RU95117692A - Alkaline salts of orotic and amino acid amides having hypertensive activity - Google Patents

Alkaline salts of orotic and amino acid amides having hypertensive activity

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Publication number
RU95117692A
RU95117692A RU95117692/04A RU95117692A RU95117692A RU 95117692 A RU95117692 A RU 95117692A RU 95117692/04 A RU95117692/04 A RU 95117692/04A RU 95117692 A RU95117692 A RU 95117692A RU 95117692 A RU95117692 A RU 95117692A
Authority
RU
Russia
Prior art keywords
orotic
acid amides
alkaline salts
amino acid
compounds
Prior art date
Application number
RU95117692/04A
Other languages
Russian (ru)
Other versions
RU2086543C1 (en
Inventor
Ю.В. Буров
Л.Н. Сернов
В.В. Гацура
М.Г. Плешаков
В.И. Снегоцкий
Е.Н. Шамшина
Е.К. Григорьева
Original Assignee
Всероссийский научный центр по безопасности биологически активных веществ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Всероссийский научный центр по безопасности биологически активных веществ filed Critical Всероссийский научный центр по безопасности биологически активных веществ
Priority to RU95117692A priority Critical patent/RU2086543C1/en
Publication of RU95117692A publication Critical patent/RU95117692A/en
Application granted granted Critical
Publication of RU2086543C1 publication Critical patent/RU2086543C1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

FIELD: medicine. SUBSTANCE: claimed invention describes novel chemical compositions such as alkaline salts of orotic acid and amino acid amides of general formula:wherein n is 1-5; M is Na K or Li. Desired compounds are prepared by processes well known in the art. In experiments on animals said compounds show high hypertensive activity and can therefore find medical applications in the treatment of chronic hypotonic states. EFFECT: improved properties of the title orotic and aminoacid acid compounds.

Claims (1)

Представлены новые химические соединения - щелочные соли амидов оротовой кислоты и аминокислот общей формулы, приведенной в описании. Целевые соединения получают известными способами. В эксперименте на животных указанные соединения проявили высокую гипертензивную активность и в результате этого могут найти применение в медицине для лечения хронических гипотонических состояний.New chemical compounds are presented - alkaline salts of orotic acid amides and amino acids of the general formula given in the description. Target compounds are prepared by known methods. In an animal experiment, these compounds showed high hypertensive activity and, as a result, can be used in medicine for the treatment of chronic hypotonic conditions.
RU95117692A 1995-10-16 1995-10-16 Alkaline salts of amides of orotic acid and amino acids, having hypertensive action RU2086543C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95117692A RU2086543C1 (en) 1995-10-16 1995-10-16 Alkaline salts of amides of orotic acid and amino acids, having hypertensive action

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU95117692A RU2086543C1 (en) 1995-10-16 1995-10-16 Alkaline salts of amides of orotic acid and amino acids, having hypertensive action

Publications (2)

Publication Number Publication Date
RU95117692A true RU95117692A (en) 1996-11-20
RU2086543C1 RU2086543C1 (en) 1997-08-10

Family

ID=20172967

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95117692A RU2086543C1 (en) 1995-10-16 1995-10-16 Alkaline salts of amides of orotic acid and amino acids, having hypertensive action

Country Status (1)

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RU (1) RU2086543C1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236952B2 (en) 2007-12-18 2012-08-07 Northern Innovations Holding Corp. Preparations containing amino acids and orotic acid
EP2231622A4 (en) * 2007-12-18 2011-01-19 Northern Innovations And Formulations Corp Preparations containing amino acids and orotic acid

Also Published As

Publication number Publication date
RU2086543C1 (en) 1997-08-10

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