RU95121768A - LOCAL AROMATIC BREAKDOWN COMPOSITION FOR INTRODUCTION TO THE NOSE CAVITY AND METHOD FOR TREATING NOSE CAVITY DISEASES - Google Patents

LOCAL AROMATIC BREAKDOWN COMPOSITION FOR INTRODUCTION TO THE NOSE CAVITY AND METHOD FOR TREATING NOSE CAVITY DISEASES

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Publication number
RU95121768A
RU95121768A RU95121768/14A RU95121768A RU95121768A RU 95121768 A RU95121768 A RU 95121768A RU 95121768/14 A RU95121768/14 A RU 95121768/14A RU 95121768 A RU95121768 A RU 95121768A RU 95121768 A RU95121768 A RU 95121768A
Authority
RU
Russia
Prior art keywords
composition according
paragraphs
aromatic
local
menthoxypropane
Prior art date
Application number
RU95121768/14A
Other languages
Russian (ru)
Inventor
Вильям Флетчер Бек
Original Assignee
Зе Проктер энд Гэмбл Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зе Проктер энд Гэмбл Компани filed Critical Зе Проктер энд Гэмбл Компани
Publication of RU95121768A publication Critical patent/RU95121768A/en

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Claims (7)

1. Локальная ароматическая противоотечная композиция для введения в носовую полость, состоящая из (а) 0,001 - 1% одного или нескольких ароматических соединений, выбранных из группы, включающей 3 - 1-ментоксипропан-1,2-диол, N-замещенные п-ментан-3-карбоксамиды, ациклические карбоксамиды и их смеси, (б) 0,01 - 99,99% фармацевтически приемлемого водного раствора, предпочтительно водного солевого раствора с рН 3 - 7, в качестве носителя.1. Local aromatic decongestant composition for insertion into the nasal cavity, consisting of (a) 0.001 - 1% of one or more aromatic compounds selected from the group consisting of 3 - 1-menthoxypropane-1,2-diol, N-substituted p-menthane -3-carboxamides, acyclic carboxamides and mixtures thereof, (b) 0.01 to 99.99% of a pharmaceutically acceptable aqueous solution, preferably an aqueous saline solution with a pH of 3 to 7, as a carrier. 2. Композиция по п. 1, отличающаяся тем, что она содержит 0,001 - 0,3% ароматического соединения от веса композиции, и ароматическое соединение выбрано из группы, включающей 3 - 1-ментоксипропан-1,2-диол, N-замещенные п-ментан-3-карбоксамиды и ациклические карбоксамиды предпочтительно в отношении 2 : 1 : 1 соответственно. 2. The composition according to p. 1, characterized in that it contains 0.001 - 0.3% of the aromatic compound by weight of the composition, and the aromatic compound is selected from the group comprising 3 - 1-menthoxypropane-1,2-diol, N-substituted p methane-3-carboxamides and acyclic carboxamides, preferably in a ratio of 2: 1: 1, respectively. 3. Композиция по любому из пп. 1 - 2, отличающаяся тем, что она содержит смесь 3 - 1-ментоксипропан-1,2-диола и N-этил-п-ментан-3-карбоксамида. 3. The composition according to any one of paragraphs. 1 - 2, characterized in that it contains a mixture of 3 - 1-menthoxypropane-1,2-diol and N-ethyl-p-menthane-3-carboxamide. 4. Композиция по любому из пп. 1 - 3, отличающаяся тем, что она содержит смесь 3 - 1-ментоксипропан-1,2-диола, N-этил-п-ментан-3-карбоксамида и N, 2,3-триметил-2-изопропилбутанамида. 4. The composition according to any one of paragraphs. 1 to 3, characterized in that it contains a mixture of 3 - 1-menthoxypropane-1,2-diol, N-ethyl-p-menthane-3-carboxamide and N, 2,3-trimethyl-2-isopropylbutanamide. 5. Композиция по любому из пп. 1 - 4, отличающаяся тем, что она дополнительно содержит 0,5 - 10% поверхностно-активного вещества, предпочтительно выбранного из группы, включающей полиоксиэтиленовые производные неполных эфиров жирных кислот и ангидрида сорбита и оксиэтилированную третоктилированную фенолформальдегидную смолу. 5. The composition according to any one of paragraphs. 1 to 4, characterized in that it further comprises 0.5 to 10% of a surfactant, preferably selected from the group consisting of polyoxyethylene derivatives of partial esters of fatty acids and sorbitol anhydride and an ethoxylated tert-ethyl phenol-formaldehyde resin. 6. Композиция по любому из пп. 1 - 5, отличающаяся тем, что она содержит дополнительно 0,01 - 5% увлажняющего вещества и 0,01 - 5% терапевтически приемлемого загустителя. 6. The composition according to any one of paragraphs. 1 to 5, characterized in that it additionally contains 0.01 to 5% of a moisturizing substance and 0.01 to 5% of a therapeutically acceptable thickener. 7. Способ лечения заболеваний носовой полости, заключающийся во введении безопасного и эффективного количества локальной выделяющей ароматическое соединение противоотечной композиции по любому из предыдущих пунктов. 7. A method for treating diseases of the nasal cavity, which consists in introducing a safe and effective amount of a local aromatic compound-releasing decongestant composition according to any one of the preceding paragraphs.
RU95121768/14A 1993-04-30 1994-03-25 LOCAL AROMATIC BREAKDOWN COMPOSITION FOR INTRODUCTION TO THE NOSE CAVITY AND METHOD FOR TREATING NOSE CAVITY DISEASES RU95121768A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/056.010 1993-04-30

Publications (1)

Publication Number Publication Date
RU95121768A true RU95121768A (en) 1998-02-10

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