RU95106890A - Method of prophylaxis of aerogenic infections caused by horse venezuelan encephalomyelitis, marburg and ebola viruses - Google Patents

Method of prophylaxis of aerogenic infections caused by horse venezuelan encephalomyelitis, marburg and ebola viruses

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Publication number
RU95106890A
RU95106890A RU95106890/13A RU95106890A RU95106890A RU 95106890 A RU95106890 A RU 95106890A RU 95106890/13 A RU95106890/13 A RU 95106890/13A RU 95106890 A RU95106890 A RU 95106890A RU 95106890 A RU95106890 A RU 95106890A
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RU
Russia
Prior art keywords
reaferon
ridostin
aerogenic
marburg
prophylaxis
Prior art date
Application number
RU95106890/13A
Other languages
Russian (ru)
Other versions
RU2105565C1 (en
Inventor
Л.А. Котляров
А.Н. Сергеев
А.Б. Рыжиков
Л.Е. Булычев
О.В. Пьянков
И.В. Плясунов
О.Г. Пьянкова
В.Д. Порываев
В.А. Петрищенко
Original Assignee
Государственный научный центр вирусологии и биотехнологии "Вектор"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Государственный научный центр вирусологии и биотехнологии "Вектор" filed Critical Государственный научный центр вирусологии и биотехнологии "Вектор"
Priority to RU95106890/13A priority Critical patent/RU2105565C1/en
Publication of RU95106890A publication Critical patent/RU95106890A/en
Application granted granted Critical
Publication of RU2105565C1 publication Critical patent/RU2105565C1/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

FIELD: medicine, virology. SUBSTANCE: method involves parenteral administration of preparations containing interferon inductor and/or immunomodulating agent before or at period of pathogen incorporation in organism by aerogenic way. These preparations were administrated by intranasal route simultaneously with parenteral administration at the same doses. Prophylaxis preparations: reaferon or ridostin, or reaferon with ridostin, or reaferon with polyribonate, or reaferon with ridostin and polyribonate that were administrated in organism twice per a day at the following total doses: reaferon (1.0-100.0) x 10IU/kg; ridostin 1.0-8.0 mg/kg, and polyribonate 10.0-100.0 mg/kg. Method is used for nonspecific immunoprophylaxis of viral infection. EFFECT: enhanced prophylaxis action. 4 tbl

Claims (1)

Изобретение относится к медицине, а именно к способам неспецифической иммунопрофилактики вирусных инфекций. Изобретение позволяет обеспечить повышение профилактического эффекта при возможных аэрогенных инфекциях, вызываемых вирусами венесуэльского энцефаломиелита лошадей, Марбург и Эбола. В способе профилактики аэрогенных инфекций, вызываемых вирусами венесуэльского энцефаломиелита лошадей, Марбург и Эбола, включающем парентеральное введение в организм препаратов, содержащих индуктор интерферона и/или иммуномодулятор до начала или в период возможного попадания возбудителя заболевания в организм аэрогенным путем, согласно изобретению, одновременно с парентеральным введением препаратов в организм эти препараты дополнительно и в тех же дозах вводят интраназально, причем в качестве профилактических препаратов используют реаферон или ридостин, или реаферон с ридостином, или реаферон с полирибонатом, или реаферон с ридостином и полирибонатом, которые вводят в организм не чаще 2 раз в сут в суммарных дозах: реаферон 1,0-100,0•106 МЕ/кг; ридостин 1,0-8,0 мг/кг; полирибонат 10,0-100,0 мг/кг.The invention relates to medicine, namely to methods for non-specific immunoprophylaxis of viral infections. The invention allows to increase the prophylactic effect in case of possible aerogenic infections caused by the viruses of the Venezuelan encephalomyelitis horses, Marburg and Ebola. In a method for the prevention of aerogenic infections caused by the Venezuelan encephalomyelitis viruses of horses, Marburg and Ebola, comprising parenteral administration to the body of preparations containing an interferon inducer and / or immunomodulator prior to or during the possible exposure of the pathogen to the body by the aerogenous route, according to the invention, simultaneously with parenteral the introduction of drugs into the body, these drugs are additionally and intranasally administered at the same doses, and using prophylactic drugs reaferon dissolved or ridostin or reaferon with ridostin or reaferon with poliribonatom or reaferon with ridostin poliribonatom and which is introduced into the body is not more than 2 times per day in the total doses: reaferon 1,0-100,0 • June 10 IU / kg ; ridostin 1.0-8.0 mg / kg; polyribonate 10.0-100.0 mg / kg.
RU95106890/13A 1995-04-28 1995-04-28 Method of prophylaxis of viral aerogenic infections RU2105565C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95106890/13A RU2105565C1 (en) 1995-04-28 1995-04-28 Method of prophylaxis of viral aerogenic infections

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU95106890/13A RU2105565C1 (en) 1995-04-28 1995-04-28 Method of prophylaxis of viral aerogenic infections

Publications (2)

Publication Number Publication Date
RU95106890A true RU95106890A (en) 1997-06-10
RU2105565C1 RU2105565C1 (en) 1998-02-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU95106890/13A RU2105565C1 (en) 1995-04-28 1995-04-28 Method of prophylaxis of viral aerogenic infections

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2585695C1 (en) * 2015-03-12 2016-06-10 Закрытое акционерное общество "Вектор-Медика" (ЗАО "Вектор-Медика") Method of inhibiting infectious activity of ebola virus in experiment

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Publication number Publication date
RU2105565C1 (en) 1998-02-27

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Effective date: 20060429