RU95118736A - INTERMEDIATE COMPOUND FOR OBTAINING HETEROCYCLIC COMPOUNDS WITH ANTI-DIABETIC ACTIVITY - Google Patents

INTERMEDIATE COMPOUND FOR OBTAINING HETEROCYCLIC COMPOUNDS WITH ANTI-DIABETIC ACTIVITY

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Publication number
RU95118736A
RU95118736A RU95118736/04A RU95118736A RU95118736A RU 95118736 A RU95118736 A RU 95118736A RU 95118736/04 A RU95118736/04 A RU 95118736/04A RU 95118736 A RU95118736 A RU 95118736A RU 95118736 A RU95118736 A RU 95118736A
Authority
RU
Russia
Prior art keywords
group
carbon atoms
ring
aryl
intermediate compound
Prior art date
Application number
RU95118736/04A
Other languages
Russian (ru)
Other versions
RU2151145C1 (en
Inventor
Фудзита Такаси
Фудзимото Коити
Есиока Такао
Янагисава Хироаки
Фудзивара Тосихико
Хорикоси Хироеси
Огути Минору
Вада Кунио
Original Assignee
Санкио Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санкио Компани Лимитед filed Critical Санкио Компани Лимитед
Publication of RU95118736A publication Critical patent/RU95118736A/en
Application granted granted Critical
Publication of RU2151145C1 publication Critical patent/RU2151145C1/en

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Claims (1)

1. Соединение формулы (ХIV)
Figure 00000001

где Y и Y1 - каждый независимо означает атом кислорода или атом серы;
R - атом водорода, алкильная группа, имеющая от 1 до 4 атомов углерода, алкоксигруппа, имеющая от 1 до 4 атомов углерода, атом галогена, гидроксигруппа, нитрогруппа, аралкильная группа, в которой алкильная группа, имеющая от 1 до 5 атомов углерода, замещена арильной группой, имеющей от 6 до 10 атомов углерода в кольце, или группа формулы -NRaRb
где Ra и Rb - (одинаковые или различные) каждый атом водорода, алкильная группа, имеющая от 1 до 8 атомов углерода, аралкильная группа, в которой алкильная группа, имеющая от 1 до 5 атомов углерода, замещена арильной группой, имеющей от 6 до 10 атомов углерода в кольце, арильная группа, имеющая 6 - 10 атомов углерода в кольце, алифатическая карбоксиацильная группа, имеющая от 1 до 11 атомов углерода, алифатически карбоксиацильная группа, которая имеет от 2 до 6 атомов углерода и которая замещена арильной группой, имеющей от 6 до 10 атомов углерода в кольце, или ароматическая карбоксиацильная группа, в которой арильная часть имеет от 6 до 10 атомов углерода в кольце;
m - целое число от 1 до 5;
Q - низшая алкоксикарбонильная группа, формильная группа, защищенная формильная группа, карбоксильная группа или гидроксильная группа,
и соли этого соединения.1. The compound of formula (XIV)
Figure 00000001

where Y and Y 1 - each independently means an oxygen atom or a sulfur atom;
R is a hydrogen atom, an alkyl group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms, a halogen atom, a hydroxy group, a nitro group, an aralkyl group in which an alkyl group having from 1 to 5 carbon atoms is substituted an aryl group having from 6 to 10 carbon atoms in the ring, or a group of the formula —NR a R b
where R a and R b - (identical or different) each is a hydrogen atom, an alkyl group having from 1 to 8 carbon atoms, an aralkyl group in which an alkyl group having from 1 to 5 carbon atoms is replaced by an aryl group having from 6 up to 10 carbon atoms in the ring, an aryl group having 6 to 10 carbon atoms in the ring, an aliphatic carboxyacyl group having from 1 to 11 carbon atoms, an aliphatic carboxyacyl group that has from 2 to 6 carbon atoms and which is substituted by an aryl group having from 6 to 10 carbon atoms in the ring, Whether an aromatic carboxylic acyl group in which the aryl part has from 6 to 10 ring carbon atoms;
m is an integer from 1 to 5;
Q is a lower alkoxycarbonyl group, a formyl group, a protected formyl group, a carboxyl group or a hydroxyl group,
and salts of this compound.
RU95118736/04A 1994-04-11 1995-04-10 Intermediate compound for synthesis of heterocyclic compounds showing antidiabetic activity RU2151145C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6-72083 1994-04-11
JP7208394 1994-04-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU95105423/04A Division RU2114844C1 (en) 1994-04-11 1995-04-10 Thiazolidinedione derivatives or their pharmaceutically acceptable salts, pharmaceutical composition based on thereof and a method of treatment and prophylaxis of diseases

Publications (2)

Publication Number Publication Date
RU95118736A true RU95118736A (en) 1997-09-20
RU2151145C1 RU2151145C1 (en) 2000-06-20

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Family Applications (2)

Application Number Title Priority Date Filing Date
RU95105423/04A RU2114844C1 (en) 1994-04-11 1995-04-10 Thiazolidinedione derivatives or their pharmaceutically acceptable salts, pharmaceutical composition based on thereof and a method of treatment and prophylaxis of diseases
RU95118736/04A RU2151145C1 (en) 1994-04-11 1995-04-10 Intermediate compound for synthesis of heterocyclic compounds showing antidiabetic activity

Family Applications Before (1)

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RU95105423/04A RU2114844C1 (en) 1994-04-11 1995-04-10 Thiazolidinedione derivatives or their pharmaceutically acceptable salts, pharmaceutical composition based on thereof and a method of treatment and prophylaxis of diseases

Country Status (22)

Country Link
US (6) US5624935A (en)
EP (2) EP0676398B1 (en)
KR (1) KR950032188A (en)
CN (1) CN1060173C (en)
AT (2) ATE222895T1 (en)
AU (1) AU683348B2 (en)
CA (1) CA2146701A1 (en)
CZ (1) CZ289317B6 (en)
DE (2) DE69528000T2 (en)
DK (2) DK0676398T3 (en)
ES (2) ES2180477T3 (en)
FI (1) FI951731A (en)
HK (2) HK1029338A1 (en)
HU (1) HU219887B (en)
ID (1) ID20564A (en)
IL (1) IL113313A (en)
NO (2) NO305987B1 (en)
NZ (1) NZ270917A (en)
PT (2) PT676398E (en)
RU (2) RU2114844C1 (en)
TW (2) TW503237B (en)
ZA (1) ZA952990B (en)

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