RU95108342A - Vaccine strain of measles virus - Google Patents
Vaccine strain of measles virusInfo
- Publication number
- RU95108342A RU95108342A RU95108342/13A RU95108342A RU95108342A RU 95108342 A RU95108342 A RU 95108342A RU 95108342/13 A RU95108342/13 A RU 95108342/13A RU 95108342 A RU95108342 A RU 95108342A RU 95108342 A RU95108342 A RU 95108342A
- Authority
- RU
- Russia
- Prior art keywords
- properties
- strain
- virulent
- guinea pigs
- tcd
- Prior art date
Links
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
FIELD: medicinal biotechnology, virology. SUBSTANCE: invention proposes the strain "Orloff-B", "ГКВ" N 2326 and describes the following strain properties: cultural-morphological characters (buoyant density is 1.18-1.20 g/$$$, titer = 4-6 lg $$$/0.5 ml and 7-8 lg $$$/0.5 ml on cells BHK-21); physiological-biochemical characters (optimum pH = 7.4, inactivation at 56 C for 30 min, sensitivity to ether and acetone); antigenic properties (hemagglutinating activity in vitro - 2-8 "ГАЕ"); immunogenic properties (100% formation of specific antibody in rabbits and guinea pigs, at reverse titer in "РТГА" - from 640-2560 to 1280-10240, respectively; serum conversion is 80-100%); virulent properties (strain does not show virulent or contagious properties); toxicity (no toxicity at dose 1000 $$$/0.5 ml in guinea pigs and mice). EFFECT: enhanced immunogenicity of vaccine against measles, improved properties of strain-producer. 3 tbl
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU95108342/13A RU2081912C1 (en) | 1995-05-22 | 1995-05-22 | Strain of measles virus "orlov-b" for vaccine preparing |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU95108342/13A RU2081912C1 (en) | 1995-05-22 | 1995-05-22 | Strain of measles virus "orlov-b" for vaccine preparing |
Publications (2)
Publication Number | Publication Date |
---|---|
RU95108342A true RU95108342A (en) | 1996-12-20 |
RU2081912C1 RU2081912C1 (en) | 1997-06-20 |
Family
ID=20168026
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU95108342/13A RU2081912C1 (en) | 1995-05-22 | 1995-05-22 | Strain of measles virus "orlov-b" for vaccine preparing |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2081912C1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2492235C1 (en) * | 2012-07-09 | 2013-09-10 | Федеральное бюджетное учреждение науки "Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера" | Rubella virus strain "orlov" (u) for obtaining medicinal immuno-biological preparations (mibp) |
RU2606848C2 (en) * | 2015-05-21 | 2017-01-10 | Федеральное бюджетное учреждение науки "Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера" (ФБУН НИИ эпидемиологии и микробиологии имени Пастера) | Method of determining biological activity of measles, epidemic parotitis and rubella during production of associated preparations (versions) |
-
1995
- 1995-05-22 RU RU95108342/13A patent/RU2081912C1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2081912C1 (en) | 1997-06-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20040523 |