RU95105847A - METHOD FOR SCREENING EXAMINATION OF WOMEN OF DETROITAL AGE USING TEST SYSTEM ELI-P "FOR FORECASTING THE DEVELOPMENT OF EMBRYO / FETUS AND THE BIRTH OF A HEALTHY OR AN ABNORMAL CHILD" - Google Patents

METHOD FOR SCREENING EXAMINATION OF WOMEN OF DETROITAL AGE USING TEST SYSTEM ELI-P "FOR FORECASTING THE DEVELOPMENT OF EMBRYO / FETUS AND THE BIRTH OF A HEALTHY OR AN ABNORMAL CHILD"

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Publication number
RU95105847A
RU95105847A RU95105847/14A RU95105847A RU95105847A RU 95105847 A RU95105847 A RU 95105847A RU 95105847/14 A RU95105847/14 A RU 95105847/14A RU 95105847 A RU95105847 A RU 95105847A RU 95105847 A RU95105847 A RU 95105847A
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RU
Russia
Prior art keywords
development
eli
fetus
protein
test system
Prior art date
Application number
RU95105847/14A
Other languages
Russian (ru)
Other versions
RU2107913C1 (en
Inventor
А.Б. Полетаев
Н.К. Вабишевич
С.Г. Морозов
Original Assignee
А.Б. Полетаев
Н.К. Вабишевич
С.Г. Морозов
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by А.Б. Полетаев, Н.К. Вабишевич, С.Г. Морозов filed Critical А.Б. Полетаев
Priority to RU95105847A priority Critical patent/RU2107913C1/en
Priority claimed from RU95105847A external-priority patent/RU2107913C1/en
Publication of RU95105847A publication Critical patent/RU95105847A/en
Application granted granted Critical
Publication of RU2107913C1 publication Critical patent/RU2107913C1/en

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Claims (1)

Способ скрининга женщин детородного возраста с ранними сроками беременности или до беременности, включающий забор крови, получение сыворотки, получение тест-системы ELI-P (очищенные тест-антигены) и проведение твердофазного иммуноферментного анализа, отличающийся тем, что определяют иммунореактивность сывороточных аутоантител организма женщины, оказывающих существенное влияние на нормальный эмбрио/фетогенез и направленных к антигенам, непосредственно участвующим в процессах развития органов и тканей плода, например к основному белку миелина, белку S100, анионному прочносвязанному белку хроматина АБХ 14-18, мембранному белку МР65, и при получении данных об отклонении иммунореактивности тестируемых сывороток от уровня нормальных значений к любому из них по степени выраженности отклонений определяют уровень риска нарушений развития плода, исходя из данных "Таблицы прогноза", составленной на основе анализа накопленных банков данных.A method for screening women of childbearing age with early pregnancy or before pregnancy, including blood sampling, obtaining serum, obtaining the ELI-P test system (purified test antigens) and conducting an enzyme-linked immunosorbent assay, characterized in that the immunoreactivity of the serum autoantibodies of a woman’s body is determined, having a significant effect on normal embryo / fetogenesis and directed to antigens directly involved in the development of organs and tissues of the fetus, for example, to the main protein myelin, S100 protein, ABH 14-18 anion tightly bound chromatin protein, MP65 membrane protein, and when receiving data on the deviation of the immunoreactivity of the tested sera from the level of normal values to any of them, the risk level of fetal development disorders is determined by the degree of severity of the deviations, based on the data " Forecast Tables ”, compiled on the basis of the analysis of accumulated data banks.
RU95105847A 1995-04-14 1995-04-14 Method for performing screening examination of women of productive age by means of eli-p test system to predict embryo/fetus development and birth of healthy or anomalous baby RU2107913C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95105847A RU2107913C1 (en) 1995-04-14 1995-04-14 Method for performing screening examination of women of productive age by means of eli-p test system to predict embryo/fetus development and birth of healthy or anomalous baby

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE09400706 1994-07-26
RU95105847A RU2107913C1 (en) 1995-04-14 1995-04-14 Method for performing screening examination of women of productive age by means of eli-p test system to predict embryo/fetus development and birth of healthy or anomalous baby
BE09500448 1995-05-17

Publications (2)

Publication Number Publication Date
RU95105847A true RU95105847A (en) 1997-09-27
RU2107913C1 RU2107913C1 (en) 1998-03-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU95105847A RU2107913C1 (en) 1995-04-14 1995-04-14 Method for performing screening examination of women of productive age by means of eli-p test system to predict embryo/fetus development and birth of healthy or anomalous baby

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RU (1) RU2107913C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4820003B2 (en) * 1998-11-05 2011-11-24 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン S100 protein and autoantibodies as serum markers for cancer

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