RU96112175A - POLYCYCLIC ANTI-PARASITIC MEANS, METHOD AND STRAIN FOR THEIR PRODUCTION AND THEIR APPLICATION - Google Patents

POLYCYCLIC ANTI-PARASITIC MEANS, METHOD AND STRAIN FOR THEIR PRODUCTION AND THEIR APPLICATION

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Publication number
RU96112175A
RU96112175A RU96112175/04A RU96112175A RU96112175A RU 96112175 A RU96112175 A RU 96112175A RU 96112175/04 A RU96112175/04 A RU 96112175/04A RU 96112175 A RU96112175 A RU 96112175A RU 96112175 A RU96112175 A RU 96112175A
Authority
RU
Russia
Prior art keywords
treatment
compound according
parasitic infections
nodulisporium
strain
Prior art date
Application number
RU96112175/04A
Other languages
Russian (ru)
Other versions
RU2139874C1 (en
Inventor
В.Домбровски Анне
Г.Эндрис Ричард
Л.Хелмс Грегори
Д.Хенсенс Отто
Г.Ондейка Джон
А.Остлинд Дан
Д.Полишук Джон
Л.Цинк Дебора
Original Assignee
Мерк Энд Ко., Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/146,638 external-priority patent/US5399582A/en
Application filed by Мерк Энд Ко., Инк. filed Critical Мерк Энд Ко., Инк.
Publication of RU96112175A publication Critical patent/RU96112175A/en
Application granted granted Critical
Publication of RU2139874C1 publication Critical patent/RU2139874C1/en

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Claims (1)

1. Соединение, имеющее формулу
Figure 00000001

Figure 00000002

или
Figure 00000003

2. Способ получения соединения по п. 1, отличающийся тем, что включает ферментацию в среде источников углерода, источников азота и источников следовых количеств элементов, продуцирующего штамма MF-5954 вида Nodulisporium, и выделение соединений.1. The compound having the formula
Figure 00000001

Figure 00000002

or
Figure 00000003

2. A method of obtaining a compound according to claim 1, characterized in that it includes fermentation in the medium of carbon sources, nitrogen sources and sources of trace amounts of elements producing the MF-5954 strain of the Nodulisporium type, and the isolation of the compounds. 3. Способ по п.2, отличающийся тем, что штамм представляет собой MF-5954 вида Nodulisporium, ATCC 74245. 3. The method according to claim 2, characterized in that the strain is a MF-5954 species Nodulisporium, ATCC 74245. 4. Способ лечения паразитарных инфекций, отличающийся тем, что включает применение к живому организму, подверженному заражению эффективного количества соединения по п.1. 4. A method of treating parasitic infections, characterized in that it comprises applying to a living organism susceptible to infection an effective amount of a compound according to claim 1 5. Способ по п.4 лечения паразитарных инфекций животных, отличающийся тем, что включает лечение животного, зараженного паразитами, эффективным количеством соединения по п.1. 5. The method according to claim 4 for the treatment of parasitic infections of animals, characterized in that it includes the treatment of an animal infected with parasites, an effective amount of a compound according to claim 1. 6. Способ по п.4 лечения паразитарных инфекций растений или растительных культур, отличающийся тем, что включает обработку растения или почвы, в которой оно произрастает, эффективным количеством соединения по п.1. 6. The method according to claim 4 for the treatment of parasitic infections of plants or crops, characterized in that it includes the treatment of a plant or soil in which it grows, an effective amount of the compound according to claim 1. 7. Композиция, полезная для лечения паразитарной инфекции, отличающийся тем, что содержит инертный носитель и соединение по п.1. 7. Composition useful for the treatment of parasitic infection, characterized in that it contains an inert carrier and a compound according to claim 1. 8. Композиция по п.7, полезная для лечения паразитарных инфекций растений. 8. The composition according to claim 7, useful for the treatment of parasitic infections of plants. 9. Композиция по п. 7, полезная для лечения паразитарных инфекций животных. 9. The composition according to p. 7, useful for the treatment of parasitic infections of animals. 10. Биологически чистая культура MF-5954 вида Nodulisporium, способная к продуцированию соединения по п.1. 10. Biologically pure culture of MF-5954 Nodulisporium species capable of producing the compound according to claim 1. 11. Биологически чистая культура по п.10, отличающаяся тем, что представляет собой MF-5954 вида Nodulisporium, ATCC 74245. 11. Biologically pure culture of claim 10, characterized in that it is a MF-5954 species Nodulisporium, ATCC 74245.
RU96112175A 1993-11-01 1994-10-27 Polycyclic compounds, method and strain for their preparing, antiparasitic composition and method of supression of parasitic infections RU2139874C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US146,638 1993-11-01
US08/146,638 US5399582A (en) 1993-11-01 1993-11-01 Antiparasitic agents
PCT/US1994/012302 WO1995012599A1 (en) 1993-11-01 1994-10-27 Polycyclic antiparasitic agents, process and strain for their preparation and their use

Publications (2)

Publication Number Publication Date
RU96112175A true RU96112175A (en) 1998-09-27
RU2139874C1 RU2139874C1 (en) 1999-10-20

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US (2) US5399582A (en)
EP (1) EP0726902B1 (en)
JP (1) JP3557212B2 (en)
KR (1) KR100333017B1 (en)
CN (2) CN1046943C (en)
AT (1) ATE188476T1 (en)
AU (1) AU688405B2 (en)
CA (1) CA2174645C (en)
CZ (1) CZ286032B6 (en)
DE (1) DE69422526T2 (en)
DK (1) DK0726902T3 (en)
ES (1) ES2143558T3 (en)
FI (2) FI110871B (en)
GR (1) GR3032493T3 (en)
HU (1) HU221276B1 (en)
NO (1) NO315942B1 (en)
NZ (1) NZ275339A (en)
PL (1) PL178879B1 (en)
PT (1) PT726902E (en)
RU (1) RU2139874C1 (en)
SI (1) SI0726902T1 (en)
SK (1) SK281510B6 (en)
WO (1) WO1995012599A1 (en)
ZA (1) ZA948542B (en)

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