RU95109640A - Method of preparing taxol and taxanes from embryonic cultures of plants genus taxus - Google Patents

Method of preparing taxol and taxanes from embryonic cultures of plants genus taxus

Info

Publication number
RU95109640A
RU95109640A RU95109640/13A RU95109640A RU95109640A RU 95109640 A RU95109640 A RU 95109640A RU 95109640/13 A RU95109640/13 A RU 95109640/13A RU 95109640 A RU95109640 A RU 95109640A RU 95109640 A RU95109640 A RU 95109640A
Authority
RU
Russia
Prior art keywords
taxanes
tissues
preparing taxol
derivatives
taxol
Prior art date
Application number
RU95109640/13A
Other languages
Russian (ru)
Other versions
RU2120740C1 (en
Inventor
Бо-Сик Ли
Kr]
Санг-Хо Сан
Original Assignee
Форест Генетик Рисеч Инститют Форестри
Форест Генетик Рисеч Инститют Форестри, Администрейшн
Администрейшн (KR)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Форест Генетик Рисеч Инститют Форестри, Форест Генетик Рисеч Инститют Форестри, Администрейшн, Администрейшн (KR) filed Critical Форест Генетик Рисеч Инститют Форестри
Publication of RU95109640A publication Critical patent/RU95109640A/en
Application granted granted Critical
Publication of RU2120740C1 publication Critical patent/RU2120740C1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

FIELD: pharmacy. SUBSTANCE: invention proposes methods of preparing taxol and its derivatives (taxanes) by extraction of tissues of different yew species (Taxus) or cells obtained from their. Method of preparing taxol or its derivatives by tissue and/or cultural fluid extraction. The indicated tissues are zygotic embryos. Cellular cultures of zygotic embryos of different yew species were used for induction of somatic embryos or embryogenic callus. EFFECT: higher efficiency.

Claims (1)

В изобретении предложены способы получения таксола и его производных (таксанов) путем экстракции тканей различных видов тисса (Taxus) или полученных из них клеток. Способ получения таксола или его производных путем экстракции тканей и/или культурной среды характеризуется тем, что указанные ткани различных видов тисса представляют собой зиготные эмбрионы. Клеточные культуры зиготных эмбрионов различных видов тисса используют для индукции соматических эмбрионов или эмбриогенного каллуса.The invention provides methods for producing taxol and its derivatives (taxanes) by extracting tissues of various types of yew tree (Taxus) or cells derived from them. A method of obtaining taxol or its derivatives by extraction of tissues and / or culture medium is characterized in that these tissues of various types of yew are zygotic embryos. Cell cultures of zygotic embryos of various types of yew are used for the induction of somatic embryos or embryogenic callus.
RU95109640A 1993-07-06 1994-07-06 Method of producing taxol and taxones from embryo plant culture of taxus genus RU2120740C1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
KR930012641 1993-07-06
KR12641/93 1993-07-06
KR1993-12641 1993-07-06
KR1019940013914A KR950005081B1 (en) 1993-07-06 1994-06-20 Method for producing taxol and its derivatives from embryo cultures of taxus species
KR13914/94 1994-06-20
KR1994-13914 1994-06-20

Publications (2)

Publication Number Publication Date
RU95109640A true RU95109640A (en) 1997-06-10
RU2120740C1 RU2120740C1 (en) 1998-10-27

Family

ID=26629770

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95109640A RU2120740C1 (en) 1993-07-06 1994-07-06 Method of producing taxol and taxones from embryo plant culture of taxus genus

Country Status (8)

Country Link
EP (1) EP0662144A1 (en)
JP (1) JP2795542B2 (en)
KR (1) KR950005081B1 (en)
CN (1) CN1047795C (en)
AU (1) AU675147B2 (en)
CA (1) CA2143455C (en)
RU (1) RU2120740C1 (en)
WO (1) WO1995002063A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
DK0954596T3 (en) 1996-05-24 2006-05-15 Phyton Inc Increased production of taxanes by taxus cell culture
CN1055120C (en) * 1996-11-27 2000-08-02 天津大学 Method for improving content and release of yew alcohol in Taxus chinensis cell
KR100287465B1 (en) * 1997-06-25 2001-05-02 나까니시 히로유끼 Method for producing taxane type diterpenes
KR100432426B1 (en) * 2001-07-11 2004-05-22 엔프라니 주식회사 Method for preparing Taxus seed extract and Taxus seed oil, and cosmetic composition containing them
KR20030066162A (en) * 2002-02-04 2003-08-09 (주)하나이피에스 Dha jerk fish meat
AU2008202078B2 (en) * 2007-10-10 2012-05-31 Wellkey Holdings Limited Stability of secondary metabolite mass production through synchronized plant cell cultures
KR20100127727A (en) * 2009-05-26 2010-12-06 주식회사 운화 Plant stem cell derived from cambium of family salicaceae and method of isolating and culturing the same
EP2436757A2 (en) * 2009-05-26 2012-04-04 Unhwa Corporation Plant stem cell derived from cambium of family asteraceae and method for the isolated culturing thereof
WO2010137918A2 (en) * 2009-05-28 2010-12-02 주식회사 운화 Plant stem cell derived from cambium of family solanaceae, and method for isolating and culturing same
JP2012217441A (en) * 2011-04-14 2012-11-12 Housetec Inc Method for producing taxanes, and method for inducing callus
CN103923873A (en) * 2014-03-18 2014-07-16 上海交通大学 Method for reducing plant cell browning risk through absorption of quinone substances with silica gel
KR20180080487A (en) * 2017-01-04 2018-07-12 대한민국(산림청 국립산림과학원장) Method of enhancing embryogenic tissue growth by treatment of anti-browning and polyamines in Japanese larch
CN114788496B (en) * 2022-04-07 2023-07-21 江苏省中国科学院植物研究所 Method for inducing efficient embryogenesis of larch through solid-liquid alternate culture
KR102519385B1 (en) * 2022-10-07 2023-04-06 유성근 Manufacturing method of seasoned drying fillet using scallop coat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
ATE146527T1 (en) * 1991-02-12 1997-01-15 Nippon Steel Corp METHOD FOR PRODUCING TAXOL USING TAXUS SPECIES CELL CULTURE
US5344775A (en) * 1991-11-15 1994-09-06 Escagenetics Corporation Synthesis of taxanes in culture using pseudocalluscells
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species
CA2131532A1 (en) * 1992-04-01 1993-10-14 Steven R. Wann Induction of somatic embryogenesis in taxus, and the production of taxane-ring containing alkaloids therefrom
US5322779A (en) * 1992-04-16 1994-06-21 The Research And Development Institute, Inc. At Montana State University Taxol production by taxomyces andreanae
EP0642586A4 (en) * 1992-05-21 1995-11-29 Penn State Res Found CULTURED -i(TAXUS) TISSUES AS A SOURCE OF TAXOL, RELATED TAXANES AND OTHER NOVEL ANTI-TUMOR/ANTI-VIRAL COMPOUNDS.

Also Published As

Publication number Publication date
KR950002782A (en) 1995-02-16
CA2143455C (en) 1999-09-07
JP2795542B2 (en) 1998-09-10
RU2120740C1 (en) 1998-10-27
AU675147B2 (en) 1997-01-23
CN1111911A (en) 1995-11-15
WO1995002063A1 (en) 1995-01-19
AU7085994A (en) 1995-02-06
JPH08503618A (en) 1996-04-23
CN1047795C (en) 1999-12-29
CA2143455A1 (en) 1995-01-19
EP0662144A1 (en) 1995-07-12
KR950005081B1 (en) 1995-05-18

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