressed in the plant and imparted to the plant and the plant cell tolerance to the herbicide in such quantities that inhibit the naturally occurring activity of the protox. 42. Растение или растительная клетка, включая их потомство, содержащие химерный ген по любому из пп.29 - 36, где химерный ген придает соответственно растению и растительной клетке толерантность к гербициду в таких его количествах, которые ингибируют встречающуюся в естественных условиях активность протокса. 42. A plant or plant cell, including its progeny, containing a chimeric gene according to any one of claims 29 to 36, where the chimeric gene imparts tolerance to the herbicide in a quantity that inhibits naturally occurring protox activity, respectively, to the plant and plant cell. 43. Растение и его потомство, в том числе его части, обладающие измененной активностью протопорфириноген-оксидазы (протокса), причем измененная активность протокса придает растению и его потомству толерантность к гербициду в таких его количествах, которые ингибируют встречающуюся в естественных условиях активность протокса. 43. The plant and its progeny, including its parts, which have an altered activity of protoporphyrinogen oxidase (protox), and the altered activity of the protox gives the herbicide tolerance to the plant and its progeny in such quantities that inhibit the protox activity that occurs naturally. 44. Растение по любому из пп.41 - 43, где растение представляет собой двудольное растение. 44. The plant according to any one of paragraphs.41 - 43, where the plant is a dicotyledonous plant. 45. Растение по п.44, где растение выбирают из группы, состоящей из сои, хлопчатника, табака, сахарной свеклы и масличного рапса. 45. The plant according to claim 44, wherein the plant is selected from the group consisting of soybean, cotton, tobacco, sugar beet and oilseed rape. 46. Растение по любому из пп.41 - 43, где растение представляет собой однодольное растение. 46. The plant according to any one of paragraphs.41 to 43, where the plant is a monocotyledonous plant. 47. Растение по п.46, где растение выбирают из группы, состоящей из кукурузы, пшеницы, сорго, ржи, овса, дернообразующих злаков и риса. 47. The plant according to claim 46, wherein the plant is selected from the group consisting of maize, wheat, sorghum, rye, oats, turf grasses and rice. 48. Растение по любому из пп.41 - 43, где измененная активность протокса обусловлена сверхэкспрессией фермента протокса, который встречается в естественных условиях в этом растении. 48. The plant according to any one of claims 41 to 43, wherein the altered activity of the protox is due to the overexpression of the protox enzyme, which occurs naturally in this plant. 49. Растение по любому из пп.41 - 43, где измененная активность протокса обусловлена экспрессией молекулы ДНК, кодирующей толерантный к гербициду фермент протокс. 49. The plant according to any one of claims 41 to 43, wherein the altered activity of the protox is due to the expression of the DNA molecule encoding the herbicide-tolerant enzyme protox. 50. Растение по п. 49, где толерантный к гербициду фермент протокс встречается в естественных условиях в прокариоте. 50. A plant according to claim 49, wherein the herbicide-tolerant enzyme protox occurs naturally in prokaryote. 51. Растение по п.50, где прокариот выбирают из группы, состоящей из E. coli, B. subtilis и S. typhimurium. 51. The plant according to claim 50, wherein the prokaryotes are selected from the group consisting of E. coli, B. subtilis and S. typhimurium. 52. Растение по п. 49, где толерантный к гербициду фермент протокс представляет собой модифицированную форму протеина, который встречается в естественных условиях в прокариоте. 52. The plant of claim 49, wherein the herbicide-tolerant protox enzyme is a modified form of protein that is naturally found in prokaryote. 53. Семенной материал растения по любому из пп.41 - 52. 53. The seed of the plant according to any one of paragraphs 41 - 52. 54. Растение по любому из пп.41 - 52, представляющее собой гибридное растение. 54. The plant according to any one of paragraphs.41 - 52, which is a hybrid plant. 55. Материал для размножения растений по любому из пп.41 - 54, снабженный защитным покрытием. 55. Plant breeding material according to any one of paragraphs.41 to 54, provided with a protective coating. 56. Материал для размножения растения по п.55, содержащий препарат, выбранный из группы, состоящей из гербицидов, инсектицидов, фунгицидов, бактериоцидов, нематоцидов, моллюскицидов или их смесей. 56. A plant propagation material according to claim 55, comprising a preparation selected from the group consisting of herbicides, insecticides, fungicides, bactericides, nematocides, molluscicides or mixtures thereof. 57. Материал для размножения растения по п.55 или 56, отличающийся тем, что он представляет собой семенной материал. 57. The plant propagation material according to claim 55 or 56, characterized in that it is a seed material. 58. Способ борьбы с ростом нежелательной растительности, включающий обработку популяции растения по любому из пп.41 - 54 эффективным количеством ингибирующего протокс гербицида. 58. A method of combating the growth of undesirable vegetation, including treating a plant population according to any one of claims 41 to 54, with an effective amount of an inhibiting protox herbicide. 59. Способ по п.58, где растение выбирают из группы, состоящей из сои, хлопчатника, табака, сахарной свеклы, масличного рапса, кукурузы, пшеницы, сорго, ржи, овса, дернообразующих злаков и риса. 59. The method of claim 58, wherein the plant is selected from the group consisting of soybean, cotton, tobacco, sugar beet, oilseed rape, corn, wheat, sorghum, rye, oats, turf grass and rice. 60. Способ по п.59, где ингибирующий протокс гербицид выбирают из группы, состоящей из арилурацила, дифенилового эфира, оксидиазола, имида, фенилпиразола, производного пиридина, 3-замещенного-2-арил-4,5,6,7-тетрагидроиндазола, фенопилата и О-фенилпирролидино- и пиперидинкарбаматного аналогов фенопилата. 60. The method of claim 59, wherein the protox-inhibiting herbicide is selected from the group consisting of aryluracil, diphenyl ether, oxydiazole, imide, phenylpyrazole, pyridine derivative, 3-substituted-2-aryl-4,5,6,7-tetrahydroindazole, phenopylate and O-phenylpyrrolidino- and piperidinecarbamate analogues of phenopylate. 61. Способ по п.60, где ингибирующий протокс гербицид представляет собой имид формулы
Figure 00000001

где Q обозначает
Figure 00000002

Figure 00000003

Figure 00000004

Figure 00000005

Figure 00000006

Figure 00000007

R1 обозначает H, Cl или F;
R2 обозначает Cl;
R3 обозначает необязательно замещенный простой эфир, тиоэфир, сложный эфир, амино- или алкильную группу,
R2 и R3 вместе могут образовывать 5- или 6-членное гетероциклическое кольцо.61. The method according to claim 60, wherein the protox-inhibiting herbicide is an imide of the formula
Figure 00000001

where Q denotes
Figure 00000002

Figure 00000003

Figure 00000004

Figure 00000005

Figure 00000006

Figure 00000007

R 1 is H, Cl or F;
R 2 denotes Cl;
R 3 denotes an optionally substituted ether, thioether, ester, amino or alkyl group,
R 2 and R 3 together can form a 5 or 6 membered heterocyclic ring. 62. Способ по п.61, где имид выбирают из группы, состоящей из
Figure 00000008

Figure 00000009

Figure 00000010

Figure 00000011

Figure 00000012

Figure 00000013

Figure 00000014

Figure 00000015

где R обозначает (C2 - C6алкенилокси)карбонил-C1 - C4алкил.62. The method of claim 61, wherein the imide is selected from the group consisting of
Figure 00000008

Figure 00000009

Figure 00000010

Figure 00000011

Figure 00000012

Figure 00000013

Figure 00000014

Figure 00000015

where R denotes (C 2 - C 6 alkenyloxy) carbonyl-C 1 - C 4 alkyl. 63. Способ по п. 58, где ингибирующий протокс гербицид имеет формулу, выбранную из группы, состоящей из
Figure 00000016

Figure 00000017

Figure 00000018

Figure 00000019

64. Способ тестирования химического соединения на его способность ингибировать активность фермента протокса из растения, включающий (а) объединение фермента протокса и протопорфириногена IX в первой реакционной смеси в условиях, при которых фермент протокс обладает способностью катализировать превращение протопорфириногена IX в протопорфирин IX; (б) объединение химического соединения, фермента протокса и протопорфириногена IX во второй реакционной смеси в таких же условиях, как и для первой реакционной смеси; (в) возбуждение первой и второй реакционных смесей волнами длиной от приблизительно 395 до приблизительно 410 нм; (г) сравнение флуоресценции первой и второй реакционных смесей при длинах волн от приблизительно 622 до приблизительно 635 нм; причем химическое соединение обладает способностью ингибировать активность фермента протокса, если флуоресценция второй реакционной смеси существенно меньше, чем флуоресценция первой реакционной смеси.63. The method according to p. 58, where the inhibiting protox herbicide has a formula selected from the group consisting of
Figure 00000016

Figure 00000017

Figure 00000018

Figure 00000019

64. A method of testing a chemical compound for its ability to inhibit the activity of the protox enzyme from a plant, including (a) combining the protox enzyme and protoporphyrinogen IX in the first reaction mixture under conditions where the protox enzyme has the ability to catalyze the conversion of protoporphyrinogen IX to protoporphyrin IX; (b) combining the chemical compound, the enzyme protox and protoporphyrinogen IX in the second reaction mixture under the same conditions as for the first reaction mixture; (c) the excitation of the first and second reaction mixtures by waves from about 395 to about 410 nm long; (d) comparing the fluorescence of the first and second reaction mixtures at wavelengths from about 622 to about 635 nm; moreover, the chemical compound has the ability to inhibit the activity of the protox enzyme, if the fluorescence of the second reaction mixture is substantially less than the fluorescence of the first reaction mixture. 65. Способ идентификации модифицированного фермента протокса, устойчивого к ингибитору протокса, присутствующего в популяции клеток, включающий стадии: (а) культивирование популяции в присутствии ингибитора протокса в количествах, которые ингибируют немодифицированную форму фермента протокса; (б) отбор клеток, полученных на стадии (а), рост которых не был ингибирован; и (в) выделение и идентификацию фермента протокса, присутствующего в клетках, отобранных на стадии (б). 65. A method for identifying a modified protox enzyme resistant to a protox inhibitor present in a cell population, comprising the steps of: (a) cultivating a population in the presence of a protox inhibitor in amounts that inhibit the unmodified form of the protox enzyme; (b) selection of cells obtained in stage (a), whose growth has not been inhibited; and (c) isolating and identifying the protox enzyme present in the cells selected in step (b). 66. Способ отбора растений, растительной ткани или растительных клеток, трансформированных представляющим интерес трансгеном, из нетрансформированных растений, включающий стадии: (а) трансформацию растения, растительной ткани или растительной клетки представляющим интерес трансгеном, обладающими способностью экспрессироваться растением, и геном, кодирующим измененный протокс, устойчивый к ингибитору протокса; (б) перенос трансформированных таким образом растений или растительных клеток в питательную среду, содержащую ингибитор протокса; и (в) отбор растений или растительных клеток, которые выжили в питательной среде. 66. A method of selecting plants, plant tissue or plant cells transformed by a transgene of interest from non-transformed plants, comprising the steps of: (a) transforming a plant, plant tissue or plant cell of a transgene of interest, capable of expressing the plant, and a gene encoding an altered protox resistant to the protox inhibitor; (b) transfer of the plant or plant cells thus transformed to the nutrient medium containing the protox inhibitor; and (c) selecting plants or plant cells that survive in the nutrient medium. 67. Зонд, способный к специфической гибридизации с геном эукариотической протопорфириноген-оксидазы или с мРНК, где этот зонд включает часть, прилегающую к кодирующей последовательности протопорфириноген-оксидазы эукариота длиной по крайней мере 10 нуклеотидов. 67. A probe capable of specific hybridization with the gene of the eukaryotic protoporphyrinogen oxidase or with mRNA, where this probe includes a portion adjacent to the coding sequence of the protoporphyrinogen oxidase of eukaryote with a length of at least 10 nucleotides. 68. Зонд по п.67, где кодирующую последовательность выбирают из группы, состоящей из последовательностей SEQ ID NO: 1, 3, 5, 7 и 9. 68. The probe according to claim 67, where the coding sequence is selected from the group consisting of SEQ ID NO: 1, 3, 5, 7 and 9. 69. Способ получения клетки-хозяина, содержащей выделенную молекулу ДНК, кодирующую протеин из эукариота, обладающий активностью протопорфириноген-оксидазы (протокса), включающий трансформацию клетки-хозяина рекомбинантной молекулой вектора по п.37 или 38. 69. A method for producing a host cell containing an isolated DNA molecule encoding a protein from eukaryote, having protoporphyrinogen oxidase (protox) activity, including transforming the host cell with a recombinant vector molecule according to claim 37 or 38. 70. Способ получения растительной клетки, содержащей выделенную молекулу ДНК, кодирующую протеин из эукариота, обладающий активностью протопорфириноген-оксидазы (протокса), включающий трансформацию растительной клетки рекомбинатной молекулой вектора по п.37 или 38. 70. A method for producing a plant cell containing an isolated DNA molecule encoding a protein from eukaryote, which has protoporphyrinogen oxidase (protox) activity, including the transformation of a plant cell with a recombinant vector molecule according to claim 37 or 38. 71. Способ получения трансгенного потомства трансгенного родительского растения, содержащего выделенную молекулу ДНК, кодирующую протеин из эукариота, обладающий активностью протопорфириноген-оксидазы (протокса), включающий трансформацию родительского растения рекомбинантной молекулой вектора по п. 37 или 38 и передачу признака толерантности к гербициду потомству трансгенного родительского растения с использованием известных методов селекции растений. 71. A method for producing transgenic progeny of a transgenic parent plant containing an isolated DNA molecule encoding a protein from eukaryote, having protoporphyrinogen oxidase (protox) activity, including the transformation of the parent plant to a recombinant vector molecule according to claim 37 or 38 and transmitting the sign of herbicide tolerance to transgene parent plant using known plant breeding methods. 72. Способ получения молекулы ДНК, кодирующей протеин из эукариота, обладающий активностью протопорфириноген-оксидазы (протокса), включающий (а) создание библиотеки кДНК из пригодного эукариотического источника; (б) идентификацию клонов кДНК, кодирующих фермент протокс, на основе их способности поддерживать ферментативную активность протокса в мутантном организме-хозяине с дефицитом этой активности. 72. A method for producing a DNA molecule encoding a protein from eukaryote, having the activity of protoporphyrinogen oxidase (protox), including (a) creating a cDNA library from a suitable eukaryotic source; (b) identification of cDNA clones encoding the protox enzyme, based on their ability to maintain the enzymatic activity of protox in a mutant host organism with a deficiency of this activity. 73. Способ получения молекулы ДНК, кодирующей протеин из эукариота, обладающий активностью протопорфириноген-оксидазы (протокса), включающий (а) создание библиотеки геномной или кДНК из пригодного эукариотического источника; (б) зондирование библиотеки молекулой-зондом по п.67. 73. A method for producing a DNA molecule encoding a protein from eukaryote, having the activity of protoporphyrinogen oxidase (protox), including (a) creating a genomic or cDNA library from a suitable eukaryotic source; (b) probing the library with the probe molecule according to claim 67. 74. Применение молекулы ДНК по любому из п.28 или 36 для придания толерантности к гербициду в таких его количествах, которые ингибируют встречающуюся в естественных условиях активность протокса из родительского растения, его потомству, включающее, во-первых, стабильную трансформацию родительского растения молекулой ДНК по любому из пп.10 - 27 путем стабильного включения молекулы ДНК в растительный геном родительского растения и, во-вторых, передачу признака толерантности к гербициду потомству трансгенного родительского растения с использованием известных методов селекции растений. 74. The use of the DNA molecule according to any one of p. 28 or 36 for imparting tolerance to the herbicide in such quantities that inhibit naturally occurring activity of protox from the parent plant, its progeny, including, first, the stable transformation of the parent plant by the DNA molecule According to any of paragraphs.10-27, by stably incorporating the DNA molecule into the plant genome of the parent plant and, secondly, transferring the sign of tolerance to the herbicide to the offspring of the transgenic parent plant using Niemi known plant breeding techniques. 75. Применение молекулы ДНК по любому из п.28 или 36 для получения медицинского препарата для лечения дефицитов активности протопорфириноген-оксидазы (протокса) у животных, в частности у людей. 75. The use of the DNA molecule according to any one of p. 28 or 36 for obtaining a medical preparation for treating deficiencies in the activity of protoporphyrinogen oxidase (protox) in animals, in particular in humans. 76. Применение молекулы ДНК по любому из п.28 или 36 для получения медицинского препарата для диагностики дефицитов активности протопорфириноген-оксидазы (протокса) у животных, в частности у людей. 76. The use of the DNA molecule according to any one of p. 28 or 36 for obtaining a medical preparation for diagnosing deficiencies in the activity of protoporphyrinogen oxidase (protox) in animals, in particular in humans. 77. Фармацевтическая композиция, содержащая наряду с фармацевтически приемлемым носителем протеин, получаемый из эукариота и обладающий активностью протопорфириноген-оксидазы (протокса), для применения в способе лечения организма животного или человека или для диагностических целей. 77. A pharmaceutical composition containing, along with a pharmaceutically acceptable carrier, a protein derived from eukaryote and having the activity of protoporphyrinogen oxidase (protox) for use in a method of treating an animal or human body or for diagnostic purposes.
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Families Citing this family (428)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6808904B2 (en) * 1994-06-16 2004-10-26 Syngenta Participations Ag Herbicide-tolerant protox genes produced by DNA shuffling
US6023012A (en) * 1996-02-28 2000-02-08 Novartis Finance Corporation DNA molecules encoding plant protoporphyrinogen oxidase
US5767373A (en) * 1994-06-16 1998-06-16 Novartis Finance Corporation Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms
US5939602A (en) * 1995-06-06 1999-08-17 Novartis Finance Corporation DNA molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof
US6084155A (en) 1995-06-06 2000-07-04 Novartis Ag Herbicide-tolerant protoporphyrinogen oxidase ("protox") genes
DE19524623A1 (en) * 1995-07-06 1997-01-09 Basf Ag 5-pyrazolylbenzoic acid derivatives
WO1997004088A1 (en) * 1995-07-20 1997-02-06 Sumitomo Chemical Company, Ltd. Porphyrin-accumulating type herbicide resistance gene
KR970021314A (en) * 1995-10-11 1997-05-28 김선중 Manufacturing method of herbicide adipose plant
DE19542520A1 (en) * 1995-11-15 1997-05-22 Basf Ag Substituted 1-methyl-3-phenylpyrazole
HUP9901044A3 (en) * 1996-02-28 2001-11-28 Syngenta Participations Ag Dna molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof
CN1236394A (en) * 1996-11-07 1999-11-24 曾尼卡有限公司 Herbicide resistant plants
DE19650216A1 (en) * 1996-12-04 1998-06-10 Inst Pflanzengenetik & Kultur Process for influencing chlorophyll biosynthesis in plants
AU739948B2 (en) * 1996-12-27 2001-10-25 Duke University Methods of conferring PPO-inhibiting herbicide resistance to plants by gene manipulation
ZA98371B (en) * 1997-01-31 1999-07-16 Du Pont Genetically transformed plants demonstrating resistance to porphyrinogen biosynthesis-inhibiting herbicides.
WO1999013087A1 (en) * 1997-09-11 1999-03-18 Nihon Nohyaku Co., Ltd. Novel protoporphyrinogen oxidase tolerant to light-requiring herbicides
AU769868B2 (en) 1998-04-10 2004-02-05 Sumitomo Chemical Company, Limited A method for evaluating the ability of a compound to inhibit the protoporphyrinogen oxidase activity
JP4788011B2 (en) * 1998-04-30 2011-10-05 住友化学株式会社 Method for imparting resistance to weed control agents
US6906245B1 (en) 1998-04-30 2005-06-14 Sumitomo Chemical Company, Limited Method for producing transgenic plants resistant to weed control compounds which disrupt the porphyrin pathways of plants
AU753020B2 (en) * 1998-04-30 2002-10-03 Sumitomo Chemical Company, Limited Method for giving resistance to weed control compounds to plants
DE19836684A1 (en) 1998-08-13 2000-02-17 Hoechst Schering Agrevo Gmbh Use of a synergistic herbicidal combination including a glufosinate- or glyphosate-type, imidazolinone or protoporphyrinogen oxidase to control weeds in rice
AR023523A1 (en) * 1999-04-19 2002-09-04 Syngenta Participations Ag HERBICIDE TREATMENT FOR SEEDS
EP1621614A3 (en) * 1999-06-15 2006-02-08 Syngenta Participations AG Herbicide target genes and methods
US6294345B1 (en) 1999-07-27 2001-09-25 Syngenta Participations Ag Genes encoding proteins essential for plant growth and methods of use
AR024934A1 (en) * 1999-07-27 2002-10-30 Novartis Ag CHEMICAL GENES
CN1373811A (en) * 1999-08-13 2002-10-09 辛根塔参与股份公司 Herbicide-tolerant protoporphyrinogen oxidase
MXPA02003589A (en) * 1999-10-11 2003-07-21 Kyoungwhan Back Process for increasing crop yield or biomass using protoporphyrinogen oxidase gene.
JP4821038B2 (en) * 1999-10-29 2011-11-24 住友化学株式会社 Herbicide-tolerant plants
JP4821036B2 (en) * 1999-10-29 2011-11-24 住友化学株式会社 Herbicide-tolerant plants
WO2001038509A1 (en) * 1999-11-26 2001-05-31 Basf Plant Science Gmbh Method for the mutagenesis of nucleotide sequences from plants algae or fungi
AU2010501A (en) * 1999-12-16 2001-06-25 Syngenta Participations Ag Herbicide target genes and methods
AU2001260114A1 (en) * 2000-03-14 2001-09-24 Syngenta Participations Ag Protoporphyrinogen oxidase ("protox") genes
DE10032633A1 (en) * 2000-07-05 2002-01-17 Bayer Ag Method for finding protoporphyrinogen oxidase inhibitors
AU2001289800B2 (en) 2000-08-11 2006-08-17 Syngenta Participations Ag Methods for stable transformation of plants
DE10052454A1 (en) * 2000-10-23 2002-05-02 Angelika Weber Method and device for automatic plant selection and automatic compilation of plant groups
US6982169B2 (en) * 2001-01-15 2006-01-03 Morphotek, Inc. Chemical inhibitors of mismatch repair
EP1925672A1 (en) 2001-06-22 2008-05-28 Syngeta Participations AG Abiotic stress responsive polynucleotides and polypeptides
US20030032069A1 (en) * 2001-06-29 2003-02-13 Muraca Patrick J. Evaluating neuropshychiatric diseases using a specimen-linked database
AR037413A1 (en) * 2001-11-27 2004-11-10 Valent Biosciences Corp INTENSIFIED HERBICIDE COMPOSITION
NZ536037A (en) * 2002-03-20 2008-04-30 Simplot Co J R Refined plant transformation
US20050034188A1 (en) * 2002-03-20 2005-02-10 J. R. Simplot Company Refined plant transformation
BRPI0409816B8 (en) 2003-04-29 2022-12-06 Pioneer Hi Bred Int GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES, CONSTRUCTS COMPRISING THEM, BACTERIAL CELL, POLYPEPTIDE HAVING GAT ACTIVITY, AS WELL AS METHOD FOR PRODUCING A TRANSGENIC PLANT RESISTANT TO GLYPHOSATE AND METHODS FOR CONTROLLING WEEDS IN A FIELD CONTAINING A CROP
US6849579B2 (en) * 2003-06-25 2005-02-01 Pbi Gordon Corporation Synergistic quinclorac herbicidal compositions
AU2004298624B2 (en) 2003-12-16 2009-12-03 Pioneer Hi-Bred International, Inc. Dominant gene suppression transgenes and methods of using same
US20070169227A1 (en) 2003-12-16 2007-07-19 Pioneer Hi-Bred International Inc. Dominant Gene Suppression Transgenes and Methods of Using Same
US20060051966A1 (en) * 2004-02-26 2006-03-09 Applied Materials, Inc. In-situ chamber clean process to remove by-product deposits from chemical vapor etch chamber
US7780793B2 (en) * 2004-02-26 2010-08-24 Applied Materials, Inc. Passivation layer formation by plasma clean process to reduce native oxide growth
US20050230350A1 (en) * 2004-02-26 2005-10-20 Applied Materials, Inc. In-situ dry clean chamber for front end of line fabrication
JP4720223B2 (en) * 2004-05-18 2011-07-13 住友化学株式会社 Plants resistant to herbicidal active compounds
EA200701844A1 (en) * 2005-03-21 2008-04-28 Басф Акциенгезельшафт INSECTICIDE MIXTURES
BRPI0610371A2 (en) 2005-05-02 2010-06-15 Purdue Research Foundation processes for increasing the yield of fermentable sugars from vegetable straw
US7671254B2 (en) * 2005-08-25 2010-03-02 The Board Of Trustees Of The University Of Illinois Herbicide resistance gene, compositions and methods
US7842856B2 (en) 2005-08-25 2010-11-30 The Board Of Trustees Of The University Of Illinois Herbicide resistance gene, compositions and methods
US7989679B2 (en) * 2006-03-02 2011-08-02 Athenix Corp. Methods and compositions for improved enzyme activity in transgenic plants
US7951995B2 (en) 2006-06-28 2011-05-31 Pioneer Hi-Bred International, Inc. Soybean event 3560.4.3.5 and compositions and methods for the identification and detection thereof
NZ581473A (en) 2007-06-01 2012-02-24 Scripps Research Inst Use of genetically modified organisms to generate biomass degrading enzymes
CL2008002690A1 (en) 2007-09-11 2009-07-17 Sapphire Energy Inc Isolated vector comprising a nucleic acid encoding an enzyme that produces an isoprenoid with two phosphates and a promoter that allows expression in a chloroplast; host cell that contains it and method to produce an isoprenoid.
US8314222B2 (en) 2007-10-05 2012-11-20 Sapphire Energy, Inc. System for capturing and modifying large pieces of genomic DNA and constructing organisms with chloroplasts
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
CA2705542A1 (en) * 2007-11-13 2009-05-22 Sapphire Energy, Inc. Production of fc-fusion polypeptides in eukaryotic algae
US7947877B2 (en) * 2008-05-14 2011-05-24 Monosanto Technology LLC Plants and seeds of spring canola variety SCV328921
US7935870B2 (en) * 2008-05-14 2011-05-03 Monsanto Technology Llc Plants and seeds of spring canola variety SCV354718
US8829282B2 (en) * 2008-05-14 2014-09-09 Monsanto Technology, Llc Plants and seeds of spring canola variety SCV425044
US7964774B2 (en) * 2008-05-14 2011-06-21 Monsanto Technology Llc Plants and seeds of spring canola variety SCV384196
EP2294179B1 (en) 2008-06-27 2014-04-23 Sapphire Energy, Inc. Induction of flocculation in photosynthetic organisms
US8748695B2 (en) * 2008-07-23 2014-06-10 Pioneer Hi-Bred International, Inc. Molecular markers linked to PPO inhibitor tolerance in soybeans
US8697941B2 (en) 2008-07-23 2014-04-15 Pioneer Hi-Bred International, Inc. Molecular markers linked to PPO inhibitor tolerance in soybeans
UA115019C2 (en) 2008-09-26 2017-09-11 Басф Агрокемікал Продактс Б.В. Herbicide-resistant ahas-mutants and methods of use
US8373025B2 (en) 2009-02-09 2013-02-12 Chromatin Germplasm, Llc Herbicide resistant sorghum
US8466342B2 (en) 2009-06-09 2013-06-18 Pioneer Hi Bred International Inc Early endosperm promoter and methods of use
US8071848B2 (en) * 2009-06-17 2011-12-06 Monsanto Technology Llc Plants and seeds of spring canola variety SCV218328
PL2638803T3 (en) 2009-09-30 2017-08-31 Basf Corporation Low volatile amine salts of anionic pesticides
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
WO2011056544A1 (en) 2009-10-26 2011-05-12 Pioneer Hi-Bred International, Inc. Somatic ovule specific promoter and methods of use
GB0920891D0 (en) 2009-11-27 2010-01-13 Syngenta Participations Ag Herbicidal compositions
AR080021A1 (en) 2010-01-26 2012-03-07 Pioneer Hi Bred Int TOLERANCE TO HPPD INHIBITING HERBICIDES (HYDROPHENYL PIRUVATO DIOXYGENASE)
US8148611B2 (en) * 2010-02-26 2012-04-03 Monsanto Technology Llc Plants and seeds of spring canola variety SCV453784
US8143488B2 (en) * 2010-02-26 2012-03-27 Monsanto Technoloy LLC Plants and seeds of spring canola variety SCV470336
US8138394B2 (en) * 2010-02-26 2012-03-20 Monsanto Technology Llc Plants and seeds of spring canola variety SCV431158
NZ601784A (en) 2010-03-08 2014-08-29 Monsanto Technology Llc Polynucleotide molecules for gene regulation in plants
US8581048B2 (en) * 2010-03-09 2013-11-12 Monsanto Technology, Llc Plants and seeds of spring canola variety SCV119103
US8153865B2 (en) * 2010-03-11 2012-04-10 Monsanto Technology Llc Plants and seeds of spring canola variety SCV152154
US9324576B2 (en) 2010-05-27 2016-04-26 Applied Materials, Inc. Selective etch for silicon films
AU2015271948A1 (en) * 2010-08-03 2016-01-21 Cibus Europe B.V. Mutated protoporphyrinogen IX oxidase (PPX) genes
US20120122223A1 (en) 2010-08-03 2012-05-17 Cibus Us Llc Mutated protoporphyrinogen ix oxidase (ppx) genes
UA112969C2 (en) * 2010-08-03 2016-11-25 Сібас Юс Ллс PLANT RESISTANT TO ONE OR MORE PPH-INHIBITING HERBICIDES CONTAINING PROTOPORPHYRINOGEN IX OXIDASE (PPX) MUTANT GENE
BR112013003221A2 (en) 2010-08-13 2019-09-24 Pioneer Hi Bred Int chimeric polynucleotide, nucleic acid construct, cell, plant, plant explant, transgenic seed, chimeric polypeptide, method of directing a polypeptide of interest to a chloroplast, expression cassette, plant cell, isolated polypeptide
EP2460404A1 (en) 2010-12-01 2012-06-06 Basf Se Compositions containing identical polyamine salts of mixed anionic pesticides
CN103748227A (en) 2010-11-24 2014-04-23 先锋国际良种公司 Brassica gat event dp-073496-4 and compositions and methods for the identification and/or detection thereof
WO2012071039A1 (en) 2010-11-24 2012-05-31 Pioner Hi-Bred International, Inc. Brassica gat event dp-061061-7 and compositions and methods for the identification and/or detection thereof
CA2820706C (en) 2010-12-03 2018-05-22 Ms Technologies, Llc Optimized expression of glyphosate resistance encoding nucleic acid molecules in plant cells
TWI667347B (en) 2010-12-15 2019-08-01 瑞士商先正達合夥公司 Soybean event syht0h2 and compositions and methods for detection thereof
US11274313B2 (en) 2010-12-16 2022-03-15 BASF Agro B.V. Plants having increased tolerance to herbicides
US10283321B2 (en) 2011-01-18 2019-05-07 Applied Materials, Inc. Semiconductor processing system and methods using capacitively coupled plasma
US8771539B2 (en) 2011-02-22 2014-07-08 Applied Materials, Inc. Remotely-excited fluorine and water vapor etch
US8999856B2 (en) 2011-03-14 2015-04-07 Applied Materials, Inc. Methods for etch of sin films
US9064815B2 (en) 2011-03-14 2015-06-23 Applied Materials, Inc. Methods for etch of metal and metal-oxide films
US8648230B2 (en) 2011-03-18 2014-02-11 Ms Technologies, Llc Regulatory regions preferentially expressing in non-pollen plant tissue
US8513487B2 (en) 2011-04-07 2013-08-20 Zenon LISIECZKO Plants and seeds of spring canola variety ND-662c
US8513494B2 (en) 2011-04-08 2013-08-20 Chunren Wu Plants and seeds of spring canola variety SCV695971
EA201301217A1 (en) 2011-05-02 2014-04-30 Басф Се THE METHOD OF ENHANCING THE ACTION OF PESTICIDE BY MEANS OF GUANIDINES
US8507761B2 (en) 2011-05-05 2013-08-13 Teresa Huskowska Plants and seeds of spring canola variety SCV372145
US8513495B2 (en) 2011-05-10 2013-08-20 Dale Burns Plants and seeds of spring canola variety SCV291489
GB201109239D0 (en) 2011-06-01 2011-07-13 Syngenta Participations Ag Herbicidal compositions
EP2713717A1 (en) 2011-06-01 2014-04-09 Basf Se Method of preparing an aqueous tank mix comprising a base
US9303270B2 (en) 2011-07-22 2016-04-05 Ricetec Aktiengesellschaft Rice resistant to HPPD and accase inhibiting herbicides
KR20140068008A (en) 2011-07-22 2014-06-05 리체텍 악티엔게젤샤프트 Methods and compositions to produce rice resistant to accase inhibitors
US8771536B2 (en) 2011-08-01 2014-07-08 Applied Materials, Inc. Dry-etch for silicon-and-carbon-containing films
AU2012292315B2 (en) 2011-08-02 2015-11-26 Basf Se Aqueous composition comprising a pesticide and a base selected from an alkali salt of hy-drogencarbonate
US8785729B2 (en) 2011-08-09 2014-07-22 Nunhems, B.V. Lettuce variety redglace
US8679982B2 (en) 2011-08-26 2014-03-25 Applied Materials, Inc. Selective suppression of dry-etch rate of materials containing both silicon and oxygen
US8679983B2 (en) 2011-09-01 2014-03-25 Applied Materials, Inc. Selective suppression of dry-etch rate of materials containing both silicon and nitrogen
US8754293B2 (en) 2011-09-09 2014-06-17 Nunhems B.V. Lettuce variety intred
EP3296402B1 (en) 2011-09-13 2020-04-15 Monsanto Technology LLC Methods and compositions for weed control
EP3434780A1 (en) 2011-09-13 2019-01-30 Monsanto Technology LLC Methods and compositions for weed control
MX350775B (en) 2011-09-13 2017-09-15 Monsanto Technology Llc Methods and compositions for weed control.
UA116089C2 (en) 2011-09-13 2018-02-12 Монсанто Текнолоджи Ллс Methods and compositios for weed control
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
WO2013040005A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
US20130326731A1 (en) 2011-09-13 2013-12-05 Daniel Ader Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
AU2012308753B2 (en) 2011-09-13 2018-05-17 Monsanto Technology Llc Methods and compositions for weed control
UA116090C2 (en) 2011-09-13 2018-02-12 Монсанто Текнолоджи Ллс Methods and compositions for weed control
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
US8927390B2 (en) 2011-09-26 2015-01-06 Applied Materials, Inc. Intrench profile
US8808563B2 (en) 2011-10-07 2014-08-19 Applied Materials, Inc. Selective etch of silicon by way of metastable hydrogen termination
WO2013070436A1 (en) 2011-11-08 2013-05-16 Applied Materials, Inc. Methods of reducing substrate dislocation during gapfill processing
US9204603B2 (en) 2011-12-21 2015-12-08 The Curators Of The University Of Missouri Soybean variety S05-11482
US20130167262A1 (en) 2011-12-21 2013-06-27 The Curators Of The University Of Missouri Soybean variety s05-11268
US9380756B2 (en) 2012-01-04 2016-07-05 Nunhems B.V. Lettuce variety multigreen 50
WO2013103365A1 (en) 2012-01-06 2013-07-11 Pioneer Hi-Bred International, Inc. Pollen preferred promoters and methods of use
EP2800816A1 (en) 2012-01-06 2014-11-12 Pioneer Hi-Bred International Inc. Ovule specific promoter and methods of use
US9499831B2 (en) 2012-01-17 2016-11-22 Pioneer Hi-Bred International, Inc. Plant transcription factors, promoters and uses thereof
WO2013116782A1 (en) 2012-02-01 2013-08-08 Dow Agrosciences Llc Novel class of glyphosate resistance genes
WO2013134651A1 (en) 2012-03-09 2013-09-12 Board Of Trustees Of Michigan State University Method of enhancing plant drought tolerance by expression of ndr1
WO2013138309A1 (en) 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
EP2825551A1 (en) 2012-03-13 2015-01-21 Pioneer Hi-Bred International Inc. Genetic reduction of male fertility in plants
EA026531B1 (en) 2012-03-21 2017-04-28 Басф Се Solid particulate tank mix adjuvant comprising a base selected from a carbonate and/or a phosphate
MX2014011298A (en) 2012-03-21 2015-05-11 Basf Se Liquid or particulate tank mix adjuvant comprising a base selected from a mixture of carbonate and hydrogencarbonate.
US20150051078A1 (en) 2012-03-21 2015-02-19 Basf Se Glyphosate tank mix adjuvant comprising a base selected from a carbonate and/or a phosphate
UY34690A (en) 2012-03-21 2013-09-30 Basf Se TANK MIXING ASSISTANT THAT INCLUDES AN ALKYL POLYGLUCIDE AND A BASE
US8859857B2 (en) 2012-04-26 2014-10-14 Monsanto Technology Llc Plants and seeds of spring canola variety SCV259778
US8835720B2 (en) 2012-04-26 2014-09-16 Monsanto Technology Llc Plants and seeds of spring canola variety SCV967592
US8878009B2 (en) 2012-04-26 2014-11-04 Monsanto Technology, LLP Plants and seeds of spring canola variety SCV318181
US8802935B2 (en) 2012-04-26 2014-08-12 Monsanto Technology Llc Plants and seeds of spring canola variety SCV942568
CN102747013B (en) * 2012-05-22 2014-10-15 中国农业科学院烟草研究所 Tobacco-black-shank-resisting and tobacco-bacterial-wilt-resisting bio-control strain Trb3
CN104619843B (en) 2012-05-24 2020-03-06 A.B.种子有限公司 Compositions and methods for silencing gene expression
WO2013188291A2 (en) 2012-06-15 2013-12-19 E. I. Du Pont De Nemours And Company Methods and compositions involving als variants with native substrate preference
AR091489A1 (en) 2012-06-19 2015-02-11 Basf Se PLANTS THAT HAVE A GREATER TOLERANCE TO HERBICIDES INHIBITORS OF PROTOPORFIRINOGENO OXIDASA (PPO)
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
US9451767B2 (en) 2012-06-21 2016-09-27 Basf Se Aqueous composition comprising dicamba and a drift control agent
AU2013285521B2 (en) 2012-07-03 2016-11-03 Basf Se Highly concentrated aqueous formulation comprising an anionic pesticide and a base
WO2014009175A1 (en) 2012-07-09 2014-01-16 Basf Se Drift control agent comprising polypropylene glycol and a triblock polymer
US9267739B2 (en) 2012-07-18 2016-02-23 Applied Materials, Inc. Pedestal with multi-zone temperature control and multiple purge capabilities
US9373517B2 (en) 2012-08-02 2016-06-21 Applied Materials, Inc. Semiconductor processing with DC assisted RF power for improved control
US9034770B2 (en) 2012-09-17 2015-05-19 Applied Materials, Inc. Differential silicon oxide etch
US9023734B2 (en) 2012-09-18 2015-05-05 Applied Materials, Inc. Radical-component oxide etch
US9390937B2 (en) 2012-09-20 2016-07-12 Applied Materials, Inc. Silicon-carbon-nitride selective etch
US9132436B2 (en) 2012-09-21 2015-09-15 Applied Materials, Inc. Chemical control features in wafer process equipment
US20140109259A1 (en) 2012-10-11 2014-04-17 Pioneer Hi Bred International Inc Guard Cell Promoters and Uses Thereof
CA2888264A1 (en) 2012-10-18 2014-04-24 Monsanto Technology Llc Methods and compositions for plant pest control
US8765574B2 (en) 2012-11-09 2014-07-01 Applied Materials, Inc. Dry etch process
US8969212B2 (en) 2012-11-20 2015-03-03 Applied Materials, Inc. Dry-etch selectivity
US9064816B2 (en) 2012-11-30 2015-06-23 Applied Materials, Inc. Dry-etch for selective oxidation removal
US8980763B2 (en) 2012-11-30 2015-03-17 Applied Materials, Inc. Dry-etch for selective tungsten removal
US20140173781A1 (en) 2012-12-13 2014-06-19 Pioneer Hi-Bred International, Inc. Methods and compositions for producing and selecting transgenic wheat plants
US9111877B2 (en) 2012-12-18 2015-08-18 Applied Materials, Inc. Non-local plasma oxide etch
BR112015015055A2 (en) 2012-12-21 2017-10-03 Pioneer Hi Bred Int METHOD FOR DETOXIFYING AN AUXIN ANALOG HERBICIDE, METHOD FOR CONTROLLING AT LEAST ONE WEED IN A GROWING AREA, METHOD FOR TESTING A PLANT RESPONSE TO ONE OR MORE COMPOUNDS
US8921234B2 (en) 2012-12-21 2014-12-30 Applied Materials, Inc. Selective titanium nitride etching
EP2941488B1 (en) 2013-01-01 2023-03-22 Monsanto Technology LLC Methods of introducing dsrna to plant seeds for modulating gene expression
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
US10256079B2 (en) 2013-02-08 2019-04-09 Applied Materials, Inc. Semiconductor processing systems having multiple plasma configurations
US9362130B2 (en) 2013-03-01 2016-06-07 Applied Materials, Inc. Enhanced etching processes using remote plasma sources
US9040422B2 (en) 2013-03-05 2015-05-26 Applied Materials, Inc. Selective titanium nitride removal
US8801952B1 (en) 2013-03-07 2014-08-12 Applied Materials, Inc. Conformal oxide dry etch
US10170282B2 (en) 2013-03-08 2019-01-01 Applied Materials, Inc. Insulated semiconductor faceplate designs
AU2014241045B2 (en) 2013-03-13 2017-08-31 Pioneer Hi-Bred International, Inc. Glyphosate application for weed control in brassica
AU2014248958A1 (en) 2013-03-13 2015-10-01 Monsanto Technology Llc Methods and compositions for weed control
AU2014249015B2 (en) 2013-03-13 2020-04-16 Monsanto Technology Llc Methods and compositions for weed control
CN105339380A (en) 2013-03-14 2016-02-17 先锋国际良种公司 Compositions and methods to control insect pests
US20140304857A1 (en) 2013-03-14 2014-10-09 Pioneer Hi Bred International Inc Maize stress related transcription factor 18 and uses thereof
CA2905595A1 (en) 2013-03-14 2014-09-25 Pioneer Hi-Bred International, Inc. Compositions having dicamba decarboxylase activity and methods of use
CA2904537A1 (en) 2013-03-14 2014-09-25 Pioneer Hi-Bred International, Inc. Compositions having dicamba decarboxylase activity and methods of use
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
CA2901316A1 (en) 2013-03-15 2014-09-25 Pioneer Hi-Bred International, Inc. Phi-4 polypeptides and methods for their use
BR112015023700A2 (en) 2013-03-15 2017-07-18 Pioneer Hi Bred Int abiotic stress tolerance enhancement method in an agricultural crop plant, transgenic corn plant, plant cell, seed, method of down regulation of an endogenous acc oxidase gene in a corn plant.
US20140271097A1 (en) 2013-03-15 2014-09-18 Applied Materials, Inc. Processing systems and methods for halide scavenging
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
US8895449B1 (en) 2013-05-16 2014-11-25 Applied Materials, Inc. Delicate dry clean
US9114438B2 (en) 2013-05-21 2015-08-25 Applied Materials, Inc. Copper residue chamber clean
US9493879B2 (en) 2013-07-12 2016-11-15 Applied Materials, Inc. Selective sputtering for pattern transfer
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015010026A2 (en) 2013-07-19 2015-01-22 Monsanto Technology Llc Compositions and methods for controlling leptinotarsa
CA2918909A1 (en) 2013-07-25 2015-01-29 Pioneer Hi-Bred International, Inc. Method for producing hybrid brassica seed
WO2015022636A2 (en) 2013-08-12 2015-02-19 Basf Se Plants having increased tolerance to herbicides
AU2014307664A1 (en) 2013-08-12 2016-02-18 BASF Agro B.V. Plants having increased tolerance to herbicides (PPO)
CA2920339C (en) 2013-08-16 2023-10-24 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US9773648B2 (en) 2013-08-30 2017-09-26 Applied Materials, Inc. Dual discharge modes operation for remote plasma
BR122020001770B1 (en) 2013-09-13 2022-11-29 Pioneer Hi-Bred International, Inc DNA CONSTRUCTION, METHOD FOR OBTAINING A TRANSGENIC PLANT, FUSION PROTEIN, METHOD FOR CONTROLLING AN INSECT PEST POPULATION, METHOD FOR INHIBITING THE GROWTH OR KILLING AN INSECT PEST
US8956980B1 (en) 2013-09-16 2015-02-17 Applied Materials, Inc. Selective etch of silicon nitride
CA2927180A1 (en) 2013-10-18 2015-04-23 Pioneer Hi-Bred International, Inc. Glyphosate-n-acetyltransferase (glyat) sequences and methods of use
US20150113681A1 (en) * 2013-10-23 2015-04-23 Syngenta Participations Ag Composition and method for enhancing plant transformation
US20160272997A1 (en) 2013-10-25 2016-09-22 Pioneer Hi-Bred International, Inc. Stem canker tolerant soybeans and methods of use
US8951429B1 (en) 2013-10-29 2015-02-10 Applied Materials, Inc. Tungsten oxide processing
US9576809B2 (en) 2013-11-04 2017-02-21 Applied Materials, Inc. Etch suppression with germanium
BR102014027442B1 (en) 2013-11-04 2022-09-27 Dow Agrosciences Llc RECOMBINANT NUCLEIC ACID MOLECULE, USE OF A CORN PLANT, PART OF A CORN PLANT OR CORN PLANT CELL COMPRISING THE SAME AND METHOD TO PRODUCE A TRANSGENIC PLANT CELL COMPRISING A DNA OF INTEREST
UY35812A (en) 2013-11-04 2015-05-29 Dow Agrosciences Llc ? OPTIMUM CORN LOCI ?.
CA2929533C (en) 2013-11-04 2023-06-06 Monsanto Technology Llc Compositions and methods for controlling arthropod parasite and pest infestations
US9236265B2 (en) 2013-11-04 2016-01-12 Applied Materials, Inc. Silicon germanium processing
EP3066202B1 (en) 2013-11-04 2021-03-03 Dow AgroSciences LLC Optimal soybean loci
US9520303B2 (en) 2013-11-12 2016-12-13 Applied Materials, Inc. Aluminum selective etch
US9245762B2 (en) 2013-12-02 2016-01-26 Applied Materials, Inc. Procedure for etch rate consistency
US9117855B2 (en) 2013-12-04 2015-08-25 Applied Materials, Inc. Polarity control for remote plasma
UA119253C2 (en) 2013-12-10 2019-05-27 Біолоджикс, Інк. Compositions and methods for virus control in varroa mite and bees
US9287095B2 (en) 2013-12-17 2016-03-15 Applied Materials, Inc. Semiconductor system assemblies and methods of operation
US9263278B2 (en) 2013-12-17 2016-02-16 Applied Materials, Inc. Dopant etch selectivity control
US9190293B2 (en) 2013-12-18 2015-11-17 Applied Materials, Inc. Even tungsten etch for high aspect ratio trenches
CN106029890B (en) 2013-12-18 2022-04-12 巴斯夫农业公司 Plants with enhanced tolerance to herbicides
TW201527312A (en) 2013-12-31 2015-07-16 Dow Agrosciences Llc Novel maize ubiquitin promoters
TW201527313A (en) 2013-12-31 2015-07-16 Dow Agrosciences Llc Novel maize ubiquitin promoters
TW201527316A (en) 2013-12-31 2015-07-16 Dow Agrosciences Llc Novel maize ubiquitin promoters
TW201527314A (en) 2013-12-31 2015-07-16 Dow Agrosciences Llc Novel maize ubiquitin promoters
AU2015206585A1 (en) 2014-01-15 2016-07-21 Monsanto Technology Llc Methods and compositions for weed control using EPSPS polynucleotides
US9287134B2 (en) 2014-01-17 2016-03-15 Applied Materials, Inc. Titanium oxide etch
US9293568B2 (en) 2014-01-27 2016-03-22 Applied Materials, Inc. Method of fin patterning
US9396989B2 (en) 2014-01-27 2016-07-19 Applied Materials, Inc. Air gaps between copper lines
US9385028B2 (en) 2014-02-03 2016-07-05 Applied Materials, Inc. Air gap process
UA120608C2 (en) 2014-02-07 2020-01-10 Піонір Хай-Бред Інтернешнл, Інк. Insecticidal proteins and methods for their use
CN106232620B (en) 2014-02-07 2022-05-13 先锋国际良种公司 Insecticidal proteins and methods of use thereof
TW201538518A (en) 2014-02-28 2015-10-16 Dow Agrosciences Llc Root specific expression conferred by chimeric gene regulatory elements
US9499898B2 (en) 2014-03-03 2016-11-22 Applied Materials, Inc. Layered thin film heater and method of fabrication
US9299575B2 (en) 2014-03-17 2016-03-29 Applied Materials, Inc. Gas-phase tungsten etch
US9299538B2 (en) 2014-03-20 2016-03-29 Applied Materials, Inc. Radial waveguide systems and methods for post-match control of microwaves
US9299537B2 (en) 2014-03-20 2016-03-29 Applied Materials, Inc. Radial waveguide systems and methods for post-match control of microwaves
US9136273B1 (en) 2014-03-21 2015-09-15 Applied Materials, Inc. Flash gate air gap
US9903020B2 (en) 2014-03-31 2018-02-27 Applied Materials, Inc. Generation of compact alumina passivation layers on aluminum plasma equipment components
BR112016022711A2 (en) 2014-04-01 2017-10-31 Monsanto Technology Llc compositions and methods for insect pest control
US9269590B2 (en) 2014-04-07 2016-02-23 Applied Materials, Inc. Spacer formation
US9309598B2 (en) 2014-05-28 2016-04-12 Applied Materials, Inc. Oxide and metal removal
US9847289B2 (en) 2014-05-30 2017-12-19 Applied Materials, Inc. Protective via cap for improved interconnect performance
US9378969B2 (en) 2014-06-19 2016-06-28 Applied Materials, Inc. Low temperature gas-phase carbon removal
US9406523B2 (en) 2014-06-19 2016-08-02 Applied Materials, Inc. Highly selective doped oxide removal method
CA2953347A1 (en) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions and methods for regulating gene expression via rna interference
EP3161138A4 (en) 2014-06-25 2017-12-06 Monsanto Technology LLC Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
EP3569067A3 (en) 2014-06-26 2020-01-22 BASF Agrochemical Products B.V. Seed treatment with acetolactate synthase (als) inhibitors
US9425058B2 (en) 2014-07-24 2016-08-23 Applied Materials, Inc. Simplified litho-etch-litho-etch process
EP3174982A4 (en) 2014-07-29 2018-06-20 Monsanto Technology LLC Compositions and methods for controlling insect pests
US9496167B2 (en) 2014-07-31 2016-11-15 Applied Materials, Inc. Integrated bit-line airgap formation and gate stack post clean
US9378978B2 (en) 2014-07-31 2016-06-28 Applied Materials, Inc. Integrated oxide recess and floating gate fin trimming
US9159606B1 (en) 2014-07-31 2015-10-13 Applied Materials, Inc. Metal air gap
US9165786B1 (en) 2014-08-05 2015-10-20 Applied Materials, Inc. Integrated oxide and nitride recess for better channel contact in 3D architectures
US9659753B2 (en) 2014-08-07 2017-05-23 Applied Materials, Inc. Grooved insulator to reduce leakage current
WO2016022516A1 (en) 2014-08-08 2016-02-11 Pioneer Hi-Bred International, Inc. Ubiquitin promoters and introns and methods of use
US9553102B2 (en) 2014-08-19 2017-01-24 Applied Materials, Inc. Tungsten separation
US9355856B2 (en) 2014-09-12 2016-05-31 Applied Materials, Inc. V trench dry etch
US20170247719A1 (en) 2014-09-17 2017-08-31 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US9355862B2 (en) 2014-09-24 2016-05-31 Applied Materials, Inc. Fluorine-based hardmask removal
US9368364B2 (en) 2014-09-24 2016-06-14 Applied Materials, Inc. Silicon etch process with tunable selectivity to SiO2 and other materials
US9613822B2 (en) 2014-09-25 2017-04-04 Applied Materials, Inc. Oxide etch selectivity enhancement
US9355922B2 (en) 2014-10-14 2016-05-31 Applied Materials, Inc. Systems and methods for internal surface conditioning in plasma processing equipment
US9966240B2 (en) 2014-10-14 2018-05-08 Applied Materials, Inc. Systems and methods for internal surface conditioning assessment in plasma processing equipment
US10435706B2 (en) 2014-10-16 2019-10-08 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
BR112017009437B1 (en) 2014-11-07 2021-11-16 Basf Se METHOD FOR PREPARING A TANK MIXTURE, PESTICIDE FORMULATION, PHYTOPATHOGENIC FUNGI CONTROL METHOD AND TANK MIX ADJUVANT USE
US11637002B2 (en) 2014-11-26 2023-04-25 Applied Materials, Inc. Methods and systems to enhance process uniformity
US9299583B1 (en) 2014-12-05 2016-03-29 Applied Materials, Inc. Aluminum oxide selective etch
US10224210B2 (en) 2014-12-09 2019-03-05 Applied Materials, Inc. Plasma processing system with direct outlet toroidal plasma source
US10573496B2 (en) 2014-12-09 2020-02-25 Applied Materials, Inc. Direct outlet toroidal plasma source
US20170359965A1 (en) 2014-12-19 2017-12-21 E I Du Pont De Nemours And Company Polylactic acid compositions with accelerated degradation rate and increased heat stability
US9502258B2 (en) 2014-12-23 2016-11-22 Applied Materials, Inc. Anisotropic gap etch
EP3240889A4 (en) 2014-12-31 2018-06-20 Synthetic Genomics, Inc. Compositions and methods for high efficiency in vivo genome editing
US9343272B1 (en) 2015-01-08 2016-05-17 Applied Materials, Inc. Self-aligned process
US11257693B2 (en) 2015-01-09 2022-02-22 Applied Materials, Inc. Methods and systems to improve pedestal temperature control
US9373522B1 (en) 2015-01-22 2016-06-21 Applied Mateials, Inc. Titanium nitride removal
MX2017009521A (en) 2015-01-22 2018-11-09 Monsanto Technology Llc Compositions and methods for controlling leptinotarsa.
US9449846B2 (en) 2015-01-28 2016-09-20 Applied Materials, Inc. Vertical gate separation
US9728437B2 (en) 2015-02-03 2017-08-08 Applied Materials, Inc. High temperature chuck for plasma processing systems
US20160225652A1 (en) 2015-02-03 2016-08-04 Applied Materials, Inc. Low temperature chuck for plasma processing systems
US9881805B2 (en) 2015-03-02 2018-01-30 Applied Materials, Inc. Silicon selective removal
RU2017144238A (en) 2015-05-19 2019-06-19 Пайонир Хай-Бред Интернэшнл, Инк. INSECTICIDAL PROTEINS AND METHODS OF THEIR APPLICATION
CN107750125A (en) 2015-06-02 2018-03-02 孟山都技术有限公司 For by the composition and method in delivery of polynucleotides to plant
AU2016270913A1 (en) 2015-06-03 2018-01-04 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
EP3310803A1 (en) 2015-06-16 2018-04-25 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
WO2017023778A1 (en) * 2015-08-03 2017-02-09 Monsanto Technology Llc Methods and compositions for herbicide tolerance in plants
CN116003550A (en) 2015-08-06 2023-04-25 先锋国际良种公司 Insecticidal proteins of plant origin and methods of use thereof
US9691645B2 (en) 2015-08-06 2017-06-27 Applied Materials, Inc. Bolted wafer chuck thermal management systems and methods for wafer processing systems
US9741593B2 (en) 2015-08-06 2017-08-22 Applied Materials, Inc. Thermal management systems and methods for wafer processing systems
US9349605B1 (en) 2015-08-07 2016-05-24 Applied Materials, Inc. Oxide etch selectivity systems and methods
US10504700B2 (en) 2015-08-27 2019-12-10 Applied Materials, Inc. Plasma etching systems and methods with secondary plasma injection
US10378023B2 (en) 2015-09-01 2019-08-13 Monsanto Technology Llc Methods and compositions for herbicide tolerance in plants
EP3390431A1 (en) 2015-12-18 2018-10-24 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CA3004056C (en) 2015-12-22 2024-01-23 Pioneer Hi-Bred International, Inc. Tissue-preferred promoters and methods of use
US11096344B2 (en) 2016-02-05 2021-08-24 Pioneer Hi-Bred International, Inc. Genetic loci associated with brown stem rot resistance in soybean and methods of use
EA201892293A1 (en) 2016-05-04 2019-04-30 Пайонир Хай-Бред Интернэшнл, Инк. INSECTICIDAL PROTEINS AND METHODS OF THEIR APPLICATION
US10522371B2 (en) 2016-05-19 2019-12-31 Applied Materials, Inc. Systems and methods for improved semiconductor etching and component protection
US10504754B2 (en) 2016-05-19 2019-12-10 Applied Materials, Inc. Systems and methods for improved semiconductor etching and component protection
UA127983C2 (en) 2016-05-20 2024-03-06 Басф Агро Б.В. Dual transit peptides for targeting polypeptides
CA3022858A1 (en) 2016-06-16 2017-12-21 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CN109661458B (en) 2016-06-16 2023-05-09 纽希得营养澳大利亚私人有限公司 Inbred transgenic rape line NS-B50027-4 and seeds thereof
CN109689847B (en) 2016-06-16 2023-08-11 纽希得营养澳大利亚私人有限公司 Excellent seed rape NS-B50027-4
EP3475430B1 (en) 2016-06-24 2022-06-01 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
US20190359992A1 (en) 2016-06-28 2019-11-28 Cellectis Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
US9865484B1 (en) 2016-06-29 2018-01-09 Applied Materials, Inc. Selective etch using material modification and RF pulsing
EP3478052B1 (en) 2016-07-01 2021-08-25 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
WO2018013333A1 (en) 2016-07-12 2018-01-18 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CN109790153A (en) 2016-07-27 2019-05-21 巴斯夫农业公司 Plant with increased herbicide tolerant
RU2763534C2 (en) * 2016-07-29 2021-12-30 Монсанто Текнолоджи Ллс Methods and compositions for gene expression in plants
EP3494224B1 (en) 2016-08-05 2022-03-30 Ricetec, Inc. Methods and compositions for combinations of mutations associated with herbicide resistance/tolerance in rice
US10629473B2 (en) 2016-09-09 2020-04-21 Applied Materials, Inc. Footing removal for nitride spacer
US10062575B2 (en) 2016-09-09 2018-08-28 Applied Materials, Inc. Poly directional etch by oxidation
US9934942B1 (en) 2016-10-04 2018-04-03 Applied Materials, Inc. Chamber with flow-through source
US9721789B1 (en) 2016-10-04 2017-08-01 Applied Materials, Inc. Saving ion-damaged spacers
US10546729B2 (en) 2016-10-04 2020-01-28 Applied Materials, Inc. Dual-channel showerhead with improved profile
US10062585B2 (en) 2016-10-04 2018-08-28 Applied Materials, Inc. Oxygen compatible plasma source
US10062579B2 (en) 2016-10-07 2018-08-28 Applied Materials, Inc. Selective SiN lateral recess
US9947549B1 (en) 2016-10-10 2018-04-17 Applied Materials, Inc. Cobalt-containing material removal
BR112019008800A2 (en) 2016-11-01 2019-07-16 Pioneer Hi Bred Int insecticidal polypeptide, insecticidal composition, recombinant polynucleotide, dna construct, plant cell or transgenic plant, method for inhibiting growth or exterminating an agricultural insect pest population, method for inhibiting growth or exterminating an insect pest, method for controlling lepidoptera and / or coleoptera insect infestation in a transgenic plant and provide insect resistance management and use of at least one insecticide polypeptide
US9768034B1 (en) 2016-11-11 2017-09-19 Applied Materials, Inc. Removal methods for high aspect ratio structures
US10163696B2 (en) 2016-11-11 2018-12-25 Applied Materials, Inc. Selective cobalt removal for bottom up gapfill
US10242908B2 (en) 2016-11-14 2019-03-26 Applied Materials, Inc. Airgap formation with damage-free copper
US10026621B2 (en) 2016-11-14 2018-07-17 Applied Materials, Inc. SiN spacer profile patterning
MX2019007469A (en) 2016-12-20 2020-02-07 Basf Agro Bv Plants having increased tolerance to herbicides.
US10566206B2 (en) 2016-12-27 2020-02-18 Applied Materials, Inc. Systems and methods for anisotropic material breakthrough
US10431429B2 (en) 2017-02-03 2019-10-01 Applied Materials, Inc. Systems and methods for radial and azimuthal control of plasma uniformity
US10403507B2 (en) 2017-02-03 2019-09-03 Applied Materials, Inc. Shaped etch profile with oxidation
US10043684B1 (en) 2017-02-06 2018-08-07 Applied Materials, Inc. Self-limiting atomic thermal etching systems and methods
US10319739B2 (en) 2017-02-08 2019-06-11 Applied Materials, Inc. Accommodating imperfectly aligned memory holes
US10943834B2 (en) 2017-03-13 2021-03-09 Applied Materials, Inc. Replacement contact process
US10319649B2 (en) 2017-04-11 2019-06-11 Applied Materials, Inc. Optical emission spectroscopy (OES) for remote plasma monitoring
US11109591B2 (en) 2017-04-24 2021-09-07 Taminco Bvba Single phase liquids of alkanolamine salts of dicamba
US11276590B2 (en) 2017-05-17 2022-03-15 Applied Materials, Inc. Multi-zone semiconductor substrate supports
US11276559B2 (en) 2017-05-17 2022-03-15 Applied Materials, Inc. Semiconductor processing chamber for multiple precursor flow
US10497579B2 (en) 2017-05-31 2019-12-03 Applied Materials, Inc. Water-free etching methods
US10049891B1 (en) 2017-05-31 2018-08-14 Applied Materials, Inc. Selective in situ cobalt residue removal
US10920320B2 (en) 2017-06-16 2021-02-16 Applied Materials, Inc. Plasma health determination in semiconductor substrate processing reactors
US10541246B2 (en) 2017-06-26 2020-01-21 Applied Materials, Inc. 3D flash memory cells which discourage cross-cell electrical tunneling
US10727080B2 (en) 2017-07-07 2020-07-28 Applied Materials, Inc. Tantalum-containing material removal
US10541184B2 (en) 2017-07-11 2020-01-21 Applied Materials, Inc. Optical emission spectroscopic techniques for monitoring etching
US10354889B2 (en) 2017-07-17 2019-07-16 Applied Materials, Inc. Non-halogen etching of silicon-containing materials
US10170336B1 (en) 2017-08-04 2019-01-01 Applied Materials, Inc. Methods for anisotropic control of selective silicon removal
US10043674B1 (en) 2017-08-04 2018-08-07 Applied Materials, Inc. Germanium etching systems and methods
US10297458B2 (en) 2017-08-07 2019-05-21 Applied Materials, Inc. Process window widening using coated parts in plasma etch processes
CN111373046A (en) 2017-09-25 2020-07-03 先锋国际良种公司 Tissue-preferred promoters and methods of use
US10283324B1 (en) 2017-10-24 2019-05-07 Applied Materials, Inc. Oxygen treatment for nitride etching
US10128086B1 (en) 2017-10-24 2018-11-13 Applied Materials, Inc. Silicon pretreatment for nitride removal
CA3082869A1 (en) 2017-11-29 2019-06-06 Basf Se Plants having increased tolerance to herbicides
US10256112B1 (en) 2017-12-08 2019-04-09 Applied Materials, Inc. Selective tungsten removal
CA3026528A1 (en) 2017-12-15 2019-06-15 Monsanto Technology Llc Methods and compositions for ppo herbicide tolerance
US10903054B2 (en) 2017-12-19 2021-01-26 Applied Materials, Inc. Multi-zone gas distribution systems and methods
US11328909B2 (en) 2017-12-22 2022-05-10 Applied Materials, Inc. Chamber conditioning and removal processes
US10854426B2 (en) 2018-01-08 2020-12-01 Applied Materials, Inc. Metal recess for semiconductor structures
US10964512B2 (en) 2018-02-15 2021-03-30 Applied Materials, Inc. Semiconductor processing chamber multistage mixing apparatus and methods
US10679870B2 (en) 2018-02-15 2020-06-09 Applied Materials, Inc. Semiconductor processing chamber multistage mixing apparatus
TWI766433B (en) 2018-02-28 2022-06-01 美商應用材料股份有限公司 Systems and methods to form airgaps
US10593560B2 (en) 2018-03-01 2020-03-17 Applied Materials, Inc. Magnetic induction plasma source for semiconductor processes and equipment
US10319600B1 (en) 2018-03-12 2019-06-11 Applied Materials, Inc. Thermal silicon etch
US10497573B2 (en) 2018-03-13 2019-12-03 Applied Materials, Inc. Selective atomic layer etching of semiconductor materials
US10573527B2 (en) 2018-04-06 2020-02-25 Applied Materials, Inc. Gas-phase selective etching systems and methods
US10490406B2 (en) 2018-04-10 2019-11-26 Appled Materials, Inc. Systems and methods for material breakthrough
US10699879B2 (en) 2018-04-17 2020-06-30 Applied Materials, Inc. Two piece electrode assembly with gap for plasma control
US10886137B2 (en) 2018-04-30 2021-01-05 Applied Materials, Inc. Selective nitride removal
US11702668B2 (en) 2018-05-22 2023-07-18 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
EP3833747A1 (en) 2018-06-28 2021-06-16 Pioneer Hi-Bred International, Inc. Methods for selecting transformed plants
US10755941B2 (en) 2018-07-06 2020-08-25 Applied Materials, Inc. Self-limiting selective etching systems and methods
US10872778B2 (en) 2018-07-06 2020-12-22 Applied Materials, Inc. Systems and methods utilizing solid-phase etchants
US10672642B2 (en) 2018-07-24 2020-06-02 Applied Materials, Inc. Systems and methods for pedestal configuration
US10892198B2 (en) 2018-09-14 2021-01-12 Applied Materials, Inc. Systems and methods for improved performance in semiconductor processing
US11049755B2 (en) 2018-09-14 2021-06-29 Applied Materials, Inc. Semiconductor substrate supports with embedded RF shield
US11062887B2 (en) 2018-09-17 2021-07-13 Applied Materials, Inc. High temperature RF heater pedestals
US11417534B2 (en) 2018-09-21 2022-08-16 Applied Materials, Inc. Selective material removal
US11682560B2 (en) 2018-10-11 2023-06-20 Applied Materials, Inc. Systems and methods for hafnium-containing film removal
US11121002B2 (en) 2018-10-24 2021-09-14 Applied Materials, Inc. Systems and methods for etching metals and metal derivatives
US11641800B2 (en) 2020-02-06 2023-05-09 Deere & Company Agricultural harvesting machine with pre-emergence weed detection and mitigation system
US11240961B2 (en) 2018-10-26 2022-02-08 Deere & Company Controlling a harvesting machine based on a geo-spatial representation indicating where the harvesting machine is likely to reach capacity
US11672203B2 (en) 2018-10-26 2023-06-13 Deere & Company Predictive map generation and control
US11178818B2 (en) 2018-10-26 2021-11-23 Deere & Company Harvesting machine control system with fill level processing based on yield data
US11079725B2 (en) 2019-04-10 2021-08-03 Deere & Company Machine control using real-time model
US11467605B2 (en) 2019-04-10 2022-10-11 Deere & Company Zonal machine control
US11589509B2 (en) 2018-10-26 2023-02-28 Deere & Company Predictive machine characteristic map generation and control system
US11653588B2 (en) 2018-10-26 2023-05-23 Deere & Company Yield map generation and control system
US11957072B2 (en) 2020-02-06 2024-04-16 Deere & Company Pre-emergence weed detection and mitigation system
CA3111090A1 (en) 2018-10-31 2020-05-07 Pioneer Hi-Bred International, Inc. Compositions and methods for ochrobactrum-mediated plant transformation
US11437242B2 (en) 2018-11-27 2022-09-06 Applied Materials, Inc. Selective removal of silicon-containing materials
US11721527B2 (en) 2019-01-07 2023-08-08 Applied Materials, Inc. Processing chamber mixing systems
US10920319B2 (en) 2019-01-11 2021-02-16 Applied Materials, Inc. Ceramic showerheads with conductive electrodes
US11234366B2 (en) 2019-04-10 2022-02-01 Deere & Company Image selection for machine control
US11778945B2 (en) 2019-04-10 2023-10-10 Deere & Company Machine control using real-time model
CN114340391A (en) 2019-09-03 2022-04-12 巴斯夫欧洲公司 Polymers for spray drift control of pesticide sprays
WO2021094132A1 (en) 2019-11-15 2021-05-20 Basf Corporation Methods of using a composition comprising an anionic pesticide and a buffer
US11477940B2 (en) 2020-03-26 2022-10-25 Deere & Company Mobile work machine control based on zone parameter modification
CN111423990B (en) * 2020-04-10 2021-08-27 科稷达隆(北京)生物技术有限公司 Oxyfluorfen sensitive saccharomycete and preparation method thereof
AU2021290887A1 (en) 2020-06-15 2023-01-19 Basf Se A stable, solvent-free, self-emulsifiable concentrate
CA3186978A1 (en) 2020-07-14 2022-01-20 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2022047022A1 (en) 2020-08-26 2022-03-03 Vindara, Inc. METHOD and/or COMPOSITIONS FOR LETTUCE (LACTUCA SATIVA) BREEDING and/or VARIETIES DEVELOPED THEREBY
US11849671B2 (en) 2020-10-09 2023-12-26 Deere & Company Crop state map generation and control system
US11825768B2 (en) 2020-10-09 2023-11-28 Deere & Company Machine control using a predictive map
US11849672B2 (en) 2020-10-09 2023-12-26 Deere & Company Machine control using a predictive map
US11895948B2 (en) 2020-10-09 2024-02-13 Deere & Company Predictive map generation and control based on soil properties
US11675354B2 (en) 2020-10-09 2023-06-13 Deere & Company Machine control using a predictive map
US11871697B2 (en) 2020-10-09 2024-01-16 Deere & Company Crop moisture map generation and control system
US11474523B2 (en) 2020-10-09 2022-10-18 Deere & Company Machine control using a predictive speed map
US11946747B2 (en) 2020-10-09 2024-04-02 Deere & Company Crop constituent map generation and control system
US11727680B2 (en) 2020-10-09 2023-08-15 Deere & Company Predictive map generation based on seeding characteristics and control
US11844311B2 (en) 2020-10-09 2023-12-19 Deere & Company Machine control using a predictive map
US11711995B2 (en) 2020-10-09 2023-08-01 Deere & Company Machine control using a predictive map
US11592822B2 (en) 2020-10-09 2023-02-28 Deere & Company Machine control using a predictive map
US11635765B2 (en) 2020-10-09 2023-04-25 Deere & Company Crop state map generation and control system
US11889788B2 (en) 2020-10-09 2024-02-06 Deere & Company Predictive biomass map generation and control
US11927459B2 (en) 2020-10-09 2024-03-12 Deere & Company Machine control using a predictive map
US11864483B2 (en) 2020-10-09 2024-01-09 Deere & Company Predictive map generation and control system
US11874669B2 (en) 2020-10-09 2024-01-16 Deere & Company Map generation and control system
US11650587B2 (en) 2020-10-09 2023-05-16 Deere & Company Predictive power map generation and control system
US11845449B2 (en) 2020-10-09 2023-12-19 Deere & Company Map generation and control system
US11889787B2 (en) 2020-10-09 2024-02-06 Deere & Company Predictive speed map generation and control system
WO2022112072A1 (en) 2020-11-24 2022-06-02 Syngenta Crop Protection Ag Herbicidal compounds
EP4317425A1 (en) * 2021-04-02 2024-02-07 Qingdao KingAgroot Chemical Compound Co., Ltd. Ppo polypeptide having tolerance to ppo inhibitor herbicide, and application
AU2022253338A1 (en) 2021-04-07 2023-10-12 Syngenta Crop Protection Ag Herbicidal compounds
AU2022306931A1 (en) 2021-07-09 2023-12-07 Syngenta Crop Protection Ag Herbicidal compositions
WO2023280697A1 (en) 2021-07-09 2023-01-12 Syngenta Crop Protection Ag Herbicidal compositions
CN117545355A (en) 2021-07-09 2024-02-09 先正达农作物保护股份公司 Herbicidal composition
PE20240596A1 (en) 2021-07-09 2024-03-21 Syngenta Crop Protection Ag HERBICIDAL COMPOSITIONS
CN117897378A (en) 2021-09-03 2024-04-16 巴斯夫农业种子解决方案美国有限责任公司 Plants with increased tolerance to herbicides
AR127152A1 (en) 2021-09-27 2023-12-20 BASF Agricultural Solutions Seed US LLC NON-GMO SUNFLOWER PLANTS THAT HAVE INCREASED TOLERANCE TO HERBICIDES
WO2023169984A1 (en) 2022-03-11 2023-09-14 Syngenta Crop Protection Ag Herbicidal compounds
WO2023222589A1 (en) 2022-05-20 2023-11-23 Syngenta Crop Protection Ag Herbicidal compounds
WO2024012968A1 (en) 2022-07-13 2024-01-18 Syngenta Crop Protection Ag Herbicidal pyrimidinone derivatives
WO2024020360A1 (en) 2022-07-18 2024-01-25 Pairwise Plants Services, Inc. Mustard green plants named 'pwrg-1', 'pwrg-2,' and 'pwsgc'

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI891054A (en) 1988-03-08 1989-09-09 Ciba Geigy Ag KEMISKT REGLERBARA DNA SEQUENCER AND GENER SAMT OLIKA ANVAENDNINGAR DAERAV.
EP0360750A3 (en) * 1988-09-22 1991-01-02 Ciba-Geigy Ag Novel herbicide tolerant plants
US5693507A (en) 1988-09-26 1997-12-02 Auburn University Genetic engineering of plant chloroplasts
CN1039283C (en) * 1988-12-12 1998-07-29 Fmc公司 Prodn. and use of porphyrins
NZ231658A (en) * 1988-12-12 1992-05-26 Fmc Corp Inhibitors of protoporphyrinogen oxidase and compositions for killing tumour cells
IL97645A (en) 1990-03-23 1997-03-18 Gist Brocades Nv Production of enzymes in seeds and their use
GB9009307D0 (en) 1990-04-25 1990-06-20 Ici Plc Dna,constructs,cells and plant derived therefrom
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
IL98405A0 (en) * 1990-06-11 1992-07-15 Fmc Corp Pharmaceutical compositions containing enzyme inhibiting agents
DK162790D0 (en) 1990-07-06 1990-07-06 Novo Nordisk As PLANT CELL
IE913215A1 (en) 1990-09-13 1992-02-25 Gist Brocades Nv Transgenic plants having a modified carbohydrate content
US5290926A (en) * 1990-09-14 1994-03-01 Ciba-Geigy Corporation Isolated DNA Encoding plant histidinol dehydrogenase
ATE271131T1 (en) * 1991-05-09 2004-07-15 Univ Arizona TRANSGENIC PLANTS WITH MODIFIED POLYOL CONTENT
US5409823A (en) 1992-09-24 1995-04-25 Ciba-Geigy Corporation Methods for the production of hybrid seed
US5693506A (en) 1993-11-16 1997-12-02 The Regents Of The University Of California Process for protein production in plants
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
GB9401780D0 (en) 1994-01-31 1994-03-23 Nickerson Biocem Ltd Modified plants
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5530191A (en) 1994-03-24 1996-06-25 Rutgers, The State University Of New Jersey Method for producing cytoplasmic male sterility in plants and use thereof in production of hybrid seed
US5939602A (en) * 1995-06-06 1999-08-17 Novartis Finance Corporation DNA molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof
US6023012A (en) * 1996-02-28 2000-02-08 Novartis Finance Corporation DNA molecules encoding plant protoporphyrinogen oxidase
US5767373A (en) * 1994-06-16 1998-06-16 Novartis Finance Corporation Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms
US5608144A (en) 1994-08-12 1997-03-04 Dna Plant Technology Corp. Plant group 2 promoters and uses thereof
US6020312A (en) * 1994-09-13 2000-02-01 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US6084155A (en) * 1995-06-06 2000-07-04 Novartis Ag Herbicide-tolerant protoporphyrinogen oxidase ("protox") genes
WO1997004088A1 (en) 1995-07-20 1997-02-06 Sumitomo Chemical Company, Ltd. Porphyrin-accumulating type herbicide resistance gene
GEP20012558B (en) 1995-08-10 2001-10-25 Rutgers Univ Nuclear-Encoded Transcription System in Plastids of Higher Plants
HUP9901044A3 (en) 1996-02-28 2001-11-28 Syngenta Participations Ag Dna molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof
BR9707948A (en) 1996-03-06 1999-07-27 Univ Rutgers Process for obtaining transplastomic plants

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