RU96122298A - Arylaliphatic amine amides of benzoic acid (substituted with benzoic acid), cyclohexane- and 1-adamantanecarboxylic acids, possessing anti-arrhythmic, local anesthetic and analgesic - Google Patents

Arylaliphatic amine amides of benzoic acid (substituted with benzoic acid), cyclohexane- and 1-adamantanecarboxylic acids, possessing anti-arrhythmic, local anesthetic and analgesic

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Publication number
RU96122298A
RU96122298A RU96122298/04A RU96122298A RU96122298A RU 96122298 A RU96122298 A RU 96122298A RU 96122298/04 A RU96122298/04 A RU 96122298/04A RU 96122298 A RU96122298 A RU 96122298A RU 96122298 A RU96122298 A RU 96122298A
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RU
Russia
Prior art keywords
benzoic acid
cyclohexane
substituted
analgesic
arrhythmic
Prior art date
Application number
RU96122298/04A
Other languages
Russian (ru)
Other versions
RU2130922C1 (en
Inventor
Борисова Е.Я
Е.В. Арзамасцев
П.В. Головков
И.А. Елисеева
А.Г. Бельтюкова
О.А. Терехова
М.И. Черкашин
Г.А. Толстиков
Original Assignee
Московская государственная академия тонкой химической технологии им.М.В.Ломоносова
Filing date
Publication date
Application filed by Московская государственная академия тонкой химической технологии им.М.В.Ломоносова filed Critical Московская государственная академия тонкой химической технологии им.М.В.Ломоносова
Priority to RU96122298A priority Critical patent/RU2130922C1/en
Priority claimed from RU96122298A external-priority patent/RU2130922C1/en
Publication of RU96122298A publication Critical patent/RU96122298A/en
Application granted granted Critical
Publication of RU2130922C1 publication Critical patent/RU2130922C1/en

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Claims (1)

Арилалифатические аминоамиды бензойной (замещенной бензойной), циклогексан- и 1-адамантанкарбоновых кислот общей формулы
Figure 00000001

причем когда
R = C6H5, то R1 = NC4H8O, а n = 4, или n = 6, или n = 7; R1 = NC5H10, а n = 5; R1 = NC6H12, а n = 6; R1 = N(C4H9)2, а n = 7;
R = C6H4Br-п, то R1 = N(C2H5)2, а n = 4, или n = 6, или n = 7; R1 = NC5H10, а n = 6, n = 7; R1 = NC4H8O, а n = 7; R1 = N(C4H9)2, а n = 7;
R = C6H4Cl-п, то R1 = N(CH3)2, а n = 4; R1 = NC4H8O, а n = 4; R1 = NC5H10, а n = 7;
R = C6H4NO2-п, то R1 = N(C2H5)2, а n = 7;
R = C6H4NO2-м, то R1 = N(C2H5)2, а n = 4, или n = 7; R1 = NC4H8O, а n = 6, или n = 7; R1 = NC5H10, а n = 6;
R = C6H4CH3-п, то R1 = NC4H8O, а n = 6; R1 = NC5H10, а n = 6;
R = C6H11, то R1 = NC4H8O, а n = 6; R1 = NC5H10, а n = 6;
когда R = 1-адамантил, то R1 = NC4H8O, а n = 6,
проявляющих антиаритмическую, местноанестезирующую и анальгетическую активности.Arylaliphatic amino amides of benzoic (substituted benzoic), cyclohexane and 1-adamantanecarboxylic acids of the general formula
Figure 00000001

and when
R = C 6 H 5 , then R 1 = NC 4 H 8 O, and n = 4, or n = 6, or n = 7; R 1 = NC 5 H 10 and n = 5; R 1 = NC 6 H 12 , and n = 6; R 1 = N (C 4 H 9 ) 2 and n = 7;
R = C 6 H 4 Br-p, then R 1 = N (C 2 H 5 ) 2 , and n = 4, or n = 6, or n = 7; R 1 = NC 5 H 10 , and n = 6, n = 7; R 1 = NC 4 H 8 O, and n = 7; R 1 = N (C 4 H 9 ) 2 and n = 7;
R = C 6 H 4 Cl-p, then R 1 = N (CH 3 ) 2 , and n = 4; R 1 = NC 4 H 8 O, and n = 4; R 1 = NC 5 H 10 and n = 7;
R = C 6 H 4 NO 2 -n, then R 1 = N (C 2 H 5 ) 2 , and n = 7;
R = C 6 H 4 NO 2 , then R 1 = N (C 2 H 5 ) 2 , and n = 4, or n = 7; R 1 = NC 4 H 8 O, and n = 6, or n = 7; R 1 = NC 5 H 10 , and n = 6;
R = C 6 H 4 CH 3 -n, then R 1 = NC 4 H 8 O, and n = 6; R 1 = NC 5 H 10 , and n = 6;
R = C 6 H 11 , then R 1 = NC 4 H 8 O, and n = 6; R 1 = NC 5 H 10 , and n = 6;
when R = 1-adamantyl, then R 1 = NC 4 H 8 O, and n = 6,
exhibiting antiarrhythmic, local anesthetic and analgesic activity.
RU96122298A 1996-11-13 1996-11-13 Arylaliphatic aminoamides of benzoic (substituted benzoic), cyclohexane- and 1-adamantane carboxylic acids showing anti-arrhythmic, topical anesthetic and analgetic activity RU2130922C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU96122298A RU2130922C1 (en) 1996-11-13 1996-11-13 Arylaliphatic aminoamides of benzoic (substituted benzoic), cyclohexane- and 1-adamantane carboxylic acids showing anti-arrhythmic, topical anesthetic and analgetic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU96122298A RU2130922C1 (en) 1996-11-13 1996-11-13 Arylaliphatic aminoamides of benzoic (substituted benzoic), cyclohexane- and 1-adamantane carboxylic acids showing anti-arrhythmic, topical anesthetic and analgetic activity

Publications (2)

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RU96122298A true RU96122298A (en) 1999-01-27
RU2130922C1 RU2130922C1 (en) 1999-05-27

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2712638C1 (en) * 2019-04-02 2020-01-30 Федеральное государственное бюджетное образовательное учреждение высшего образования "МИРЭА - Российский технологический университет" (РТУ МИРЭА) N-(2-(2-(dialkylamino)ethoxy)ethyl)carboxamides and hydrochlorides thereof, having antiarrhythmic activity, and pharmaceutical compositions based thereon

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